Imperial College London
Alternate

Professor Oscar Ces

Faculty of Natural Sciences, Department of Chemistry

Head of Department, August von Hofmann Chair of Chemistry
 
 
 
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Contact

 

+44 (0)20 7594 3754o.ces Website

 
 
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Location

 

G04AMolecular Sciences Research HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Thomas:2017:10.1039/C7CC05423H,
author = {Thomas, JM and Friddin, MS and Ces, O and Elani, Y},
doi = {10.1039/C7CC05423H},
journal = {Chemical Communications},
pages = {12282--12285},
title = {Programming membrane permeability using integrated membrane pores and blockers as molecular regulators},
url = {http://dx.doi.org/10.1039/C7CC05423H},
volume = {53},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - We report a bottom-up synthetic biology approach to engineering vesicles with programmable permeabilities. Exploiting the concentration-dependent relationship between constitutively active pores (alpha-hemolysin) and blockers allows blockers to behave as molecular regulators for tuning permeability, enabling us to systematically modulate cargo release kinetics without changing the lipid fabric of the system.
AU  - Thomas,JM
AU  - Friddin,MS
AU  - Ces,O
AU  - Elani,Y
DO  - 10.1039/C7CC05423H
EP  - 12285
PY  - 2017///
SN  - 1359-7345
SP  - 12282
TI  - Programming membrane permeability using integrated membrane pores and blockers as molecular regulators
T2  - Chemical Communications
UR  - http://dx.doi.org/10.1039/C7CC05423H
UR  - http://hdl.handle.net/10044/1/51915
VL  - 53
ER  -
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