Imperial College London
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ProfessorNickHopkinson

Faculty of Medicine, National Heart & Lung Institute

Professor of Respiratory Medicine
 
 
 
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Contact

 

n.hopkinson

 
 
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Location

 

Muscle LabSouth BlockRoyal Brompton Campus

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Summary

 

Publications

Citation

BibTex format

@article{Philip:2022:10.1016/S2213-2600(22)00125-4,
author = {Philip, KEJ and Owles, H and McVey, S and Pagnuco, T and Bruce, K and Brunjes, H and Banya, W and Mollica, J and Lound, A and Zumpe, S and Abrahams, AM and Padmanaban, V and Hardy, TH and Lewis, A and Lalvani, A and Elkin, S and Hopkinson, NS},
doi = {10.1016/S2213-2600(22)00125-4},
journal = {The Lancet Respiratory Medicine},
pages = {851--862},
title = {An online breathing and wellbeing programme (ENO Breathe) for people with persistent symptoms following COVID-19: a parallel-group, single-blind, randomised controlled trial},
url = {http://dx.doi.org/10.1016/S2213-2600(22)00125-4},
volume = {10},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BACKGROUND: There are few evidence-based interventions for long COVID; however, holistic approaches supporting recovery are advocated. We assessed whether an online breathing and wellbeing programme improves health related quality-of-life (HRQoL) in people with persisting breathlessness following COVID-19. METHODS: We conducted a parallel-group, single-blind, randomised controlled trial in patients who had been referred from one of 51 UK-based collaborating long COVID clinics. Eligible participants were aged 18 years or older; were recovering from COVID-19 with ongoing breathlessness, with or without anxiety, at least 4 weeks after symptom onset; had internet access with an appropriate device; and were deemed clinically suitable for participation by one of the collaborating COVID-19 clinics. Following clinical assessment, potential participants were given a unique online portal code. Participants were randomly assigned (1:1) to either immediate participation in the English National Opera (ENO) Breathe programme or to usual care. Randomisation was done by the research team using computer-generated block randomisation lists, with block size 10. The researcher responsible for randomisation was masked to responses. Participants in the ENO Breathe group participated in a 6-week online breathing and wellbeing programme, developed for people with long COVID experiencing breathlessness, focusing on breathing retraining using singing techniques. Those in the deferred group received usual care until they exited the trial. The primary outcome, assessed in the intention-to-treat population, was change in HRQoL, assessed using the RAND 36-item short form survey instrument mental health composite (MHC) and physical health composite (PHC) scores. Secondary outcome measures were the chronic obstructive pulmonary disease assessment test score, visual analogue scales (VAS) for breathlessness, and scores on the dyspnoea-12, the generalised anxiety disorder 7-item scale, and the short
AU  - Philip,KEJ
AU  - Owles,H
AU  - McVey,S
AU  - Pagnuco,T
AU  - Bruce,K
AU  - Brunjes,H
AU  - Banya,W
AU  - Mollica,J
AU  - Lound,A
AU  - Zumpe,S
AU  - Abrahams,AM
AU  - Padmanaban,V
AU  - Hardy,TH
AU  - Lewis,A
AU  - Lalvani,A
AU  - Elkin,S
AU  - Hopkinson,NS
DO  - 10.1016/S2213-2600(22)00125-4
EP  - 862
PY  - 2022///
SN  - 2213-2600
SP  - 851
TI  - An online breathing and wellbeing programme (ENO Breathe) for people with persistent symptoms following COVID-19: a parallel-group, single-blind, randomised controlled trial
T2  - The Lancet Respiratory Medicine
UR  - http://dx.doi.org/10.1016/S2213-2600(22)00125-4
UR  - https://www.ncbi.nlm.nih.gov/pubmed/35489367
UR  - https://www.sciencedirect.com/science/article/pii/S2213260022001254?via%3Dihub
UR  - http://hdl.handle.net/10044/1/96619
VL  - 10
ER  -
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