Imperial College London
Alternate

Professor Nick Franks, FRS

Faculty of Natural Sciences, Department of Life Sciences

Professor of Biophysics and Anaesthetics
 
 
 
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Contact

 

+44 (0)20 7594 7624n.franks Website

 
 
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Location

 

401ASir Ernst Chain BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@inproceedings{Hsieh:2019:10.1109/BIOCAS.2019.8918722,
author = {Hsieh, B and Harding, E and Wisden, W and Franks, N and Constandinou, T},
doi = {10.1109/BIOCAS.2019.8918722},
pages = {1--4},
publisher = {IEEE},
title = {A miniature neural recording device to investigate sleep and temperature regulation in mice},
url = {http://dx.doi.org/10.1109/BIOCAS.2019.8918722},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - CPAPER
AB  - Sleep  is  an  important  and  ubiquitous  process  that,despite   decades   of   research,   a   large   part   of   its   underlyingbiological  circuity  still  remain  elusive.  To  conduct  research  inthis   field,   many   devices   capable   of   recording   neural   signalssuch  as  LFP  and  EEG  have  been  developed.  However,  most  ofthese  devices  are  unsuitable  for  sleep  studies  in  mice,  the  mostcommonly used animals, due to their size and weight. Thus, thispaper  presents  a  novel  4  channel,  compact  (  2.1cm  by  1.7cm  )and  lightweight  (  3.6g  )  neural-logging  device  that  can  recordfor  3  days  on  just  two  0.6g  zinc  air  312  batteries.  Instead  ofthe  typical  solution  of  using  multiple  platforms,  the  presenteddevice  integrates  high  resolution  EEG,  EMG  and  temperaturerecordings  into  one  platform.  The  onboard  BLE  module  allowsthe device to be controlled wirelessly as well as stream data in realtime, enabling researchers to check the progress of the recordingwith  minimal  animal  disturbance.  The  device  demonstrates  itsability to accurately record EEG and temperature data throughthe  long  24  hour  in-vivo  recordings  conducted.  The  obtainedEEG  data  could  be  easily  sleep  scored  and  the  temperaturesvalues  were  all  within  expected  physiological  range.
AU  - Hsieh,B
AU  - Harding,E
AU  - Wisden,W
AU  - Franks,N
AU  - Constandinou,T
DO  - 10.1109/BIOCAS.2019.8918722
EP  - 4
PB  - IEEE
PY  - 2019///
SP  - 1
TI  - A miniature neural recording device to investigate sleep and temperature regulation in mice
UR  - http://dx.doi.org/10.1109/BIOCAS.2019.8918722
UR  - https://ieeexplore.ieee.org/document/8918722
UR  - http://hdl.handle.net/10044/1/74992
ER  -
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