Imperial College London
Dr Nazima Pathan

DrNazimaPathan

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Honorary Clinical Senior Lecturer
 
 
 
//

Contact

 

n.pathan

 
 
//

Location

 

PICURoyal BromptonRoyal Brompton Campus

//

Summary

 

Publications

Citation

BibTex format

@article{De:2010:10.1097/PCC.0b013e3181ce7465,
author = {De, Wit B and Meyer, R and Desai, A and Macrae, D and Pathan, N},
doi = {10.1097/PCC.0b013e3181ce7465},
journal = {Pediatr Crit Care Med},
pages = {496--501},
title = {Challenge of predicting resting energy expenditure in children undergoing surgery for congenital heart disease},
url = {http://dx.doi.org/10.1097/PCC.0b013e3181ce7465},
volume = {11},
year = {2010}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - OBJECTIVES: To determine pre- and postoperative predictors of energy expenditure in children with congenital heart disease requiring open heart surgery; and to compare measured resting energy expenditure with current predictive equations. DESIGN: Prospective resting energy expenditure data were collected, using indirect calorimetry, for ventilated children admitted consecutively to the pediatric intensive care unit after surgery for congenital heart disease. A 30-min steady-state measurement was performed in suitable patients. Resting energy expenditure was compared to pre- and postoperative clinical variables, and to predicted energy expenditure, using currently used predictive equations. SETTING: Pediatric intensive care unit at the Royal Brompton Hospital, London. PATIENTS: Children ventilated in the pediatric intensive care unit post surgery for congenital heart disease. INTERVENTIONS: Measurement of energy expenditure by indirect calorimetry. MEASUREMENTS AND MAIN RESULTS: Twenty-one mechanically ventilated children (n = 17 boys, 4 girls) were enrolled in the study. Mean +/- sd measured resting energy expenditure was 67.8 +/- 15.4 kcal/kg/day. Most children had inadequate delivery of nutrients compared with actual requirements. Cardiopulmonary bypass had a significant influence on energy expenditure after surgery; in patients who underwent cardiopulmonary bypass during surgery, mean resting energy expenditure was 73.6 +/- 14.45 kcal/kg/day vs. 58.3 +/- 10.29 kcal/kg/day in patients undergoing nonbypass surgery. Children who were malnourished preoperatively had greater resting energy expenditure postoperatively. There was also a significant difference between measured energy expenditure and the Schofield (p = .006), World Health Organization (p = .002), and pediatric intensive care unit-specific formula (p < .0001). However, energy expenditure or a relative energy deficit in the early postoperative period was not associated with severity or duration of organ
AU  - De,Wit B
AU  - Meyer,R
AU  - Desai,A
AU  - Macrae,D
AU  - Pathan,N
DO  - 10.1097/PCC.0b013e3181ce7465
EP  - 501
PY  - 2010///
SN  - 1529-7535
SP  - 496
TI  - Challenge of predicting resting energy expenditure in children undergoing surgery for congenital heart disease
T2  - Pediatr Crit Care Med
UR  - http://dx.doi.org/10.1097/PCC.0b013e3181ce7465
VL  - 11
ER  -
Download