Collaborators
Jesse McClean and Ole Isacsoon, McLean Hospital / Harvard University, 2011
Dr Argyro Sgourou, School of Science and Technology, Hellenic Open University, Patras Greece, 2011
Dr Evanthia Galanis, Mayo Clinic, Rochester Minnesota USA, 2010
Professor Giampietro Schiavo, Cancer Research UK London Research Institute, 2009
Dr Alla Karpova, HHMI/Janelia Farm Research Campus, 2007
Guest Lectures
“Towards gene therapy for a neurodevelopmental disorder: AAV gene replacement therapy in models of cdkl5 disorder” May 17-18, 2019, Hellenic Society of Gene Therapy and Regenerative Medicine, Athens, Greece, 2019
“Viral vectors for gene therapy and modelling of CNS diseases”, 27th Annual meeting of the network of European Transplantation & Restoration (NECTAR), Dublin Ireland, 2017
“Selective vs widespread CNS gene transfer with viral vectors”, BSGCT Annual Conference, Cardiff, 2017
Harnessing viruses for gene therapy and modelling of neurological diseases, The Hellenic Medical Society, Hellenic Centre London, 2016
PGC-1α overexpression by lentiviral vector attenuates amyloid-β load and neuronal loss in an Alzheimer’s disease model, European Society of Gene & Cell Therapy Congress, Florence Italy, 2016
Neuroprotection in an ALS mouse model following peripheral delivery of motor neuron targeted aCAR-IGF-1 Lentiviral vector, ESGCT Congress, Finlandia Hall Helsinki Finland, 2015
AAV Vector Gene Therapy for Parkinson's Disease, Department of Experimental Medical Science, Faculty of Medicine, Lund University, Sweden, 2014
Lentiviral Vectors: Clinical Trials for Neurodegenerative Diseases., Division of Brain Sciences seminar, Imperial College London, 2014
“Gene-based Therapeutics for Neurological Disorders: From Basic Science to Clinical Applications” Fusion Conference Plenary lecture: Lentiviral Vectors: Prospect for Clinical Gene Therapy, Cancun Mexico, 2014
Lentiviral vector based gene therapy in the fight against neurodegenerative diseases, 1st International Multithematic Medical Congress "Bio-Medical Scientific Cyprus",School of Medicine, European University of Cyprus, Nicosia, Cyprus, 2013
Thy1.1, p75NTR or CAR receptor targeting by lentiviral vectors leads to retrograde transport and transduction of spinal motor neurons following peripheral delivery., ESGCT/SETGC collaborative Congress, Madrid, Spain, 2013
Challenges in Translational Medicine TRANSMED Conference"Translational gene therapy approaches for neurodegenerative diseases using lentiviral vectors", Biomedical Research Foundation of the Academy of Athens, Athens Greece, 2013
Gene Therapy Approaches for Parkinson’s Disease,, Mitchell Lewis Seminar Series, Department of Haematology Imperial College Faculty of Medicine, London, 2012
Gene Therapy for Parkinson’s Disease., Neuroméditerranée XII Congress, Institute of Neurology, Paphos Cyprus, 2012
Gene Therapy for Parkinson’s Disease., Academic Neuroscience Guest Lecture, Charing Cross Hospital, 2012
Gene Therapy for Parkinson’s Disease, Cambridge Neurological Society, Addenbrooke’s Hospital Cambridge, 2012
Enhanced pseudotyping efficiency of HIV-1 lentiviral vectors by a rabies/Vesicular stomatitis virus chimeric envelope glycoprotein, European Society of Gene and Cell Therapy & British Society for Gene Therapy Collaborative Congress, Brighton Centre, Brighton, 2011
Viral vectors: research and clinical applications in neurodegenerative diseases and cancer, Inaugural Lecture, Division of Experimental Medicine, Imperial College London, Hammersmith Campus, 2010
Update on current clinical trials: unlocking the potential of Gene Therapy for the treatment of Parkinson's disease., 12th national conference on Parkinson’s, Dexter House, London, 2010
Current Advances in Gene Therapy for Parkinson’s disease., 6th Panhellenic Congress of Pharmacology, Faculty of Medicine University of Crete Heraklion Greece, 2010
Use of AAV and Lentivirus as therapeutic tools for neurodegenerative diseases, European Brain Research InstituteENINET worksop on "Virus based techologies for investigating function & pathology of the nervous system", Rome Italy, 2009
Lentiviral Vectors for Gene Therapy of CNS Diseases, Mayo Clinic, Rochester USA, 2007
Lentiviral Vectors for Gene Delivery to the Parkinsonian Striatum, NINDS Workshop on Gene Delivery to the Nervous System, Washington DC USA, 2007
Gene Therapy of Neurological Disorders, 14th Annual Congress of the European Society of Gene Therapy (ESGT), Athens Greece, 2006
Lentiviral Gene Therapy for CNS disorders, Plenary Lecture: 8th International Conference on Drug and Gene-based Therapeutics, Crete Greece, 2006
Treatment of ALS and SMA Using Lentiviral Mediated Gene Transfer of VEGF and SMN-1, 9th Annual ASGT Meeting, Baltimore USA, 2006
Functional Regeneration of Injured Axons into Adult Spinal Cord by Lentivector® -mediated Delivery of Retinoic Acid Receptor-beta2 to Dorsal Root Ganglion Neurones, 3rd BSGT Annual Meeting, Imperial College London, 2006
Lentiviral vectors in the CNS: Gene Therapy and Research Applications, Sapienza University, Rome Italy, 2006
Research Staff
James,R
Taylor,H
Trabalza,A
Research Student Supervision
Eleftheriadou,I, Development of Novel Targeted Lentiviral Vectors for Gene Therapy of Motor Neuron Diseases
Hiraide,R, Investigation of CNS tropism of lentiviral vectors pseudotyped with envelope glycoporotein from a neurovirulant sindbis virus
Islam T,, Characterisation of Retrograde Trafficking Routes Used by Rabies Glycoprotein Pseudotyped Lentiviral Vectors