Imperial College London

DrNicholasCroucher

Faculty of MedicineSchool of Public Health

Reader in Bacterial Genomics
 
 
 
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Contact

 

+44 (0)20 7594 3820n.croucher

 
 
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Location

 

1104Building E - Sir Michael UrenWhite City Campus

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Summary

 

Summary

I am a Sir Henry Dale fellow in the Bacterial Evolutionary Epidemiology group at the MRC Centre for Global Infectious Disease Analysis, near Paddington. My work focusses on the biology of multi-strain bacterial populations, primarily Streptococcus pneumoniae (the pneumococcus). Such microbes often vary extensively in characteristics such as antibiotic resistance, virulence and expression of antigens that are potential vaccine targets. To understand this variation, my research encompasses laboratory molecular microbiology, analysis of genomic datasets, and computational modelling. Repeated emails are the best way to contact me.

Publications

Journals

Croucher N, Kwun MJ, Alexandru I, et al., 2022, Post-vaccine epidemiology of serotype 3 pneumococci identifies transformation inhibition through prophage-driven alteration of a non-coding RNA, Genome Medicine: Medicine in the Post-genomic Era, ISSN:1756-994X

Tonkin-Hill G, Ling C, Chaguza C, et al., 2022, Pneumococcal within-host diversity during colonization, transmission and treatment, Nature Microbiology, Vol:7, ISSN:2058-5276, Pages:1791-+

Mallawaarachchi S, Tonkin-Hill G, Croucher NJ, et al., 2022, Genome-wide association, prediction and heritability in bacteria with application to Streptococcus pneumoniae, Nar Genomics and Bioinformatics, Vol:4, ISSN:2631-9268, Pages:1-11

Chaguza C, Tonkin-Hill G, Lo SW, et al., 2022, RCandy: an R package for visualizing homologous recombinations in bacterial genomes, Bioinformatics, Vol:38, ISSN:1367-4803, Pages:1450-1451

Lochen A, Truscott JE, Croucher NJ, 2022, Analysing pneumococcal invasiveness using Bayesian models of pathogen progression rates, Plos Computational Biology, Vol:18, ISSN:1553-734X

More Publications