Summary
Nathan Peiffer-Smadja is a doctor specialized in Internal Medicine and Infectious Diseases and holds a PhD in Public Health.He is a Honorary Clinical Research Fellow at Imperial College London in the National Institute of Health Research (NIHR) Health Protection Research Unit in Healthcare Associated Infections and AMR and a research associate in the Inserm Infection, Antimicrobials, Modelling, Evolution (IAME) laboratory. He works as an Associate Professor in the Infectious and Tropical Diseases Department at the Bichat - Claude Bernard Academic Hospital, AP-HP, Paris, France.
His research focuses on the interface between electronic clinical decision support systems (CDSS) and implementation science, used in order to improve the day-to-day clinical management of infectious diseases, tropical diseases and emerging diseases. He has 8 years of clinical experience in French teaching hospitals and 4 years of experience in clinical research, mainly on the ways to optimize the use of antibiotics and in improving the treatment of COVID-19.
Selected publications
Antimicrobial stewardship
- Ahuja S, Peiffer-Smadja N, et al. Use of Feedback Data to Reduce Surgical Site Infections and Optimize Antibiotic Use in Surgery: A Systematic Scoping Review. Annals of Surgery, 2021
- Peiffer-Smadja N, et al. Performance and impact of a multiplex PCR in ICU patients with ventilator-associated pneumonia or ventilated hospital-acquired pneumonia. Critical Care, 2020
- Peiffer-Smadja N, et al. Paving the way for the implementation of a decision support system for antibiotic prescribing in primary care in West Africa: assessing contextual relevance and fit. Journal of Medical Internet Research, 2020
- Peiffer-Smadja N, et al. Preventing and Managing Urinary Tract Infections: Enhancing the Role of Community Pharmacists-A Mixed Methods Study. Antibiotics (Basel), 2020
- Peiffer-Smadja N, et al. Machine learning in the clinical microbiology laboratory: has the time come for routine practice? Clinical Microbiology and Infection, 2020
- Peiffer-Smadja N, et al. Machine learning for clinical decision support in infectious diseases: A narrative review of current applications. Clinical Microbiology and Infection, 2019
COVID-19
- Peiffer-Smadja N et al. Emergence of E484K Mutation Following Bamlanivimab Monotherapy among High-Risk Patients Infected with the Alpha Variant of SARS-CoV-2. Viruses, 2021
- Fiolet T, Kherabi Y, MacDonald CJ, Ghosn J, Peiffer-Smadja N. Comparing COVID-19 vaccines for their characteristics, efficacy and effectiveness against SARS-CoV-2 and variants of concern: a narrative review. Clinical Microbiology and Infection, 2021
- Ader F, Bouscambert-Duchamp M, Hites M, Peiffer-Smadja N, et al. Remdesivir plus standard of care versus standard of care alone for the treatment of patients admitted to hospital with COVID-19 (DisCoVeRy): a phase 3, randomised, controlled, open-label trial. Lancet Infectious Diseases, 2021
- Ader F, Peiffer-Smadja N et al. An open-label randomized controlled trial of the effect of lopinavir/ritonavir, lopinavir/ritonavir plus IFN-β-1a and hydroxychloroquine in hospitalized patients with COVID-19. Clinical Microbiology and Infection, 2021
- Peiffer-Smadja N, et al. Anticovid, a comprehensive open-access real-time platform of registered clinical studies for COVID-19. Journal of Antimicrobial Chemotherapy, 2020
- Meppiel E, Peiffer-Smadja N et al. Neurological manifestations associated with COVID-19: a multicentric registry. Clinical Microbiology and Infection, 2020
Publications
Journals
Terzić V, Miantezila Basilua J, Billard N, et al., 2024, Cardiac Adverse Events and Remdesivir in Hospitalized Patients with Coronavirus Disease 2019 (COVID-19): A Post Hoc Safety Analysis of the Randomized DisCoVeRy Trial., Clin Infect Dis
Bertin C, Tarhini H, Rahi M, et al., 2023, Complicated scarring following mpox infection, British Journal of Dermatology, Vol:189, ISSN:0007-0963, Pages:225-226
Dagenais C, Kielende M, Coulibaly A, et al., 2023, Lessons Learned from Field Experiences on Hospitals' Resilience to the COVID-19 Pandemic: A Systematic Approach, Health Systems & Reform, Vol:9, ISSN:2328-8604
Bertin C, Beaumont A-L, Merlant M, et al., 2023, Erythematous maculopapular rash in monkeypox virus infection: A retrospective case series of 30 patients, Journal of the European Academy of Dermatology and Venereology, Vol:37, ISSN:0926-9959, Pages:E638-E641
Beaumont A-L, Rozencwajg S, Peiffer-Smadja N, et al., 2023, COVID-19: Brief overview of therapeutic strategies., Anaesth Crit Care Pain Med, Vol:42