Imperial College London


Faculty of MedicineInstitute of Clinical Sciences

Visiting Professor



+44 (0)20 3313 4318oliver.howes Website




Steiner MRI UnitHammersmith HospitalHammersmith Campus





Oliver Howes is Group Head and Professor of Molecular Psychiatry. His clinical work is as Consultant Psychiatrist at The Institute of Psychiatry/ Maudsley Hospital.

Contact: tel: +44 (0)20 8383 3298

Mental illnesses are a major cause of ill health and premature death. They account for four of the six leading causes of adult disability in the world and one in every ten hospital beds in the UK is allocated for the treatment of psychotic disorders such as schizophrenia.

“Our research focuses on understanding the causes of mental illnesses and improving their treatment using PET and other functional imaging techniques" 

Current work in the group focuses on:

  • Understanding the brain changes that lead to the development of psychotic disorders, using multi-modal imaging with PET and MRI
  • Examining the effects of cannabis and other drugs on the brain, and the influence of common genetic polymorphisms on brain function
  • Determining why some patients respond to treatments and others don’t
  • Using novel approaches to diagnosing mental illnesses
  • Developing models for future drug development



D’Ambrosio E, Pergola G, Pardiñas AF, et al., 2022, A polygenic score indexing a DRD2-related co-expression network is associated with striatal dopamine function, Scientific Reports, Vol:12

Krajner F, Hadaya L, McQueen G, et al., 2022, Subcortical volume reduction and cortical thinning 3 months after switching to clozapine in treatment resistant schizophrenia, Schizophrenia, Vol:8

Harvey PD, Bosia M, Cavallaro R, et al., 2022, Cognitive dysfunction in schizophrenia: An expert group paper on the current state of the art, Schizophrenia Research: Cognition, Vol:29, ISSN:2215-0013

Lally J, Ajnakina O, Stubbs B, et al., 2022, Vitamin D and cardiometabolic outcomes in first episode psychosis (FEP): A prospective cohort study, Schizophrenia Research, Vol:246, ISSN:0920-9964, Pages:26-29

Griffiths K, Egerton A, Millgate E, et al., 2022, Impaired verbal memory function is related to anterior cingulate glutamate levels in schizophrenia: findings from the STRATA study., Schizophrenia (heidelb), Vol:8

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