Imperial College London
Portrait Picture

ProfessorPhillipBennett

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Clinical Professor
 
 
 
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Contact

 

+44 (0)20 7594 2176p.bennett

 
 
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Assistant

 

Miss Kiran Dosanjh +44 (0)20 7594 2176

 
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Location

 

Hammersmith HospitalHammersmith Campus

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Summary

 

Publications

Publication Type
Year
to

669 results found

Slater D, Dennes W, Sawdy R, Allport V, Bennett Pet al., 1999, Expression of cyclo-oxygenase types-1 and -2 in human fetal membranes throughout pregnancy, JOURNAL OF MOLECULAR ENDOCRINOLOGY, Vol: 22, Pages: 125-130, ISSN: 0952-5041

Journal article

Dennes WJB, Slater DM, Poston L, Bennett PRet al., 1999, Myometrial nitric oxide synthase messenger ribonucleic acid expression does not change throughout gestation or with the onset of labor, AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, Vol: 180, Pages: 387-392, ISSN: 0002-9378

Journal article

Sawdy RJ, Dennes WJB, Allport V, Slater DM, Elder MG, Sullivan MHF, Bennett PRet al., 1999, Region and labour-dependent synthesis of prostaglandin E2 by human fetal membranes, PLACENTA, Vol: 20, Pages: 181-184, ISSN: 0143-4004

Journal article

Fisk NM, Howard C, Ware M, Bennett PRet al., 1999, X-chromosome inactivation patterns do not implicate asymmetric splitting of the inner cell mass in the aetiology of twin-twin transfusion syndrome, MOLECULAR HUMAN REPRODUCTION, Vol: 5, Pages: 52-56, ISSN: 1360-9947

Journal article

Brown NL, Alvi SA, Elder MG, Bennett PR, Sullivan MHFet al., 1998, Regulation of prostaglandin production in intact fetal membranes by interleukin-1 and its receptor antagonist, JOURNAL OF ENDOCRINOLOGY, Vol: 159, Pages: 519-526, ISSN: 0022-0795

Journal article

Campagnoli C, Fisk N, Bennett P, Overton T, Roberts Iet al., 1998, Circulating multipotent haemopoietic progenitors in first trimester fetal blood., BLOOD, Vol: 92, Pages: 142B-142B, ISSN: 0006-4971

Journal article

Sawdy R, Knock GA, Bennett PR, Poston L, Aaronson PIet al., 1998, Effect of nimesulide and indomethacin on contractility and the Ca<SUP>2+</SUP> channel current in myometrial smooth muscle from pregnant women, BRITISH JOURNAL OF PHARMACOLOGY, Vol: 125, Pages: 1212-1217, ISSN: 0007-1188

Journal article

Brown NL, Alvi SA, Elder MG, Bennett PR, Sullivan MHFet al., 1998, Interleukin-1β and bacterial endotoxin change the metabolism of prostaglandins E<sub>2</sub> and F<sub>2α</sub> in intact term fetal membranes, PLACENTA, Vol: 19, Pages: 625-630, ISSN: 0143-4004

Journal article

Al-Mufti R, Howard C, Overton T, Holzgreve W, Gaenshirt D, Fisk NM, Bennett Pet al., 1998, Detection of fetal messenger ribonucleic acid in maternal blood to determine fetal RhD status as a strategy for noninvasive prenatal diagnosis, AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, Vol: 179, Pages: 210-214, ISSN: 0002-9378

Journal article

Slater D, Allport V, Bennett P, 1998, Changes in the expression of the type-2 but not the type-1 cyclo-oxygenase enzyme in chorion-decidua with the onset of labour, BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol: 105, Pages: 745-748, ISSN: 0306-5456

Journal article

Brown NL, Alvi SA, Elder MG, Bennett PR, Sullivan MHFet al., 1998, A spontaneous induction of fetal membrane prostaglandin production precedes clinical labour, JOURNAL OF ENDOCRINOLOGY, Vol: 157, Pages: R1-R6, ISSN: 0022-0795

Journal article

Rajasingam D, Bennett PR, Alvi SA, Elder MG, Sullivan MHFet al., 1998, Stimulation of prostaglandin production from intact human fetal membranes by bacteria and bacterial products, PLACENTA, Vol: 19, Pages: 301-306, ISSN: 0143-4004

Journal article

Abu-Amero SN, Ali Z, Bennett P, Vaughan JI, Moore GEet al., 1998, Expression of the insulin-like growth factors and their receptors in term placentas: A comparison between normal and IUGR births, MOLECULAR REPRODUCTION AND DEVELOPMENT, Vol: 49, Pages: 229-235, ISSN: 1040-452X

Journal article

Knock G, Sawdy R, Smirnov S, Poston L, Bennett P, Aaronson Pet al., 1998, Inhibition by nimesulide of spontaneous contractions and the voltage-gated Ca<SUP>2+</SUP> current in human myometrium, JOURNAL OF PHYSIOLOGY-LONDON, Vol: 507P, Pages: 69P-70P, ISSN: 0022-3751

Journal article

Benachi A, Garritsen HSP, Howard CM, Bennett P, Fisk NMet al., 1998, Absence of expression of RhD by human trophoblast cells, AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, Vol: 178, Pages: 294-299, ISSN: 0002-9378

Journal article

Bennett P, Sawdy R, Slater D, 1998, The role of cyclooxygenase-2 in reproduction, William Harvey Research Conference, Publisher: WILLIAM HARVEY PRESS, Pages: 171-183

Conference paper

Slater DM, Sawdy R, Dennes WJB, Allport V, Bennett PRet al., 1998, Cyclooxygenase type-2 selective nonsteroidal anti-inflammatory drugs for inhibition of preterm labor, 4th International Congress on Essential Fatty Acids and Eicosanoids, Publisher: AMER OIL CHEMISTS SOC, Pages: 64-67

Conference paper

Dennes WJB, Slater DM, Bennett PR, 1997, Nitric oxide and the control of human parturition, Contemporary Reviews in Obstetrics and Gynaecology, Vol: 9, Pages: 245-251, ISSN: 0953-9182

Preterm labor remains the single biggest predictor of neonatal morbidity and mortality. The factors responsible for the onset of labor at term are not clearly defined, and the onset of preterm labor is similarly poorly understood. Since nitric oxide (NO) was first identified, there has been increasing interest in its role during pregnancy and the onset of labor. Its physiological function as a potent mediator of smooth muscle relaxation implicates a role in myometrial quiescence during pregnancy, and changes in NO levels might be one of many factors responsible for the onset of labor. This article reviews the current evidence, from both animal and human studies, of the putative roles of NO in the onset of parturition and considers the therapeutic use of NO donors in tocolysis.

Journal article

Benachi A, Garritsen HSP, Howard CM, Bennett P, Fisk NMet al., 1997, Lack of expression of Rh-D in human trophoblast, Infusionstherapie und Transfusionsmedizin, Vol: 24, ISSN: 1424-5485

OBJECTIVE: To determine whether the Rh D is expressed in trophoblast at any stage of gestation. STUDY DESIGN: Trophoblast and fetal tissue were obtained from 18 pregnancies at 8 to 40 weeks gestation. Deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) were extracted from trophoblast. cDNA was synthesised from RNA and reverse-transcriptase polymerase chain reaction was performed using primers within the Rh D gene. DNA was extracted from fetal tissue to determine, using polymerase chain reaction (PCR), the fetal Rh D status. PCR products were resolved by agarose gel electrophoresis. Antigen expression was also sought by analytical cytometric analysis (flowcytometry and immunohistochemistry) using a monoclonal anti D antibody. RESULTS: We studied trophoblast from various combinations of Rh D and Rh d fetuses (on DNA) from Rh D and Rh d mothers to find no Rh D gene expression in any sample. FACS and immunocytochemistry data confirmed this by demonstrating no Rh D antigen sites on trophoblast cells. CONCLUSION: Contrary to a previous report, we conclude that the Rh D gene is not expressed in human trophoblast in any trimester.

Journal article

Bennett P, Edwards D, 1997, Use of magnesium sulphate in obstetrics, LANCET, Vol: 350, Pages: 1491-1491, ISSN: 0140-6736

Journal article

Benachi A, Garritsen HSP, Howard CM, Bennett P, Fisk MMet al., 1997, Lack of expression of Rh-D in human trophoblast., Publisher: AMER ASSOC BLOOD BANKS, Pages: S398-S398, ISSN: 0041-1132

Conference paper

Sawdy R, Slater D, Fisk N, Edmonds DK, Bennett Pet al., 1997, Use of a cyclo-oxydenase type-2-selective non-steroidal anti-inflammatory agent to prevent preterm delivery, LANCET, Vol: 350, Pages: 265-266, ISSN: 0140-6736

Journal article

Dennes WJB, Slater DM, Bennett PR, 1997, Nitric oxide synthase mRNA expression in human fetal membranes: A possible role in parturition, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Vol: 233, Pages: 276-278, ISSN: 0006-291X

Journal article

Moore GE, Ali Z, Khan RU, Blunt S, Bennett PR, Vaughan JIet al., 1997, The incidence of uniparental disomy associated with intrauterine growth retardation in a cohort of thirty-five severely affected babies, AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, Vol: 176, Pages: 294-299, ISSN: 0002-9378

Journal article

ORiordan S, Greenough A, Moore GE, Bennett P, Nicolaides KHet al., 1996, Case report: Uniparental disomy 16 in association with congenital heart disease, PRENATAL DIAGNOSIS, Vol: 16, Pages: 963-965, ISSN: 0197-3851

Journal article

Overton TG, Lighten AD, Fisk NM, Bennett PRet al., 1996, Prenatal Diagnosis by minimally invasive first-trimester transcervical sampling is unreliable, AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, Vol: 175, Pages: 382-387, ISSN: 0002-9378

Journal article

Overton TG, Lighten AD, Fisk NM, Bennett PRet al., 1996, Prenatal diagnosis by minimally invasive first trimester sampling is unreliable., BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol: 103, Pages: 846-846, ISSN: 0306-5456

Journal article

Fisk NH, Ware M, Stanier P, Moore G, Bennett Pet al., 1996, Molecular genetic etiology of twin reversed arterial perfusion sequence, AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, Vol: 174, Pages: 891-894, ISSN: 0002-9378

Journal article

Xue S, Slater DM, Bennett PR, Myatt Let al., 1996, Induction of both cytosolic phospholipase A(2) and prostaglandin H synthase-2 by interleukin-1 beta in WISH cells is inhibited by dexamethasone, PROSTAGLANDINS, Vol: 51, Pages: 107-124, ISSN: 0090-6980

Journal article

LIGHTEN AD, OVERTON TG, SEPULVEDA W, WARWICK RM, FISK NM, BENNETT PRet al., 1995, ACCURACY OF PRENATAL DETERMINATION OF RHD TYPE STATUS BY POLYMERASE CHAIN-REACTION WITH AMNIOTIC CELLS, AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, Vol: 173, Pages: 1182-1185, ISSN: 0002-9378

Journal article

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