Imperial College London
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ProfessorNickHopkinson

Faculty of Medicine, National Heart & Lung Institute

Professor of Respiratory Medicine
 
 
 
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Contact

 

n.hopkinson

 
 
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Location

 

Muscle LabSouth BlockRoyal Brompton Campus

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Summary

 

Publications

Citation

BibTex format

@article{Williams:2022:10.1136/bmjresp-2021-001030,
author = {Williams, P and Buttery, S and Mweseli, R and Phillip, KEJ and Sadaka, A and Bartlett, E and Devaraj, A and Kemp, S and Addis, J and Derbyshire, J and Chen, M and Morris, K and Laverty, A and Hopkinson, N},
doi = {10.1136/bmjresp-2021-001030},
journal = {BMJ Open Respiratory Research},
title = {Immediate smoking cessation support vs usual care in smokers attending a targeted lung health check; the QuLIT trial},
url = {http://dx.doi.org/10.1136/bmjresp-2021-001030},
volume = {9},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Objectives: Lung cancer screening programmes offer an opportunity to address tobacco dependence in current smokers. The effectiveness of different approaches to smoking cessation in this context has not yet been established. We investigated if immediate smoking cessation support, including pharmacotherapy, offered as part of a lung cancer screening programme, increases quit rates compared to usual care (Very Brief Advice to quit and signposting to smoking cessation services).Materials and Methods: We conducted a single-blind randomised controlled trial of current smokers aged 55-75 years attending a Targeted Lung Health Check (TLHC). On randomly allocated days smokers received either (1) immediate support from a trained smoking cessation counsellor with appropriate pharmacotherapy or (2) usual care. The primary outcome was self-reported quit rate at three months. We performed thematic analysis of participant interview responses.Results: Of 412 people attending between January and March 2020, 115(27.9%) were current smokers; 46% female, mean(SD) 62.4(5.3) years. Follow up data were available for 84 smokers. At 3 months quit rates in the intervention group were higher 14/48(29.2%) versus 4/36(11%) (2 3.98, p=0.04). Participant interviews revealed four smoking-cessation related themes; 1) Stress and anxiety, 2) Impact of the COVID-19 pandemic, 3) Computerised tomography scans influencing desire to quit, 4) Individual beliefs about stopping smoking.   Conclusion: The provision of immediate smoking cessation support is associated with a substantial increase in quit rates at three months. Further research is needed to investigate longer term outcomes and to refine future service delivery.
AU  - Williams,P
AU  - Buttery,S
AU  - Mweseli,R
AU  - Phillip,KEJ
AU  - Sadaka,A
AU  - Bartlett,E
AU  - Devaraj,A
AU  - Kemp,S
AU  - Addis,J
AU  - Derbyshire,J
AU  - Chen,M
AU  - Morris,K
AU  - Laverty,A
AU  - Hopkinson,N
DO  - 10.1136/bmjresp-2021-001030
PY  - 2022///
SN  - 2052-4439
TI  - Immediate smoking cessation support vs usual care in smokers attending a targeted lung health check; the QuLIT trial
T2  - BMJ Open Respiratory Research
UR  - http://dx.doi.org/10.1136/bmjresp-2021-001030
UR  - http://hdl.handle.net/10044/1/94517
VL  - 9
ER  -
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