Imperial College London
Dr Nicholas Penney

DrNicholasPenney

Faculty of Medicine, Department of Surgery & Cancer

Honorary Clinical Research Fellow
 
 
 
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Contact

 

n.penney

 
 
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Location

 

Queen Elizabeth the Queen Mother Wing (QEQM)St Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Yeung:2020:10.1097/SLA.0000000000003275,
author = {Yeung, KTD and Penney, N and Ashrafian, L and Darzi, A and Ashrafian, H},
doi = {10.1097/SLA.0000000000003275},
journal = {Annals of Surgery},
pages = {257--265},
title = {Does sleeve gastrectomy expose the distal esophagus to severe reflux?: A systematic review and meta-analysis},
url = {http://dx.doi.org/10.1097/SLA.0000000000003275},
volume = {271},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - MINI: The reported prevalence of new-onset or worsening gastroesophageal reflux disease after sleeve gastrectomy is controversial. Subsequent esophagitis and Barrett's esophagus can be serious unintended sequalae. The aim of this study was to systematically appraise all existing published data to assess the effect of sleeve gastrectomy on gastroesophageal reflux, esophagitis, and Barrett's esophagus. OBJECTIVE: The aim of this study was to appraise the prevalence of gastroesophageal reflux disease (GERD), esophagitis, and Barrett's esophagus (BE) after sleeve gastrectomy (SG) through a systematic review and meta-analysis. BACKGROUND: The precise prevalence of new-onset or worsening GERD after SG is controversial. Subsequent esophagitis and BE can be a serious unintended sequalae. Their postoperative prevalence remains unclear. METHODS: A systematic literature search was performed to identify studies evaluating postoperative outcomes in primary SG for morbid obesity. The primary outcome was prevalence of GERD, esophagitis, and BE after SG. Meta-analysis was performed to calculate combined prevalence. RESULTS: A total of 46 studies totaling 10,718 patients were included. Meta-analysis found that the increase of postoperative GERD after sleeve (POGAS) was 19% and de novo reflux was 23%. The long-term prevalence of esophagitis was 28% and BE was 8%. Four percent of all patients required conversion to RYGB for severe reflux. CONCLUSIONS: The postoperative prevalence of GERD, esophagitis, and BE following SG is significant. Symptoms do not always correlate with the presence of pathology. As the surgical uptake of SG continues to increase, there is a need to ensure that surgical decision-making and the consent process for this procedure consider these long-term complications while also ensuring their postoperative surveillance through endoscopic and physiological approaches. The long-term outcomes of this commonly performed bariatric procedure should be considered alongsid
AU  - Yeung,KTD
AU  - Penney,N
AU  - Ashrafian,L
AU  - Darzi,A
AU  - Ashrafian,H
DO  - 10.1097/SLA.0000000000003275
EP  - 265
PY  - 2020///
SN  - 0003-4932
SP  - 257
TI  - Does sleeve gastrectomy expose the distal esophagus to severe reflux?: A systematic review and meta-analysis
T2  - Annals of Surgery
UR  - http://dx.doi.org/10.1097/SLA.0000000000003275
UR  - https://www.ncbi.nlm.nih.gov/pubmed/30921053
UR  - http://hdl.handle.net/10044/1/68203
VL  - 271
ER  -
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