Imperial College London

ProfessorNicholasMazarakis

Faculty of MedicineDepartment of Brain Sciences

Chair MolBioMedicine and Head of Gene Therapy
 
 
 
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Contact

 

+44 (0)20 7594 7024n.mazarakis Website

 
 
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Assistant

 

Mrs Hadeel Abdeen +44 (0)20 7594 7014

 
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Location

 

E402Burlington DanesHammersmith Campus

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Summary

 

Publications

Publication Type
Year
to

131 results found

Azzouz M, Le T, Ralph SG, Wilkes F, Burghes AH, Kingsman SM, Mitrophanous KA, Mazarakis NDet al., 2004, VEGF gene therapy with retrogradely transported lentivirus prolongs survival in mouse ALS model, 7th Annual Meeting of the American-Society-of-Gene-Therapy, Publisher: ACADEMIC PRESS INC ELSEVIER SCIENCE, Pages: S200-S200, ISSN: 1525-0016

Conference paper

Themis M, Gregory LG, Waddington SN, Holder MV, Mitrophanous KA, Buckley SMK, Bigger BW, Ellard FE, Walmsley LE, Radcliff P, Mazarakis N, Azzouz M, Lawrence L, Cook T, Allaf FA, Kingsman S, Coutelle Cet al., 2004, The fetal approach: A novel therapy for the treatment of musculo-skeletal disease, 7th Annual Meeting of the American-Society-of-Gene-Therapy, Publisher: ACADEMIC PRESS INC ELSEVIER SCIENCE, Pages: S91-S91, ISSN: 1525-0016

Conference paper

Tanase D, Teng QS, Krishnaney AA, Liu JK, Garrity-Moses ME, Mazarakis N, Walmsley LE, Azzouz M, Boulis NMet al., 2004, Cervical spinal cord delivery of a lentiviral vector in SOD-1 transgenic mice, 7th Annual Meeting of the American-Society-of-Gene-Therapy, Publisher: ACADEMIC PRESS INC ELSEVIER SCIENCE, Pages: S201-S201, ISSN: 1525-0016

Conference paper

Miller TW, Wolfgang WJ, Manley K, Zhou YS, Zhou C, Webster JM, Mazarakis ND, Messer Aet al., 2004, <i>In vivo</i> and <i>in situ</i> delivery of huntingtin-specific single-chain Fv intrabody genes as therapeutic agents for Huntington's disease, 7th Annual Meeting of the American-Society-of-Gene-Therapy, Publisher: ACADEMIC PRESS INC ELSEVIER SCIENCE, Pages: S20-S21, ISSN: 1525-0016

Conference paper

Wong LF, Azzouz M, Walmsley LE, Askham Z, Wilkes FJ, Mitrophanous KA, Kingsman SM, Mazarakis NDet al., 2004, Transduction patterns of pseudotyped lentiviral vectors in the nervous system (vol 9, pg 101, 2003), MOLECULAR THERAPY, Vol: 9, Pages: 765-765, ISSN: 1525-0016

Journal article

Wong LF, Yip PK, Battaglia A, Grist J, Walmsley LE, Maden M, Kingsman SM, Kingsman AJ, McMahon SB, Mazarakis NDet al., 2004, Regenerative properties of retinoic acid receptor β2 in rat model of dorsal rhizotomy, 7th Annual Meeting of the American-Society-of-Gene-Therapy, Publisher: ACADEMIC PRESS INC ELSEVIER SCIENCE, Pages: S80-S80, ISSN: 1525-0016

Conference paper

Bienemann A, Radcliffe P, Mitrophanous K, Glover C, Mazarakis N, Uney Jet al., 2004, Reversal of hypothalamic diabetes insipidus using EIAV-based regulatable lentiviral vectors expressing arginine vasopressin, 7th Annual Meeting of the American-Society-of-Gene-Therapy, Publisher: ACADEMIC PRESS INC ELSEVIER SCIENCE, Pages: S241-S241, ISSN: 1525-0016

Conference paper

Azzouz M, Ralph S, Wong LF, Day D, Askham Z, Barber RD, Mitrophanous KA, Kingsman SM, Mazarakis NDet al., 2004, Neuroprotection in a rat Parkinson model by GDNF gene therapy using EIAV vector, NEUROREPORT, Vol: 15, Pages: 985-990, ISSN: 0959-4965

Journal article

Ralph GS, Parham S, Lee SR, Beard GL, Craigon MH, Ward N, White JR, Barber RD, Rayner W, Kingsman SM, Mundy CR, Mazarakis ND, Krige Det al., 2004, Identification of potential stroke targets by lentiviral vector mediated overexpression of HIF-1α and HIF-2α in a primary neuronal model of hypoxia, JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, Vol: 24, Pages: 245-258, ISSN: 0271-678X

Journal article

Wong LF, Azzouz M, Walmsley LE, Askham Z, Wilkes FJ, Mitrophanous KA, Kingsman SM, Mazarakis NDet al., 2004, Transduction patterns of pseudotyped lentiviral vectors in the nervous system, MOLECULAR THERAPY, Vol: 9, Pages: 101-111, ISSN: 1525-0016

Journal article

Azzouz M, Ralph S, Storkebaum E, Mitrophanous K, Kingsman S, Carmeliet P, Mazarakis Net al., 2004, VEGF gene therapy with retrogradely transported lentivector prolongs survival in a mouse ALS model, J Neurochem, Vol: 90, Pages: 55-55

Journal article

Tanase D, Garrity-Moses ME, Liu JK, Teng QS, Mazarakis ND, Boulis NMet al., 2003, Techniques for remote cervical spinal cord delivery of neurotherapeutic RabG-EIAV encoded genes, 6th Annual Meeting of the American-Society-of-Gene-Therapy, Publisher: ACADEMIC PRESS INC ELSEVIER SCIENCE, Pages: S97-S97, ISSN: 1525-0016

Conference paper

Buehler B, Driver DA, Reed JD, Brin E, Greengard JS, Mitrophanous KA, Mazarakis ND, Jolly DJ, Rohll JBet al., 2003, Optimization of lentiviral EIAV tricistronic vectors for Parkinson's disease gene therapy, 6th Annual Meeting of the American-Society-of-Gene-Therapy, Publisher: ACADEMIC PRESS INC ELSEVIER SCIENCE, Pages: S343-S343, ISSN: 1525-0016

Conference paper

Bienemann AS, Martin-Rendon E, Cosgrave AS, Glover CPJ, Wong LF, Kingsman SM, Mitrophanous KA, Mazarakis ND, Uney JBet al., 2003, Long-term replacement of a mutated nonfunctional CNS gene: Reversal of hypothalamic diabetes insipidus using an EIAV-based lentiviral vector expressing arginine vasopressin, MOLECULAR THERAPY, Vol: 7, Pages: 588-596, ISSN: 1525-0016

Journal article

Azzouz M, Le TN, Waddington S, Walmsley L, Monani U, Wilkes FJ, Themis M, Mitrophanous KA, Burghes A, Mazarakis NDet al., 2003, Lentiviral vector-mediated gene therapy for a mouse model of spinal muscular atrophy, 6th Annual Meeting of the American-Society-of-Gene-Therapy, Publisher: ACADEMIC PRESS INC ELSEVIER SCIENCE, Pages: S248-S248, ISSN: 1525-0016

Conference paper

Azzouz M, Martin-Rendon E, Barber RD, Mitrophanous KA, Carter EE, Rohll JB, Kingsman SM, Kingsman AJ, Mazarakis NDet al., 2002, Multicistronic lentiviral vector-mediated striatal gene transfer of aromatic L-amino acid decarboxylase, tyrosine hydroxylase, and GTP cyclohydrolase I induces sustained transgene expression, dopamine production, and functional improvement in a rat model of Parkinson's disease., JOURNAL OF NEUROSCIENCE, Vol: 22, Pages: 10302-10312, ISSN: 0270-6474

Journal article

Corcoran J, So PL, Barber RD, Vincent KJ, Mazarakis ND, Mitrophanous KA, Kingsman SM, Maden Met al., 2002, Retinoic acid receptor β2 and neurite outgrowth in the adult mouse spinal cord in vitro, JOURNAL OF CELL SCIENCE, Vol: 115, Pages: 3779-3786, ISSN: 0021-9533

Journal article

Martin-Rendon E, White LJ, Olsen A, Mitrophanous KA, Mazarakis NDet al., 2002, New methods to titrate EIAV-based lentiviral vectors, MOLECULAR THERAPY, Vol: 5, Pages: 566-570, ISSN: 1525-0016

Journal article

Azzouz M, Martin-Rendon E, Barber RD, Blakemore W, Carter E E, Ellard F M, Rohll J B, Olsen A, Mitrophanous K A, Kingsman S M, Mazarakis N Det al., 2002, Functional Rescue of Parkinsonian Rats by Dopamine Replacement Using a multicistronic Lentiviral Vector, Clin Neuropath, Vol: 21, Pages: 175-175

Journal article

Rohll JB, Mitrophanous KA, Martin-Rendon E, Ellard FM, Radcliffe PA, Mazarakis ND, Kingsman SMet al., 2002, Design, production, safety, evaluation, and clinical applications of nonprimate lentiviral vectors, GENE THERAPY METHODS, Vol: 346, Pages: 466-500, ISSN: 0076-6879

Journal article

Bienemann AS, Martin Rendon E, Cosgrave A, Mitrophanous K, Mazarakis N, Uney JBet al., 2002, Long-term reversal of hypothalamic diabetes insipidus using lentiviral gene transfer, Mol Ther, Vol: 5, Pages: S280-S280

Journal article

Martin-Rendon E, Azzouz M, Barber RD, Blakemore W, Carter E E, Ellard F M, Rohll J B, Olsen A, Mitrophanous K A, Kingsman S M, Mazarakis N Det al., 2002, Functional Rescue of Parkinsonian Rats by Dopamine Replacement Using a multicistronic Lentiviral Vector, Mol Ther, Vol: 5, Pages: S247-S247

Journal article

Ralph S, Parham S, Krige D, Barber R, Mazarakis N, Kingsman S, Mundy Cet al., 2002, Identification of novel stroke targets using ‘SMARTOMICS’ strategies, Mol Ther, Vol: 5, Pages: S100-S100

Journal article

Martin-Rendon E, Azzouz M, Mazarakis ND, 2001, Lentiviral vectors for the treatment of neurodegenerative diseases, CURRENT OPINION IN MOLECULAR THERAPEUTICS, Vol: 3, Pages: 476-481, ISSN: 1464-8431

Journal article

Mazarakis ND, Azzouz M, Rohll JB, Ellard FM, Wilkes FJ, Olsen AL, Carter EE, Barber RD, Baban DF, Kingsman SM, Kingsman AJ, O'Malley K, Mitrophanous KAet al., 2001, Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral delivery, HUMAN MOLECULAR GENETICS, Vol: 10, Pages: 2109-2121, ISSN: 0964-6906

Journal article

Mitrophanous KA, Ellard FM, Rohll JB, Barber RD, Martin-Rendon E, Wilkes FJ, Griffiths L, Carter EE, Esapa M, Chipchase D, Walmsley L, Baban D, Olsen AL, Mazarakis ND, Kingsman SMet al., 2001, Generation of an EIAV based lentiviral producer cell line utilising a codon-optimised gag/pol gene., Mol Ther, Vol: 3, Pages: S330-S330

Journal article

Baban DF, Rohll JB, Ellard FM, Barber RD, Wikes F, Azzouz M, Martin-Rendon E, Kingsman SM, Mazarakis N, Mitrophanous KAet al., 2001, Production of EIAV based lentiviral vectors for gene therapy., Eur J Cancer, Vol: 37, Pages: S147-S147

Journal article

Kingsman S, Martin-Rendon E, Azzouz M, Rohll JB, Olsen A, Carter EE, Mitrophanous KA, Mazarakis NDet al., 2001, Lentiviral EIAV vectors for gene therapy of Parkinson’s disease, Mol Ther, Vol: 3, Pages: S330-S330

Journal article

Martin-Rendon E, Rohll JB, Barber RD, Olsen A, Dove L, Slade A, Kingsman SM, Mitrophanous KA, Mazarakis NDet al., 2001, New Methods for determining titers of EIAV vectors, Mol Ther, Vol: 3, Pages: S331-S331

Journal article

Jouvet P, Rustin P, Taylor DL, Pocock JM, Felderhoff-Mueser U, Mazarakis ND, Sarraf C, Joashi U, Kozma M, Greenwood K, Edwards AD, Mehmet Het al., 2000, Branched chain amino acids induce apoptosis in neural cells without mitochondrial membrane depolarization or cytochrome <i>c</i> release:: Implications for neurological impairment associated with maple syrup urine disease, MOLECULAR BIOLOGY OF THE CELL, Vol: 11, Pages: 1919-1932, ISSN: 1059-1524

Journal article

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