Publications

BibTex format

@article{Parker:2019:infdis/jiy553,
author = {Parker, EPK and Whitfield, H and Baskar, C and Giri, S and John, J and Grassly, N and Kang, G and Praharaj, I},
doi = {infdis/jiy553},
journal = {Journal of Infectious Diseases},
pages = {578--581},
title = {FUT2 secretor status is not associated with oral poliovirus vaccine immunogenicity in south Indian infants},
url = {http://dx.doi.org/10.1093/infdis/jiy553},
volume = {219},
year = {2019}
}

Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - FUT2 determines whether histo-blood group antigens are secreted at mucosal surfaces. Secretor status influences susceptibility to enteric viruses, potentially including oral poliovirus vaccine (OPV). We performed a nested case–control study to determine the association between FUT2 genotype (single-nucleotide polymorphisms G428A, C302T, and A385T) and seroconversion among Indian infants who received a single dose of monovalent type 3 OPV. Secretor prevalence was 75% (89 of 118) in infants who seroconverted and 80% (97 of 122) in infants who did not seroconvert (odds ratio, 0.79; 95% confidence interval, .43–1.45). Our findings suggest that FUT2 genotype is not a key determinant of variation in OPV immunogenicity.
AU  - Parker,EPK
AU  - Whitfield,H
AU  - Baskar,C
AU  - Giri,S
AU  - John,J
AU  - Grassly,N
AU  - Kang,G
AU  - Praharaj,I
DO  - infdis/jiy553
EP  - 581
PY  - 2019///
SN  - 0022-1899
SP  - 578
TI  - FUT2 secretor status is not associated with oral poliovirus vaccine immunogenicity in south Indian infants
T2  - Journal of Infectious Diseases
UR  - http://dx.doi.org/10.1093/infdis/jiy553
UR  - http://hdl.handle.net/10044/1/64642
VL  - 219
ER  -

Download

ProfessorNicholasGrassly

Contact

Location

Summary

Citation

BibTex format

RIS format (EndNote, RefMan)