Summary
My central research interest is in understanding how general anaesthetics act. I have worked on this problem mainly at the molecular and cellular levels but more recently I have become interested in how anaesthetics act at the level of neuronal networks and have been pursuing the possibility that the sedative and hypnotic actions of general anaesthetics may be mediated through the same neuronal pathways that control natural sleep.
My laboratory is merged with that of Bill Wisden and our joint website can be found here: franks-wisden-lab.
My publications from Google Scholar
Current Group members
PREVIOUS GROUP MEMBERS
Publications
Journals
Franks NP, Wisden W, 2021, The inescapable drive to sleep: Overlapping mechanisms of sleep and sedation, Science, Vol:374, ISSN:0036-8075, Pages:556-559
Harding EC, Ba W, Zahir R, et al., 2021, Nitric oxide synthase neurons in the preoptic hypothalamus are NREM and REM sleep-active and lower body temperature, Frontiers in Neuroscience, Vol:15, ISSN:1662-453X
Yu X, Ba W, Zhao G, et al., 2021, Dysfunction of ventral tegmental area GABA neurons causes mania-like behavior, Molecular Psychiatry, Vol:26, ISSN:1359-4184, Pages:5213-5228
Conference
Pires RC, Macdonald W, Edge CJ, et al., 2021, Xenon prevents neuroinflammation in a novel model of blast traumatic brain injury in rats, LIPPINCOTT WILLIAMS & WILKINS, Pages:947-947, ISSN:0003-2999
Pires RC, Mohamed-Ali N, Aldhoun J, et al., 2021, Moderate hypothermia combined with xenon, but not hypothermia alone, reduces secondary injury development after traumatic brain injury in rats, LIPPINCOTT WILLIAMS & WILKINS, Pages:946-946, ISSN:0003-2999