I am a Sir Henry Dale fellow in the Bacterial Evolutionary Epidemiology group at the MRC Centre for Global Infectious Disease Analysis, near Paddington. My work focusses on the biology of multi-strain bacterial populations, primarily Streptococcus pneumoniae (the pneumococcus). Such microbes often vary extensively in characteristics such as antibiotic resistance, virulence and expression of antigens that are potential vaccine targets. To understand this variation, my research encompasses laboratory molecular microbiology, analysis of genomic datasets, and computational modelling. Repeated emails are the best way to contact me.
Lochen A, Croucher N, Anderson R, 2020, Divergent serotype replacement trends and increasing diversity in pneumococcal disease in high income settings reduce the benefit of expanding vaccine valency, Scientific Reports, ISSN:2045-2322
et al., 2020, Frequency-dependent selection can forecast evolution in Streptococcus pneumoniae., Plos Biol, Vol:18
et al., 2020, Lineage-specific evolution and gene flow inListeria monocytogenesare independent of bacteriophages, Environmental Microbiology, ISSN:1462-2912
et al., 2020, Negative frequency-dependent selection and asymmetrical transformation stabilise multi-strain bacterial population structures
et al., 2020, Visualizing variation within Global Pneumococcal Sequence Clusters (GPSCs) and country population snapshots to contextualize pneumococcal isolates, Microbial Genomics, Vol:6, ISSN:2057-5858