Imperial College London

Professor Nick Franks, FRS

Faculty of Natural SciencesDepartment of Life Sciences

Professor of Biophysics and Anaesthetics
 
 
 
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Contact

 

+44 (0)20 7594 7624n.franks Website

 
 
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Location

 

401ASir Ernst Chain BuildingSouth Kensington Campus

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Summary

 

Summary

My central research interest is in understanding how general anaesthetics act. I have worked on this problem mainly at the molecular and cellular levels but more recently I have become interested in how anaesthetics act at the level of neuronal networks and have been pursuing the possibility that the sedative and hypnotic actions of general anaesthetics may be mediated through the same neuronal pathways that control natural sleep. 

My laboratory is merged with that of Bill Wisden and our joint website can be found here: franks-wisden-lab.

My publications from Google Scholar

My profile from ORCID

Current Group members

Nick and BillWei and RaquelKyoko and GiuliaYing and LedaBerta and DavidEd and ChrisEd and XiaoBryan and Mathieu

PREVIOUS GROUP MEMBERS

 

Lily, Alessandro and Chris

Rowan,Valentina,FabiaCigdem, Ed and Rowan
Qianzi,Zhiwen,XiaoEd,Elly,DaveRaquel,Anna,Zhe

Publications

Journals

Wisden W, Franks NP, 2023, Biochemical pathways of sleep., Cell Res

Yu X, Zhao G, Wang D, et al., 2022, A specific circuit in the midbrain detects stress and induces restorative sleep, Science, Vol:377, ISSN:1095-9203, Pages:1-10

Miracca G, Anuncibay Soto B, Tossell K, et al., 2022, NMDA receptors in the lateral preoptic hypothalamus are essential for sustaining NREM and REM sleep, The Journal of Neuroscience, Vol:42, ISSN:0270-6474, Pages:5389-5409

Franks NP, Wisden W, 2021, The inescapable drive to sleep: Overlapping mechanisms of sleep and sedation, Science, Vol:374, ISSN:0036-8075, Pages:556-559

Conference

Tossell K, Yu X, Soto BA, et al., 2022, NEURONS IN PREFRONTAL CORTEX RESPOND TO SLEEP DEPRIVATION BY INITIATING SLEEP PREPARATORY BEHAVIOUR AND NREM SLEEP, ELSEVIER, Pages:S20-S20, ISSN:1389-9457

More Publications