Imperial College London
Alternate

DrNesrinaImami

Faculty of Medicine, Department of Infectious Disease

Reader in Immunology
 
 
 
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Contact

 

+44 (0)20 3315 5987n.imami Website

 
 
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Location

 

I.2.8Chelsea and Westminster HospitalChelsea and Westminster Campus

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Summary

 

Publications

Citation

BibTex format

@article{Imami:2015:10.1080/21645515.2015.1021523,
author = {Imami, N and Herasimtschuk, AA},
doi = {10.1080/21645515.2015.1021523},
journal = {Human Vaccines & Immunotherapeutics},
pages = {2287--2293},
title = {Multifarious immunotherapeutic approaches to cure HIV-1 infection},
url = {http://dx.doi.org/10.1080/21645515.2015.1021523},
volume = {11},
year = {2015}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Immunotherapy in the context of treated HIV-1 infection aims to improve immune responses to achieve better control of the virus. To date, multifaceted immunotherapeutic approaches have been shown to reduce immune activation and increase CD4 T-lymphocyte counts, further to the effects of antiretroviral therapy alone, in addition to improving HIV-1-specific T-cell responses. While sterilizing cure of HIV-1 would involve elimination of all replication-competent virus, a functional cure in which the host has long-lasting control of viral replication may be more feasible. In this commentary, we discuss novel strategies aimed at targeting the latent viral reservoir with cure of HIV-1 infection being the ultimate goal, an achievement that would have considerable impact on worldwide HIV-1 infection.
AU  - Imami,N
AU  - Herasimtschuk,AA
DO  - 10.1080/21645515.2015.1021523
EP  - 2293
PY  - 2015///
SN  - 2164-5515
SP  - 2287
TI  - Multifarious immunotherapeutic approaches to cure HIV-1 infection
T2  - Human Vaccines & Immunotherapeutics
UR  - http://dx.doi.org/10.1080/21645515.2015.1021523
UR  - http://hdl.handle.net/10044/1/32979
VL  - 11
ER  -
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