Publications
142 results found
Tassone D, Ding N, 2020, A review of adverse events associated with immunosuppressive treatments in inflammatory bowel disease patients, Publisher: OXFORD UNIV PRESS, Pages: S453-S453, ISSN: 1873-9946
Adegbola S, Sarafian M, Sahnan K, et al., 2020, Metabonomic profiling distinguishes Crohn's perianal fistulas and idiopathic idiopathic (cryptoglandular) perianal fistulas: possible clues to underlying pathogenesis?, Publisher: OXFORD UNIV PRESS, Pages: S174-S174, ISSN: 1873-9946
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- Citations: 2
Lee T, Gilbert L, Srinivasan A, et al., 2020, Higher anti-TNF α trough levels are not associated with increased radiological response in perianal fistulising Crohn's disease: A multicentre study, Publisher: OXFORD UNIV PRESS, Pages: S449-S449, ISSN: 1873-9946
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- Citations: 1
Ferguson A, Ding N, Connell W, et al., 2020, Validation of the 'IBD Disk' in clinical practice, Publisher: OXFORD UNIV PRESS, Pages: S472-S472, ISSN: 1873-9946
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- Citations: 1
Bokemeyer A, Tepasse PR, Quill L, et al., 2019, Quantitative Phase Imaging Using Digital Holographic Microscopy Reliably Assesses Morphology and Reflects Elastic Properties of Fibrotic Intestinal Tissue, SCIENTIFIC REPORTS, Vol: 9, ISSN: 2045-2322
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- Citations: 15
Bettenworth D, Muecke MM, Lopez R, et al., 2019, Efficacy of Endoscopic Dilation of Gastroduodenal Crohn's Disease Strictures: A Systematic Review and Meta-Analysis of Individual Patient Data, CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, Vol: 17, Pages: 2514-+, ISSN: 1542-3565
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- Citations: 23
Wann S, Macisaac M, Powles T, et al., 2019, Male patients, older patients, inpatients, and patients living further away are more likely to have poor bowel preparation for colonoscopy, which results in reduced polyp detection rates, Publisher: WILEY, Pages: 224-225, ISSN: 0815-9319
Wann S, Norris R, Williams R, et al., 2019, Endoscopic and histological disease activity in ulcerative colitis is associated with nonresponse to biological therapy, Publisher: WILEY, Pages: 133-133, ISSN: 0815-9319
Ferguson A, Taylor A, Robinson C, et al., 2019, Assessing the adequacy of bowel preparation information: The patient's perspective, Publisher: WILEY, Pages: 210-210, ISSN: 0815-9319
Ferguson A, Williams J, Flanagan E, et al., 2019, Validation of the Inflammatory Bowel Disease Disk in clinical practice, Publisher: WILEY, Pages: 162-162, ISSN: 0815-9319
Torres J, Ellul P, Langhorst J, et al., 2019, European Crohn's and Colitis Organisation Topical Review on Complementary Medicine and Psychotherapy in Inflammatory Bowel Disease, JOURNAL OF CROHNS & COLITIS, Vol: 13, Pages: 673-+, ISSN: 1873-9946
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- Citations: 67
Lee T, Ding N, 2019, MRI outcomes in perianal fistulising Crohn's disease following anti-TNF-α therapy: a systematic review and meta-analysis, Publisher: OXFORD UNIV PRESS, Pages: S278-S279, ISSN: 1873-9946
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- Citations: 1
Choi C-HR, Al Bakir I, Ding N-SJ, et al., 2019, Cumulative burden of inflammation predicts colorectal neoplasia risk in ulcerative colitis: a large single-centre study, GUT, Vol: 68, Pages: 414-422, ISSN: 0017-5749
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- Citations: 94
Lee T, Kamm M, Bell S, et al., 2019, Radiological outcomes in perianal fistulising Crohn's disease, Publisher: OXFORD UNIV PRESS, Pages: S368-S369, ISSN: 1873-9946
Boyapati R, Fehily SR, Ding NS, 2019, European clinician perspective on withdrawing immunosuppression, Publisher: OXFORD UNIV PRESS, Pages: S324-S324, ISSN: 1873-9946
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- Citations: 1
Wright EK, Ding NS, Niewiadomski O, 2018, Management of inflammatory bowel disease, MEDICAL JOURNAL OF AUSTRALIA, Vol: 209, Pages: 318-323, ISSN: 0025-729X
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- Citations: 37
Segal J, Penez L, Mohsen S, et al., 2018, Long term outcomes of initial Infliximab therapy for inflammatory pouch pathology: a multi-centre retrospective study, Scandinavian Journal of Gastroenterology, Vol: 53, Pages: 1051--1058, ISSN: 0036-5521
Background: Restorative proctocolectomy with ileal pouch-anal anastomosis is considered the procedure of choice in patients with ulcerative colitis refractory to medical therapy. Subsequent inflammation of the pouch is a common complication and in some cases pouchitis fails to respond to antibiotics, the mainstay of treatment. In such cases, corticosteroids, immunomodulatory or biologic treatments are options. However, our understanding of the efficacy of anti-tumour necrosis factor medications in both chronic pouchitis and Crohn’s-like inflammation are based on studies that include relatively small numbers of patients. Methods: This was an observational, retrospective, multi-centre study to assess the long-term effectiveness and safety of infliximab for inflammatory disorders related to the ileoanal pouch. The primary outcome was the development of infliximab failure defined by early failure to infliximab or secondary loss of response to infliximab. Results: Thirty-four patients met the inclusion criteria; 18/34 (53%) who were initiated on infliximab for inflammatory disorders of the pouch had infliximab failure, 3/34 (8%) had early failure, and 15/34 (44%) had secondary loss of response with a median follow-up of 280 days (range 3-47 months). In total, 24/34 (71%) avoided an ileostomy by switching to other medical therapies at a median follow-up of follow-up of 366 days (1-130 months). Conclusions:Initial infliximab therapy for pouch inflammatory conditions is associated with Infliximab failure in just over half of all patients. Despite a high failure rate, an ileostomy can be avoided in almost three quarters of patients at four years by using other medical therapies.
Lee T, Ding N, 2018, Radiological outcomes in perianal fistulizing Crohn's disease treated with anti-TNFα therapy: A systematic review and meta-analysis, Publisher: WILEY, Pages: 99-100, ISSN: 0815-9319
Lee T, Kamm M, Bell S, et al., 2018, Predictors of long-term radiological outcomes in perianal fistulizing Crohn's disease, Publisher: WILEY, Pages: 99-99, ISSN: 0815-9319
Wu K, Connell W, Bell S, et al., 2018, Clinical outcomes and management of patients with concomitant primary sclerosing cholangitis and inflammatory bowel disease, Publisher: WILEY, Pages: 114-114, ISSN: 0815-9319
Worland T, Cronin O, Harrison B, et al., 2018, Clinical and financial impacts of introducing a dedicated endoscopic mucosal resection service for treating patients with large colonic polyps in a regional tertiary hospital: A 9-year prospective study, Publisher: WILEY, Pages: 13-14, ISSN: 0815-9319
Garg M, Hendy P, Ding JN, et al., 2018, The Effect of Vitamin D on Intestinal Inflammation and Faecal Microbiota in Patients with Ulcerative Colitis, JOURNAL OF CROHNS & COLITIS, Vol: 12, Pages: 963-972, ISSN: 1873-9946
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- Citations: 67
Segal J, Penez L, Elkady S, et al., 2018, IDDF2018-ABS-0056 Long term outcomes of initial infliximab therapy for inflammatory pouch pathology: a multi-centre retrospective study, International Digestive Disease Forum 2018, Publisher: BMJ Publishing Group, Pages: A41-A41, ISSN: 0017-5749
Segal J, Penez L, Elkady SM, et al., 2018, PWE-052 Long term outcomes of initial IFX therapy for inflammatory pouch pathology: a multi-centre retrospective study, British Society of Gastroenterology, Annual General Meeting, Publisher: BMJ Publishing Group, Pages: A93-A93, ISSN: 0017-5749
Ricciuto A, Al-Darmaki A, Stewart MJ, et al., 2018, BIOLOGICAL INTERVENTIONS FOR INDUCTION AND MAINTENANCE OF MUCOSAL HEALING IN ULCERATIVE COLITIS: A COCHRANE SYSTEMATIC REVIEW, Annual Meeting of the American-Society-for-Gastrointestinal-Endoscopy / Digestive Disease Week, Publisher: W B SAUNDERS CO-ELSEVIER INC, Pages: S382-S382, ISSN: 0016-5085
Burisch J, Gisbert JP, Siegmund B, et al., 2018, Validation of the 'United Registries for Clinical Assessment and Research' [UR-CARE], a European Online Registry for Clinical Care and Research in Inflammatory Bowel Disease, JOURNAL OF CROHNS & COLITIS, Vol: 12, Pages: 532-537, ISSN: 1873-9946
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- Citations: 5
Bettenworth D, Mucke MM, Singh A, et al., 2018, EFFICACY, SAFETY AND LONG-TERM OUTCOME OF ENDOSCOPIC DILATION THERAPY FOR CROHN'S DISEASE STRICTURES OF THE UPPER GASTROINTESTINAL TRACT - AN INTERNATIONAL MULTICENTER COHORT STUDY INCLUDING 99 PATIENTS AND 129 DILATION PROCEDURES, Annual Meeting of the American-Society-for-Gastrointestinal-Endoscopy / Digestive Disease Week, Publisher: W B SAUNDERS CO-ELSEVIER INC, Pages: S1033-S1034, ISSN: 0016-5085
Bettenworth D, Bokemeyer A, Poremba C, et al., 2018, Quantitative phase microscopy for evaluation of intestinal inflammation and wound healing utilizing label-free biophysical markers, HISTOLOGY AND HISTOPATHOLOGY, Vol: 33, Pages: 417-432, ISSN: 0213-3911
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- Citations: 22
Segal JP, Ding NS, Worley G, 2018, Systematic review with meta-analysis: the management of chronic refractory pouchitis with an evidence-based treatment algorithm (vol 45, pg 581, 2017), ALIMENTARY PHARMACOLOGY & THERAPEUTICS, Vol: 47, Pages: 864-864, ISSN: 0269-2813
Misra R, Sarafian M, Pechilvanis A, et al., 2018, South Asian ethnicity drives differences in microbial and metabolic profiling in a newly diagnosed ulcerative colitis cohort, Publisher: OXFORD UNIV PRESS, Pages: S120-S121, ISSN: 1873-9946
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