Publications
73 results found
Higham CE, Atkinson AB, Aylwin S, et al., 2012, Effective Combination Treatment with Cabergoline and Low-Dose Pegvisomant in Active Acromegaly: A Prospective Clinical Trial, OBSTETRICAL & GYNECOLOGICAL SURVEY, Vol: 67, Pages: 475-476, ISSN: 0029-7828
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- Citations: 1
Popov N, Martin N, Aguilo F, et al., 2012, Homeobox Proteins Recruit Polycomb Repressive Complexes to Repress INK4a, 22nd Biennial Congress of the European-Association-for-Cancer-Research, Publisher: ELSEVIER SCI LTD, Pages: S62-S62, ISSN: 0959-8049
Ramachandran R, Bech P, Murphy KG, et al., 2012, Improved diagnostic accuracy for neuroendocrine neoplasms using two chromogranin A assays., Clin Endocrinol (Oxf), Vol: 76, Pages: 831-836
Chromogranin A (Cg A) is the best available diagnostic marker for neuroendocrine neoplasms (NENs). However, clinical interpretation of Cg A results may be limited by considerable heterogeneity between commonly available Cg A assays. Variation in diagnostic accuracy of these assays largely reflects differences in antibody specificities. We compared the diagnostic utility of four Cg A assays [Imperial Supra-regional Assay Service radioimmunoassay (SAS) and three commercial assays, Cisbio, DAKO and Eurodiagnostica].
Bech PR, Ramachandran R, Dhillo WS, et al., 2012, Quantifying the Effects of Renal Impairment on Plasma Concentrations of the Neuroendocrine Neoplasia Biomarkers Chromogranin A, Chromogranin B, and Cocaine- and Amphetamine-Regulated Transcript, CLINICAL CHEMISTRY, Vol: 58, Pages: 941-943, ISSN: 0009-9147
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- Citations: 31
Salem V, Hopkins TG, El-Gayar H, et al., 2012, Adrenal venous sampling as a diagnostic procedure for primary hyperaldosteronism: experience from a tertiary referral centre, HORMONES-INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM, Vol: 11, Pages: 151-159, ISSN: 1109-3099
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- Citations: 12
Higham CE, Atkinson AB, Aylwin S, et al., 2012, Effective Combination Treatment with Cabergoline and Low-Dose Pegvisomant in Active Acromegaly: A Prospective Clinical Trial, JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, Vol: 97, Pages: 1187-1193, ISSN: 0021-972X
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- Citations: 62
Ghourab S, Beale KE, Semjonous NM, et al., 2011, Intracerebroventricular administration of vasoactive intestinal peptide inhibits food intake, REGULATORY PEPTIDES, Vol: 172, Pages: 8-15, ISSN: 0167-0115
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- Citations: 15
Ford HE, Peters V, Martin NM, et al., 2011, Effects of oral ingestion of sucralose on gut hormone response and appetite in healthy normal-weight subjects, EUROPEAN JOURNAL OF CLINICAL NUTRITION, Vol: 65, Pages: 508-513, ISSN: 0954-3007
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- Citations: 131
Ramachandran R, Bech P, Murphy KG, et al., 2011, PLASMA GASTRIN: SOMATOSTATIN RATIO IS DECREASED IN GASTRINOMAS, Annual Meeting on British-Society-of-Gasenterology, Publisher: B M J PUBLISHING GROUP, Pages: A117-A117, ISSN: 0017-5749
Amin A, Carroll RW, Win Z, et al., 2011, New Imaging Modalities in the Diagnosis of Phaeochromocytoma, 8th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocine Tumor Disease, Publisher: KARGER, Pages: 14-14, ISSN: 0028-3835
Ramachandran R, Bech P, Murphy KG, et al., 2011, Plasma Somatostatin: Gastrin Ratio Improves the Diagnosis of Gastrinoma, 8th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocine Tumor Disease, Publisher: KARGER, Pages: 9-9, ISSN: 0028-3835
Bech P, Ramachandran R, Martin NM, et al., 2011, Chromogranin B Is a Prognostic Marker in NETs, 8th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocine Tumor Disease, Publisher: KARGER, Pages: 1-1, ISSN: 0028-3835
Amin A, Todd JF, Martin NM, et al., 2010, Catrinoid heart disease presenting in a patient undergoing Lutetium-177 DOTATATE therapy, 18th International Symposium on Regulatory Peptides, Publisher: ELSEVIER SCIENCE BV, Pages: 14-15, ISSN: 0167-0115
Ramachandran R, Bech P, Murphy KG, et al., 2010, Chromogranin A assays: Comparison of diagnostic accuracy, 18th International Symposium on Regulatory Peptides, Publisher: ELSEVIER SCIENCE BV, Pages: 12-12, ISSN: 0167-0115
Tan T, Cabrita IZ, Hensman D, et al., 2010, Assessment of cardiac valve dysfunction in patients receiving cabergoline treatment for hyperprolactinaemia, CLINICAL ENDOCRINOLOGY, Vol: 73, Pages: 369-374, ISSN: 0300-0664
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- Citations: 35
Field BCT, Wren AM, Peters V, et al., 2010, PYY<sub>3-36</sub> and Oxyntomodulin Can Be Additive in Their Effect on Food Intake in Overweight and Obese Humans, DIABETES, Vol: 59, Pages: 1635-1639, ISSN: 0012-1797
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- Citations: 87
Salem V, Dhillo WS, Meeran K, et al., 2010, Dexamethasone-Suppressed Corticotrophin-Releasing Hormone-Stimulation Test Does Not Reliably Diagnose or Predict Recurrence of Cushing Disease, CLINICAL CHEMISTRY, Vol: 56, Pages: 1031-1034, ISSN: 0009-9147
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- Citations: 6
Feeney CL, Meeran K, Hatfield E, et al., 2010, Complete Adrenal Failure Following Treatment of Cushing's Disease with Mitotane., 92nd Meeting and Expo of the Endocrine Society (ENDO 2010), Publisher: ENDOCRINE SOC, ISSN: 0163-769X
Leavy EM, Gardiner JV, Richardson E, et al., 2010, The Role of Neuropeptide Y within the Hypothalamic Dorsomedial Nucleus in the Regulation of Energy Homeostasis., 92nd Meeting and Expo of the Endocrine Society (ENDO 2010), Publisher: ENDOCRINE SOC, ISSN: 0163-769X
Ramachandran R, Benfield P, Dhillo WS, et al., 2009, Need for Revision of Diagnostic Limits for Medullary Thyroid Carcinoma with a New Immunochemiluminometric Calcitonin Assay, CLINICAL CHEMISTRY, Vol: 55, Pages: 2225-2226, ISSN: 0009-9147
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- Citations: 5
Jayasena CN, Gadhvi KA, Gohel B, et al., 2009, Day 5 Morning Serum Cortisol Predicts Hypothalamic-Pituitary-Adrenal Function after Transsphenoidal Surgery for Pituitary Tumors, CLINICAL CHEMISTRY, Vol: 55, Pages: 972-977, ISSN: 0009-9147
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- Citations: 35
Banerjee A, Wynne K, Tan T, et al., 2009, High dose cabergoline therapy for a resistant macroprolactinoma during pregnancy, CLINICAL ENDOCRINOLOGY, Vol: 70, Pages: 812-813, ISSN: 0300-0664
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- Citations: 7
Martin NM, Tan T, Meeran K, 2009, Dopamine agonists and hyperprolactinaemia, BRITISH MEDICAL JOURNAL, Vol: 338, ISSN: 0959-8146
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- Citations: 6
Simpson KA, Martin NM, Bloom SR, 2009, Hypothalamic regulation of food intake and clinical therapeutic applications, ARQUIVOS BRASILEIROS DE ENDOCRINOLOGIA E METABOLOGIA, Vol: 53, Pages: 120-128, ISSN: 0004-2730
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- Citations: 93
Martin NM, Meeran K, Bloom SR, 2009, Glucagonomas, Clinical Endocrine Oncology: Second Edition, Pages: 474-478, ISBN: 9781405145848
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- Citations: 2
Tan TM, Hatfield EC, Thakker RV, et al., 2009, A legacy of tinnitus: multiple head and neck paragangliomas., Rare Tumors, Vol: 1, Pages: 88-89, ISSN: 2036-3605
We describe the case of a patient who presented with a right-sided glomus jugulare tumor and bilateral glomus vagale tumors. These proved to be nonmalignant paragangliomas on histopathological analysis. Genetic analysis revealed a germline heterozygous missense mutation (Pro81Leu) in the succinate dehydrogenase subunit D (SDHD) gene. We discuss the clinical presentations of the familial paraganglioma syndrome type 1, which is caused by mutations in SDHD, and the implications for the clinical diagnosis and care of such patients.
Smith KL, Gardiner JV, Ward HL, et al., 2008, Overexpression of CART in the PVN increases food intake and weight gain in rats, OBESITY, Vol: 16, Pages: 2239-2244, ISSN: 1930-7381
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- Citations: 38
Simpson KA, Martin NM, Bloom SR, 2008, Hypothalamic regulation of appetite., Expert Rev Endocrinol Metab, Vol: 3, Pages: 577-592
The prevalence of obesity is steadily rising and has huge health and financial implications for society. Weight gain is due to an imbalance between dietary intake and energy expenditure and research has focused on trying to understand the complex pathways involved in controlling these aspects. This review highlights the key areas of research in the hypothalamic control of appetite. The hypothalamus consists of several nuclei that integrate peripheral signals, such as adiposity and caloric intake, to regulate important pathways within the CNS controlling food intake. The best characterized pathways are the orexigenic neuropeptide Y/Agouti-related protein and the anorexigenic pro-opiomelanocortin/cocaine- and amphetamine-related transcript neurons in the arcuate nucleus of the hypothalamus. These project from the arcuate nucleus to other key hypothalamic nuclei, such as the paraventricular, dorsomedial, ventromedial and lateral hypothalamic nuclei. There are also projections to and from the brainstem, cortical areas and reward pathways, all of which influence food intake. The challenge at present is to understand the complexity of these pathways and try to find ways of modulating them in order to find potential therapeutic targets.
Winstanley V, Little MA, Wadsworth C, et al., 2008, The McKittrick-Wheelock syndrome: A case of acute renal failure due to neoplastic cholera, RENAL FAILURE, Vol: 30, Pages: 469-473, ISSN: 0886-022X
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- Citations: 9
Martin NM, Dhillo WS, Meeran K, 2007, The dexamethasone-suppressed corticotropin-releasing hormone stimulation test and the desmopressin test to distinguish Cushing's syndrome from pseudo-Cushing's states, CLINICAL ENDOCRINOLOGY, Vol: 67, Pages: 476-476, ISSN: 0300-0664
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- Citations: 4
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