Imperial College London
Alternate

ProfessorNaomiChayen

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Prof Res Fellow - Professor of Biomedical Sciences
 
 
 
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Contact

 

+44 (0)20 7594 3240n.chayen Website

 
 
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Location

 

Office no. E304Burlington DanesHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Levenstein:2019:10.1002/adfm.201808172,
author = {Levenstein, MA and Anduix-Canto, C and Kim, YY and Holden, MA and González, Niño C and Green, DC and Foster, SE and Kulak, AN and Govada, L and Chayen, NE and Day, SJ and Tang, CC and Weinhausen, B and Burghammer, M and Kapur, N and Meldrum, FC},
doi = {10.1002/adfm.201808172},
journal = {Advanced Functional Materials},
title = {Droplet microfluidics XRD identifies effective nucleating agents for calcium carbonate},
url = {http://dx.doi.org/10.1002/adfm.201808172},
volume = {29},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The ability to control crystallization reactions is required in a vast range of processes including the production of functional inorganic materials and pharmaceuticals and the prevention of scale. However, it is currently limited by a lack of understanding of the mechanisms underlying crystal nucleation and growth. To address this challenge, it is necessary to carry out crystallization reactions in well-defined environments, and ideally to perform in situ measurements. Here, a versatile microfluidic synchrotron-based technique is presented to meet these demands. Droplet microfluidic-coupled X-ray diffraction (DMC-XRD) enables the collection of time-resolved, serial diffraction patterns from a stream of flowing droplets containing growing crystals. The droplets offer reproducible reaction environments, and radiation damage is effectively eliminated by the short residence time of each droplet in the beam. DMC-XRD is then used to identify effective particulate nucleating agents for calcium carbonate and to study their influence on the crystallization pathway. Bioactive glasses and a model material for mineral dust are shown to significantly lower the induction time, highlighting the importance of both surface chemistry and topography on the nucleating efficiency of a surface. This technology is also extremely versatile, and could be used to study dynamic reactions with a wide range of synchrotron-based techniques.
AU  - Levenstein,MA
AU  - Anduix-Canto,C
AU  - Kim,YY
AU  - Holden,MA
AU  - González,Niño C
AU  - Green,DC
AU  - Foster,SE
AU  - Kulak,AN
AU  - Govada,L
AU  - Chayen,NE
AU  - Day,SJ
AU  - Tang,CC
AU  - Weinhausen,B
AU  - Burghammer,M
AU  - Kapur,N
AU  - Meldrum,FC
DO  - 10.1002/adfm.201808172
PY  - 2019///
SN  - 1616-301X
TI  - Droplet microfluidics XRD identifies effective nucleating agents for calcium carbonate
T2  - Advanced Functional Materials
UR  - http://dx.doi.org/10.1002/adfm.201808172
UR  - http://hdl.handle.net/10044/1/68650
VL  - 29
ER  -
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