Imperial College London
Alternate

DrOliverRatmann

Faculty of Natural Sciences, Department of Mathematics

Reader in Statistics and Machine Learning for Public Good
 
 
 
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oliver.ratmann05 Website

 
 
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525Huxley BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Bogers:2022:10.1016/j.lanepe.2022.100515,
author = {Bogers, SJ and van, der Loeff MFS and Boyd, A and Davidovich, U and van, der Valk M and Brinkman, K and Sigaloff, K and Branger, J and Bokhizzou, N and de, Bree GJ and Reiss, P and van, Bergen JEAM and Geerlings, SE},
doi = {10.1016/j.lanepe.2022.100515},
journal = {The Lancet Regional Health. Europe},
title = {Improving indicator-condition guided testing for HIV in the hospital setting (PROTEST 2.0): a multicenter, interrupted time-series analysis},
url = {http://dx.doi.org/10.1016/j.lanepe.2022.100515},
volume = {23},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BackgroundIndicator-condition (IC) guided HIV testing is a feasible and cost-effective strategy to identify undiagnosed people living with HIV (PLHIV), but remains insufficiently implemented. We aimed to promote IC-guided HIV testing in seven ICs.MethodsRelevant departments in five hospitals of the Amsterdam region participated. HIV testing among adult patients without known HIV infection but with an IC was assessed using electronic health records during pre-intervention (January 2015–June 2020) and intervention (July 2020–June 2021) periods. The multifaceted intervention included audit and feedback. The primary endpoint was HIV testing ≤3 months before or after IC diagnosis and the effect of the intervention was evaluated using segmented Poisson regression.FindingsData from 7986 patients were included, of whom 6730 (84·3%) were diagnosed with an IC in the pre-intervention period and 1256 (15·7%) in the intervention period. The proportion HIV tested ≤3 months before or after IC diagnosis increased from 36.8% to 47.0% (adjusted risk ratio [RR]= 1.16, 95% CI=1.03–1.30, p=0.02). For individual ICs, we observed significant increases in HIV testing among patients with cervical cancer or intraepithelial neoplasia grade 3 (adjusted RR=3.62, 95% CI=1.93–6.79) and peripheral neuropathy (adjusted RR=2.27 95% CI=1.48–3.49), but not the other ICs. Eighteen of 3068 tested patients were HIV positive (0.6%).InterpretationOverall IC-guided testing improved after the intervention, but not for all ICs. Variations in effect by IC may have been due to variations in implemented developments, but the effect of separate elements could not be assessed.
AU  - Bogers,SJ
AU  - van,der Loeff MFS
AU  - Boyd,A
AU  - Davidovich,U
AU  - van,der Valk M
AU  - Brinkman,K
AU  - Sigaloff,K
AU  - Branger,J
AU  - Bokhizzou,N
AU  - de,Bree GJ
AU  - Reiss,P
AU  - van,Bergen JEAM
AU  - Geerlings,SE
DO  - 10.1016/j.lanepe.2022.100515
PY  - 2022///
SN  - 2666-7762
TI  - Improving indicator-condition guided testing for HIV in the hospital setting (PROTEST 2.0): a multicenter, interrupted time-series analysis
T2  - The Lancet Regional Health. Europe
UR  - http://dx.doi.org/10.1016/j.lanepe.2022.100515
UR  - https://www.sciencedirect.com/science/article/pii/S2666776222002113
UR  - http://hdl.handle.net/10044/1/109446
VL  - 23
ER  -
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