Imperial College London

Dr Natalie C Butterfield

Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Research Associate



+44 (0)20 3313 8432natalie.butterfield Website




10N2Commonwealth BuildingHammersmith Campus





Post-doctoral researcher.

Molecular Endocrinology Laboratory (Professors Graham Williams & Duncan Bassett)

Natalie leads the joint phenotyping pipeline of the Origins of Bone and Cartilage Disease Project (OBCD)


Member of the ECTS Academy (     Image result for ECTS ACADEMy logo

Part-funded by the Society for Endocrinology Early Career Research Grant (

Part-funded by the Society for Endocrinology


Research interests:

Joint disorders, bone and cartilage biology, in vivo models, mouse, quail, thyroid hormone

Selected Publications

Journal Articles

Bassett J, Williams GR, 2021, Accelerating functional gene discovery in osteoarthritis, Nature Communications, Vol:12, ISSN:2041-1723, Pages:1-18

Butterfield NC, Logan JG, Waung J, et al., 2019, Quantitative X-Ray Imaging of Mouse Bone by Faxitron., Methods Mol Biol, Vol:1914, Pages:559-569

Butterfield NC, Qian C, Logan MPO, 2017, Pitx1 determines characteristic hindlimb morphologies in cartilage micromass culture, PLOS One, Vol:12, ISSN:1932-6203

Ashe A, Butterfield NC, Town L, et al., 2012, Mutations in mouse <i>Ift144</i> model the craniofacial, limb and rib defects in skeletal ciliopathies, Human Molecular Genetics, Vol:21, ISSN:0964-6906, Pages:1808-1823

Bruce SJ, Butterfield NC, Metzis V, et al., 2010, Inactivation of <i>Patched1</i> in the Mouse Limb Has Novel Inhibitory Effects on the Chondrogenic Program, Journal of Biological Chemistry, Vol:285, Pages:27967-27981

Butterfield NC, McGlinn E, Wicking C, 2010, THE MOLECULAR REGULATION OF VERTEBRATE LIMB PATTERNING, Current Topics in Developmental Biology, Vol:90, ISSN:0070-2153, Pages:319-341

Butterfield NC, Metzis V, McGlinn E, et al., 2009, Patched 1 is a crucial determinant of asymmetry and digit number in the vertebrate limb, Development, Vol:136, ISSN:0950-1991, Pages:3515-3524

More Publications