Publications
221 results found
Ch'ng JL, Christofides ND, Anand P, et al., 1985, Distribution of galanin immunoreactivity in the central nervous system and the responses of galanin-containing neuronal pathways to injury., Neuroscience, Vol: 16, Pages: 343-354, ISSN: 0306-4522
Radioimmunoassay and immunocytochemistry were used to study the distribution of galanin, a novel 29 amino acid porcine intestinal peptide, in the central nervous system of the rat and pig. The pattern of distribution was similar in the two species, with the highest concentrations of galanin-like immunoreactivity found in the neurohypophysis, hypothalamus and sacral spinal cord. Immunocytochemical studies of these regions localized galanin-like immunoreactivity to cell bodies in the paraventricular and supraoptic nuclei of the hypothalamus, to fibres in the pars nervosa and to numerous cell bodies and fibres in the dorsal horn of the spinal cord. On both gel and high pressure liquid chromatography, galanin-like immunoreactivity in rat and pig nervous tissue eluted as a single peak in a position similar to purified procine intestinal galanin standard. Surgical and pharmacological manipulations in the rat suggest the presence of galanin in afferent fibres. An increase of galanin-like immunoreactivity was observed in the sacral spinal cord of the rat following thoracic spinal cord transection. Thus galanin-like immunoreactivity in the brain is mainly localized in the hypothalamopituitary region. The decrease of galanin-like immunoreactivity in the dorsal horn of the spinal cord, following dorsal rhizotomy and pre-treatment of rats with capsaicin, indicates that many of the fibres, which are of small diameter, may well be derived from spinal sensory neurones.
ANAND P, POLAK JM, BLOOM SR, 1985, ASPECTS OF NEURO-HORMONAL PEPTIDES, CLINICAL PHYSIOLOGY, Vol: 5, Pages: 111-120, ISSN: 0144-5979
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- Citations: 1
NAMBA M, GHATEI MA, ANAND P, et al., 1985, DISTRIBUTION AND CHROMATOGRAPHIC CHARACTERIZATION OF NEUROMEDIN B-LIKE IMMUNOREACTIVITY IN THE HUMAN SPINAL-CORD, BRAIN RESEARCH, Vol: 342, Pages: 183-186, ISSN: 0006-8993
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- Citations: 13
SUZUKI H, CHRISTOFIDES ND, ANAND P, et al., 1985, REGIONAL DISTRIBUTION OF A NOVEL PITUITARY PROTEIN-(7B2) IN THE RAT SPINAL-CORD - EFFECT OF NEONATAL CAPSAICIN TREATMENT AND THORACIC CORD TRANSECTION, NEUROSCIENCE LETTERS, Vol: 55, Pages: 151-156, ISSN: 0304-3940
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- Citations: 16
ANAND P, BLOOM SR, 1984, NEUROPEPTIDES ARE SELECTIVE MARKERS OF SPINAL-CORD AUTONOMIC PATHWAYS, TRENDS IN NEUROSCIENCES, Vol: 7, Pages: 267-268, ISSN: 0166-2236
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- Citations: 15
GIBSON SJ, POLAK JM, ANAND P, et al., 1984, THE DISTRIBUTION AND ORIGIN OF VIP IN THE SPINAL-CORD OF 6 MAMMALIAN-SPECIES, PEPTIDES, Vol: 5, Pages: 201-207, ISSN: 0196-9781
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- Citations: 75
ANAND P, GIBSON SJ, YIANGOU Y, et al., 1984, PHI-LIKE IMMUNOREACTIVITY CO-LOCATES WITH THE VIP-CONTAINING SYSTEM IN HUMAN LUMBOSACRAL SPINAL-CORD, NEUROSCIENCE LETTERS, Vol: 46, Pages: 191-196, ISSN: 0304-3940
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- Citations: 17
GIBSON SJ, ANAND P, MCGREGOR GP, et al., 1983, A RAPID DISSECTION TECHNIQUE FOR IMPROVED RECOVERY OF SUBSTANCE-P IN THE RAT SPINAL-CORD, JOURNAL OF PATHOLOGY, Vol: 140, Pages: 173-174, ISSN: 0022-3417
ANAND P, BLOOM SR, MCGREGOR GP, 1983, TOPICAL CAPSAICIN PRETREATMENT INHIBITS AXON REFLEX VASODILATATION CAUSED BY SOMATOSTATIN AND VASOACTIVE INTESTINAL POLYPEPTIDE IN HUMAN-SKIN, BRITISH JOURNAL OF PHARMACOLOGY, Vol: 78, Pages: 665-669, ISSN: 0007-1188
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- Citations: 85
ANAND P, GIBSON SJ, MCGREGOR GP, et al., 1983, A VIP-CONTAINING SYSTEM CONCENTRATED IN THE LUMBOSACRAL REGION OF HUMAN SPINAL-CORD, NATURE, Vol: 305, Pages: 143-145, ISSN: 0028-0836
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- Citations: 116
GIBSON SJ, HUANG W, ADRIAN T, et al., 1983, THE DISTRIBUTION OF A NEWLY DISCOVERED BRAIN PEPTIDE, NEUROPEPTIDE-Y, IN THE SPINAL-CORD OF THE RAT, CAT, MONKEY AND HORSE, JOURNAL OF PATHOLOGY, Vol: 140, Pages: 172-173, ISSN: 0022-3417
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