Imperial College London

Dr Neil Dufton

Faculty of MedicineNational Heart & Lung Institute

Research Associate
 
 
 
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Contact

 

+44 (0)20 7594 2728n.dufton

 
 
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Location

 

525W5ICTEM buildingHammersmith Campus

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Summary

 

Summary

Career Summary

 

Neil Dufton graduated from the University of Bath with a BSc (Hon) Pharmacology in 2006. He went on to undertake a PhD at the William Harvey Research Institute within the Bart's and the London Medical School with Professors Perretti and Flower. The project focused on the interaction of the anti-inflammatory protein Annexin 1 with its receptor FPR2/ALX  in regulating innate immunology and the resolution of inflammation.

In 2010 he moved to Canada for two years to work with Professor John Wallace at the Farncombe Family Digestive Health Research Institute, McMaster University investigating the role of hydrogen sulfide gas in regulating inflammation. 

Neil became a post-doctoral research associate at the National Heart and Lung Institute (NHLI) at Imperial College London in 2012 with Prof. Anna Randi. Neil's current research interests include vascular inflammation, endothelial homeostasis and angiogenesis.

No Smoke without Fire

An unstable 'leaky' blood vessel

 

Illustration and Public engagement

In 2011 Neil designed a website, www.notproperlydone.com, to showcase his artistic and scientific capabilities to a wider audience. He has had illustrations published in seven publications and have also designed logos for two conferences (7th International Conference on Annexins and Focus on Translational Immunology). Two of his illustrations have been accepted into the Wellcome Image Collection and he had his first his first exhbition entitled Auto-Biology‎ in October 2014.

Flow Cytometry

a neutrophil passing through the laser in a flow cytometer

 

At the NHLI he is actively involved with public engagement as scientific consultant on an interactive exhibit Blood Lines and the Heart and Lung Repair Shop (click on the link to see his shop demo about blood vessel growth). Outside of Imperial Neil has worked with animators Genetic Moo to develop at interactive blister model as part of Silent Signals a Wellcome Trust funded project produced by Animate.

 

Publications

Journals

Dufton NP, peghaire CR, Osuna-Almagro L, et al., Dynamic regulation of canonical TGFβ signaling by endothelial transcription factor ERG protects from liver fibrogenesis, Nature Communications, ISSN:2041-1723

Perbellini F, Watson SA, Scigliano M, et al., 2017, Investigation of cardiac fibroblasts using myocardial slices, Cardiovascular Research, ISSN:1755-3245

Shah AV, Birdsey GM, Peghaire C, et al., 2017, The endothelial transcription factor ERG mediates Angiopoietin-1-dependent control of Notch signalling and vascular stability, Nature Communications, Vol:8, ISSN:2041-1723

Beuerle MG, Dufton NP, Randi AM, et al., 2016, Molecular dynamics studies on the DNA-binding process of ERG, Molecular Biosystems, Vol:12, ISSN:1742-206X, Pages:3600-3610

Birdsey GM, Shah AV, Dufton N, et al., 2015, The Endothelial Transcription Factor ERG Promotes Vascular Stability and Growth through Wnt/beta-Catenin Signaling, Developmental Cell, Vol:32, ISSN:1534-5807, Pages:82-96

More Publications