Imperial College London
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Dr Tolga Bozkurt

Faculty of Natural Sciences, Department of Life Sciences

Reader in Molecular Plant-Microbe
 
 
 
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Contact

 

+44 (0)20 7594 5381o.bozkurt

 
 
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Location

 

6167Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Dagdas:2017:10.1101/102996,
author = {Dagdas, YF and Pandey, P and Sanguankiattichai, N and Tumtas, Y and Belhaj, K and Duggan, C and Segretin, ME and Kamoun, S and Bozkurt, TO},
doi = {10.1101/102996},
title = {Host autophagosomes are diverted to a plant-pathogen interface},
url = {http://dx.doi.org/10.1101/102996},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - <jats:title>Abstract</jats:title><jats:p>Filamentous plant pathogens and symbionts invade their host cells but remain enveloped by host-derived membranes. The mechanisms underlying the biogenesis and functions of these host-microbe interfaces are poorly understood. Recently, we showed that PexRD54, an effector from the Irish potato famine pathogen <jats:italic>Phytophthora infestans</jats:italic>, binds host protein ATG8CL to stimulate autophagosome formation and deplete the selective autophagy receptor Joka2 from ATG8CL complexes. Here, we show that during <jats:italic>P. infestans</jats:italic> infection, ATG8CL autophagosomes are diverted to the pathogen interface. Our findings are consistent with the view that the pathogen coopts host selective autophagy for its own benefit.</jats:p>
AU  - Dagdas,YF
AU  - Pandey,P
AU  - Sanguankiattichai,N
AU  - Tumtas,Y
AU  - Belhaj,K
AU  - Duggan,C
AU  - Segretin,ME
AU  - Kamoun,S
AU  - Bozkurt,TO
DO  - 10.1101/102996
PY  - 2017///
TI  - Host autophagosomes are diverted to a plant-pathogen interface
UR  - http://dx.doi.org/10.1101/102996
ER  -
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