Imperial College London

Professor Nick Franks, FRS

Faculty of Natural SciencesDepartment of Life Sciences

Professor of Biophysics and Anaesthetics



+44 (0)20 7594 7629n.franks Website




401ASir Ernst Chain BuildingSouth Kensington Campus





My central research interest is in understanding how general anaesthetics act. I have worked on this problem mainly at the molecular and cellular levels but more recently I have become interested in how anaesthetics act at the level of neuronal networks and have been pursuing the possibility that the sedative and hypnotic actions of general anaesthetics may be mediated through the same neuronal pathways that control natural sleep. I work closely with Bill Wisden and Stephen Brickley.

My publications from Google Scholar

My profile from ORCID

Current Group members

Nick and BillWei and RaquelKyoko and GiuliaYing and LedaBerta and DavidEd and ChrisEd and XiaoBryan and Mathieu



Lily, Alessandro and Chris

Rowan,Valentina,FabiaCigdem, Ed and Rowan



Koziakova M, Harris K, Edge C, et al., 2019, Noble gas neuroprotection: Xenon and argon protect against hypoxic-ischaemic injury in rat hippocampus in vitro via distinct mechanisms, British Journal of Anaesthesia, ISSN:1471-6771, Pages:601-609

Yu X, Ma Y, Harding EC, et al., 2019, Corrigendum: Genetic lesioning of histamine neurons increases sleep-wake fragmentation and reveals their contribution to modafinil-induced wakefulness., Sleep, Vol:42

Ma Y, Miracca G, Yu X, et al., Galanin neurons unite sleep homeostasis and alpha2 adrenergic sedation, Current Biology, ISSN:1879-0445


Campos-Pires R, Mohamed-Ali N, Balaet M, et al., 2019, Xenon prevents early neuronal loss and neuroinflammation in a rat model of traumatic brain injury, BJA Research Forum / Anaesthetic Research Society, Elsevier, Pages:e508-e509, ISSN:0007-0912

Hsieh B, Harding E, Wisden W, et al., A Miniature Neural Recording Device to Investigate Sleep and Temperature Regulation in Mice, IEEE Biomedical Circuits and Systems (BioCAS) Conference

More Publications