Publications
516 results found
Visca D, Fleming S, Firouzi A, et al., 2016, Randomised controlled, crossover trial to evaluate the effects of ambulatory oxygen on health status in patients with fibrotic lung disease, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Pereira M, Williams S, Restrick L, et al., 2016, Healthcare worker influenza vaccination is associated with reduced rates of sickness absence, EUROPEAN RESPIRATORY JOURNAL, Vol: 48, ISSN: 0903-1936
Garner J, Kemp SV, Toma TP, et al., 2016, Survival after endobronchial valve placement for emphysema: a 10-Year follow-up study, American Journal of Respiratory and Critical Care Medicine, Vol: 194, Pages: 519-521, ISSN: 1535-4970
Hopkinson NS, Millett C, Glantz S, et al., 2016, UK government should fund stop smoking media campaigns not give tax breaks to films with smoking imagery, Addiction, Vol: 111, Pages: 2066-2067, ISSN: 1360-0443
McNelly AS, Rawal J, Shrikrishna D, et al., 2016, An Exploratory Study of Long-Term Outcome Measures in Critical Illness Survivors: Construct Validity of Physical Activity, Frailty, and Health-Related Quality of Life Measures, Critical Care Medicine, Vol: 44, Pages: e362-e369, ISSN: 1530-0293
Objective: Functional capacity is commonly impaired after critical illness. We sought to clarify the relationship between objective measures of physical activity, self-reported measures of health-related quality of life, and clinician reported global functioning capacity (frailty) in such patients, as well as the impact of prior chronic disease status on these functional outcomes.Design: Prospective outcome study of critical illness survivors.Setting: Community-based follow-up.Patients: Participants of the Musculoskeletal Ultrasound Study in Critical Care: Longitudinal Evaluation Study (NCT01106300), invasively ventilated for more than 48 hours and on the ICU greater than 7 days.Interventions: None.Measurements and Main Results: Physical activity levels (health-related quality of life [36-item short-form health survey] and daily step counts [accelerometry]) were compared to norm-based or healthy control scores, respectively. Controls for frailty (Clinical Frailty Score) were non-morbid, age- and gender-matched to survivors. Ninety-one patients were recruited on ICU admission: 41 were contacted for post-discharge assessment, and data were collected from 30 (14 female; mean age, 55.3 yr [95% CI, 48.3–62.3]; mean post-discharge, 576 d [95% CI, 539–614]). Patients’ mean daily step count (5,803; 95% CI, 4,792–6,813) was lower than that in controls (11,735; 95% CI, 10,928–12,542; p < 0.001), and lower in those with preexisting chronic disease than without (2,989 [95% CI, 776–5,201] vs 7,737 [95% CI, 4,907–10,567]; p = 0.013). Physical activity measures (accelerometry, health-related quality of life, and frailty) demonstrated good construct validity across all three tools. Step variability (from SD) was highly correlated with daily steps (r2 = 0.67; p < 0.01) demonstrating a potential boundary constraint.Conclusions: Subjective and objective measures of physical activity are all informative in ICU survivors. They are all redu
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