Imperial College London

DrNicholasCroucher

Faculty of MedicineSchool of Public Health

Senior Lecturer in Bacterial Genomics
 
 
 
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Contact

 

+44 (0)20 7594 3820n.croucher

 
 
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Location

 

UG5Norfolk PlaceSt Mary's Campus

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Summary

 

Summary

I am a Sir Henry Dale fellow in the Bacterial Evolutionary Epidemiology group at the MRC Centre for Global Infectious Disease Analysis, near Paddington. My work focusses on the biology of multi-strain bacterial populations, primarily Streptococcus pneumoniae (the pneumococcus). Such microbes often vary extensively in characteristics such as antibiotic resistance, virulence and expression of antigens that are potential vaccine targets. To understand this variation, my research encompasses laboratory molecular microbiology, analysis of genomic datasets, and computational modelling. Repeated emails are the best way to contact me.

Publications

Journals

Dewe TCM, D'Aetht JC, Croucher NJ, 2019, Genomic epidemiology of penicillin-non-susceptible Streptococcus pneumoniae, Microbial Genomics, Vol:5, ISSN:2057-5858

Kwun M, Oggioni MR, Bentley SD, et al., 2019, Synergistic activity of mobile genetic element defences in Streptococcus pneumoniae, Genes, Vol:10, ISSN:2073-4425

De Ste Croix M, Chen Y, Vacca I, et al., 2019, Recombination of the phase variable spnIII locus is independent of all known pneumococcal site-specific recombinases, Journal of Bacteriology, Vol:201, ISSN:0021-9193

Lehtinen S, Chewapreecha C, Lees J, et al., 2019, Horizontal gene transfer rate is not the primary determinant of observed antibiotic resistance frequencies in Streptococcus pneumoniae

Lees JA, Ferwerda B, Kremer PHC, et al., 2019, Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis, Nature Communications, Vol:10, ISSN:2041-1723

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