Imperial College London
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ProfessorNickHopkinson

Faculty of Medicine, National Heart & Lung Institute

Professor of Respiratory Medicine
 
 
 
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Contact

 

n.hopkinson

 
 
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Location

 

Muscle LabSouth BlockRoyal Brompton Campus

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Summary

 

Publications

Publication Type
Year
to

516 results found

Hopkinson NS, Shah PL, Polkey MI, 2011, Endobronchial Valves for Emphysema, NEW ENGLAND JOURNAL OF MEDICINE, Vol: 364, Pages: 381-382, ISSN: 0028-4793

Journal article

Chang E-T, 2011, Endobronchial Valves for Emphysema, NEW ENGLAND JOURNAL OF MEDICINE, Vol: 364, Pages: 382-382, ISSN: 0028-4793

Journal article

Nacul L, Soljak M, Samarasundera E, Hopkinson NS, Lacerda E, Indulkar T, Flowers J, Walford H, Majeed Aet al., 2011, COPD in England: a comparison of expected, model-based prevalence and observed prevalence from general practice data, Vol: 33, Pages: 108-116

Background Primary care data show that 765 000 people in England have a general practice (GP) diagnosis of chronic obstructive pulmonary disease (COPD). We hypothesized that this underestimates actual prevalence, and compared expected prevalence of COPD for English local authority areas with prevalence of diagnosed COPD.Methods Cross-sectional comparison of GP observed and model-based prevalence estimates (using spirometry data without clinical diagnosis) from the Health Survey for England. Local underdiagnosis of COPD was estimated as the ratio of observed to expected cases. We investigated geographical patterns using classical and geographically weighted regression analysis.Results Both observed and expected prevalence of COPD varied widely between areas. There was evidence of a ‘north–south’ divide, with both observed and modelled prevalence higher in the north. The ratio of diagnosed to expected prevalence varied from 0.20 to 0.95, with a mean of 0.52. Underdiagnosis was more pronounced in urban areas, and is particularly severe in London. The inclusion of GP numbers in the analysis yielded a stronger regression relationship, suggesting primary care supply affects diagnosis.Conclusion Both observed and modelled COPD prevalence varies considerably across England. Cost-effective case-finding strategies should be evaluated, especially in areas where the ratio of observed to expected cases is low.

Journal article

Kelly JL, Crowley O, Smith C, Lim M, Lord V, Polkey MI, Hopkinson NSet al., 2011, Determinants Of The COPD Assessment Test (CAT) Score In Clinical Practice, Publisher: AMER THORACIC SOC, ISSN: 1073-449X

Conference paper

Dodd JW, Hogg L, Nolan J, Jefford H, Grant A, Lord V, Falzon C, Garrod R, Lee C, Polkey MI, Jones P, Man WD-C, Hopkinson NSet al., 2011, The COPD Assessment Test (CAT) - Response To Pulmonary Rehabilitation. A Multicentre, Prospective Study, Publisher: AMER THORACIC SOC, ISSN: 1073-449X

Conference paper

Puthucheary Z, Rawal J, Connolly B, Mcphail M, Ratnayake G, Sidhu P, Shrikrishnapalasuriyar D, Hopkins P, Hopkinson NS, Polkey MI, Rennie M, Rowlerson A, Moxham J, Harridge S, Montgomery H, Hart Net al., 2011, Serial Muscle Ultrasound Can Detect Acute Muscle Loss In Multi-Organ Failure, Publisher: AMER THORACIC SOC, ISSN: 1073-449X

Conference paper

Dodd JW, Shrikrishnapalasuriyar D, Hopkinson NS, Jones Pet al., 2011, Physical Activity & Cognitive Function In Stable Non-Hypoxaemic Patients With Chronic Obstructive Pulmonary Disease (COPD), Publisher: AMER THORACIC SOC, ISSN: 1073-449X

Conference paper

Dodd JW, Van den Broek M, Shrikrishna D, Hopkinson NS, Jones PWet al., 2010, COGNITIVE LOSS IN STABLE NON-HYPDXAEMIC PATIENTS WITH MODERATE CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD), Publisher: B M J PUBLISHING GROUP, Pages: A140-A140, ISSN: 0040-6376

Conference paper

Hopkinson NS, Kemp SV, Toma TP, Hansell DM, Geddes DM, Shah PL, Polkey MIet al., 2010, ATELECTASIS FOLLOWING BRONCHOSCOPIC LUNG VOLUME REDUCTION (BLVR) IS ASSOCIATED WITH IMPROVED SURVIVAL IN COPD, British-Thoracic-Society-Winter-Meeting 2010, Publisher: B M J PUBLISHING GROUP, Pages: A137-A137, ISSN: 0040-6376

Conference paper

Natanek SA, Gosker HR, Slot I, Marsh GS, Langen RCJ, Hopkinson NS, Man WD-C, Moxham J, Kemp PR, Schols AMWJ, Polkey MIet al., 2010, MUSCLE FIBRE ATROPHY AND AEROBIC TO ANAEROBIC FIBRE TYPE SHIFT IN THE QUADRICEPS IN COPD, Publisher: B M J PUBLISHING GROUP, Pages: A139-A139, ISSN: 0040-6376

Conference paper

Natanek SA, Langen RCJ, Gosker HR, Marsh GS, Slot I, Hopkinson NS, Man WD-C, Kemp PR, Moxham J, Schols AMWJ, Polkey MIet al., 2010, NF-KAPPA B (NF-κB) AND ACTIVATOR PROTEIN-1 (AP-1) DNA BINDING IN THE QUADRICEPS OF COPD PATIENTS, Publisher: B M J PUBLISHING GROUP, Pages: A138-A139, ISSN: 0040-6376

Conference paper

Dodd JW, Hogg L, Nolan J, Jefford H, Lord VM, Garrod R, Polkey MI, Jones PW, Man WD-C, Hopkinson NSet al., 2010, THE COPD ASSESSMENT TEST SCORE (CAT): A MULTICENTRE, PROSPECTIVE STUDY OF RESPONSE TO PULMONARY REHABILITATION, British-Thoracic-Society-Winter-Meeting 2010, Publisher: BMJ PUBLISHING GROUP, Pages: A36-A36, ISSN: 0040-6376

Conference paper

Darby AC, Barraclough R, Burge PS, Hopkinson NS, Hoyle JL, Lawson RA, Niven RM, Stenton SC, Warburton CJ, Barber CM, Blanc PD, Curran AD, Fishwick Det al., 2010, COPD CAUSATION; AN ASSESSMENT OF AGREEMENT BETWEEN EXPERT CLINICAL RATERS, British-Thoracic-Society-Winter-Meeting 2010, Publisher: B M J PUBLISHING GROUP, Pages: A77-A78, ISSN: 0040-6376

Conference paper

Moore AJ, Soler RS, Cetti EJ, Sathyapala SA, Hopkinson NS, Roughton M, Moxham J, Polkey MIet al., 2010, Sniff nasal inspiratory pressure versus IC/TLC ratio as predictors of mortality in COPD, RESPIRATORY MEDICINE, Vol: 104, Pages: 1319-1325, ISSN: 0954-6111

Journal article

Rohaut B, Porcher R, Siami S, Bailly-Salin J, Hopkinson NS, Guidoux C, Iacobone E, Sonneville R, Polito A, Aboab J, Gaudry S, Morla O, Amouyal G, Azuar J, Vieillard-Baron A, Annane D, Sharshar Tet al., 2010, Brainstem responses can predict death and delirium in sedated patients in intensive care units, 14th Congress of European-Federation-of-Neurological-Societies, Publisher: WILEY-BLACKWELL, Pages: 572-572, ISSN: 1351-5101

Conference paper

Ghanei M, Naderi M, Kosar AM, Harandi AA, Hopkinson NS, Poursaleh Zet al., 2010, Long-term pulmonary complications of chemical warfare agent exposure in Iraqi Kurdish civilians, INHALATION TOXICOLOGY, Vol: 22, Pages: 719-724, ISSN: 0895-8378

Journal article

Freilich S, Usmani OS, Polkey MI, Hopkinson NSet al., 2010, Emphysema due to smoke from a herbal asthma remedy., JRSM Short Rep, Vol: 1

Journal article

Hopkinson NS, Polkey MI, 2010, Does physical inactivity cause chronic obstructive pulmonary disease?, CLINICAL SCIENCE, Vol: 118, Pages: 565-572, ISSN: 0143-5221

Journal article

Hopkinson NS, Dayer MJ, Moxham J, Polkey MIet al., 2010, Abdominal muscle fatigue following exercise in chronic obstructive pulmonary disease, RESPIRATORY RESEARCH, Vol: 11

Journal article

Atallah L, Zhang J, Lo BPL, Shrikrishna D, Kelly JL, Jackson A, Polkey MI, Yang G, Hopkinson NSet al., 2010, Validation Of An Ear Worn Sensor For Activity Monitoring In COPD, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 181, ISSN: 1073-449X

Journal article

Lewis A, Riddoch-Contreras J, Natanek SA, Marsh GS, Polkey MI, Kemp PR, Hopkinson NSet al., 2010, Alterations in MRTF and FHL1 activity contribute to fibre type shift in the quadriceps of patients with COPD., Publisher: AMER THORACIC SOC, ISSN: 1073-449X

Conference paper

Lord VM, Cave P, Hume VJ, Flude EJ, Evans A, Kelly JL, Polkey MI, Hopkinson NSet al., 2010, Singing teaching as a therapy for chronic respiratory disease - a randomised controlled trial and qualitative evaluation, BMC PULMONARY MEDICINE, Vol: 10, ISSN: 1471-2466

Journal article

Hopkinson NS, Polkey MI, 2009, Chronic obstructive pulmonary disease in non-smokers., Lancet, Vol: 374

Journal article

Hopkinson NS, Polkey MI, 2009, Chronic obstructive pulmonary disease in non-smokers, LANCET, Vol: 374, Pages: 1964-1964, ISSN: 0140-6736

Journal article

Kelly JL, Mehta P, Shrikrishna D, Cramer D, Polkey MI, Hopkinson NSet al., 2009, EFFECT OF GOLD STAGE ON RATE OF DECLINE IN GAS TRANSFER AND SPIROMETRY IN COPD, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A159-A159, ISSN: 0040-6376

Conference paper

Mendoza L, Gogali A, Shrikrishna D, Kemp SV, Jackson AS, Shaikh ZF, Polkey MI, Wells AU, Hopkinson NSet al., 2009, QUADRICEPS ENDURANCE IS REDUCED IN FIBROTIC IDIOPATHIC INTERSTITIAL PNEUMONIA, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A44-A45, ISSN: 0040-6376

Conference paper

Lewis A, Sathyapala SA, Riddoch-Contreras J, Man WDC, Marsh GS, Polkey MI, Hopkinson NS, Kemp PRet al., 2009, REDUCED EXPRESSION AND ACTIVITY OF MYOCARDIN-RELATED TRANSCRIPTION FACTORS CONTRIBUTES TO FIBRE TYPE CHANGES IN THE QUADRICEPS OF PATIENTS WITH COPD, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A134-A134, ISSN: 0040-6376

Conference paper

Skipworth JRA, Raptis DA, Puthucheary Z, Rawal J, Shrikrishna D, Windsor J, Cramer D, Polkey MI, Montgomery HE, Hopkinson NSet al., 2009, THE EFFECT OF ACUTE HYPOXIA ON QT INTERVAL IN RESPIRATORY PATIENTS UNDERGOING FITNESS TO FLY TESTS, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A45-A46, ISSN: 0040-6376

Conference paper

Shrikrishna D, Kelly JL, Mendoza L, Jackson AS, Kemp SV, Lord V, Polkey MI, Hopkinson NSet al., 2009, MULTIPLE-FREQUENCY BIOELECTRICAL IMPEDANCE ANALYSIS AND QUADRICEPS STRENGTH IN PATIENTS WITH COPD, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A134-A134, ISSN: 0040-6376

Conference paper

Swallow EB, Barreiro E, Gosker H, Sathyapala SA, Sanchez F, Hopkinson NS, Moxham J, Schols A, Gea J, Polkey MIet al., 2009, Quadriceps muscle strength in scoliosis, EUROPEAN RESPIRATORY JOURNAL, Vol: 34, Pages: 1429-1435, ISSN: 0903-1936

Journal article

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