I am a Sir Henry Dale fellow in the Bacterial Evolutionary Epidemiology group at the MRC Centre for Global Infectious Disease Analysis, near Paddington. My work focusses on the biology of multi-strain bacterial populations, primarily Streptococcus pneumoniae (the pneumococcus). Such microbes often vary extensively in characteristics such as antibiotic resistance, virulence and expression of antigens that are potential vaccine targets. To understand this variation, my research encompasses laboratory molecular microbiology, analysis of genomic datasets, and computational modelling. Repeated emails are the best way to contact me.
Croucher N, Joshua D, 2021, The role of interspecies recombinations in the evolution of antibiotic-resistant pneumococci, Elife, ISSN:2050-084X
et al., 2021, Emergence and dissemination of antimicrobial resistance in Escherichia coli causing bloodstream infections in Norway in 2002-17: a nationwide, longitudinal, microbial population genomic study, The Lancet Microbe, Vol:2, ISSN:2666-5247, Pages:E331-E341
et al., 2021, Negative frequency-dependent selection and asymmetrical transformation stabilise multi-strain bacterial population structures, The Isme Journal: Multidisciplinary Journal of Microbial Ecology, Vol:15, ISSN:1751-7362, Pages:1523-1538
Lochen A, Croucher N, Anderson R, 2020, Divergent serotype replacement trends and increasing diversity in pneumococcal disease in high income settings reduce the benefit of expanding vaccine valency, Scientific Reports, Vol:10, ISSN:2045-2322
et al., 2020, Frequency-dependent selection can forecast evolution in Streptococcus pneumoniae, Plos Biology, Vol:18, ISSN:1544-9173