My central research interest is in understanding how general anaesthetics act. I have worked on this problem mainly at the molecular and cellular levels but more recently I have become interested in how anaesthetics act at the level of neuronal networks and have been pursuing the possibility that the sedative and hypnotic actions of general anaesthetics may be mediated through the same neuronal pathways that control natural sleep.
My laboratory is merged with that of Bill Wisden and our joint website can be found here: franks-wisden-lab.
Current Group members
PREVIOUS GROUP MEMBERS
Harding EC, Franks NP, Wisden W, 2020, Sleep and thermoregulation, Current Opinion in Physiology, Vol:15, ISSN:2468-8673, Pages:7-13
et al., Dysfunction of ventral tegmental area GABA neurons causes mania-like behavior., Molecular Psychiatry, ISSN:1359-4184
Nollet M, Wisden W, Franks N, 2020, Sleep deprivation and stress - a reciprocal relationship, Interface Focus, Vol:10, ISSN:2042-8901, Pages:1-11
Wisden W, Franks NP, 2020, The stillness of sleep., Scienc, Vol:367, ISSN:1095-9203, Pages:366-367
et al., 2019, Noble gas neuroprotection: Xenon and argon protect against hypoxic-ischaemic injury in rat hippocampus in vitro via distinct mechanisms, British Journal of Anaesthesia, Vol:123, ISSN:1471-6771, Pages:601-609