Imperial College London
Alternate

Professor Peter GJ Burney MA MD FRCP FFPHM FMedSci

Faculty of Medicine, National Heart & Lung Institute

Emeritus Professor of Respiratory Epidemiology
 
 
 
//

Contact

 

+44 (0)20 7594 7941p.burney

 
 
//

Location

 

07Emmanuel Kaye BuildingRoyal Brompton Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Lyons:2019:10.1016/j.jaip.2019.02.044,
author = {Lyons, SA and Burney, PGJ and Ballmer-Weber, BK and Fernandez-Rivas, M and Barreales, L and Clausen, M and Dubakiene, R and Fernandez-Perez, C and Fritsche, P and Jedrzejczak-Czechowicz, M and Kowalski, ML and Kralimarkova, T and Kummeling, I and Mustakov, TB and Lebens, AFM and van, Os-Medendorp H and Papadopoulos, NG and Popov, TA and Sakellariou, A and Welsing, PMJ and Potts, J and Mills, ENC and van, Ree R and Knulst, AC and Le, T-M},
doi = {10.1016/j.jaip.2019.02.044},
journal = {Journal of Allergy and Clinical Immunology: In Practice},
pages = {1920--1928.e11},
title = {Food allergy in adults: substantial variation in prevalence and causative foods across Europe},
url = {http://dx.doi.org/10.1016/j.jaip.2019.02.044},
volume = {7},
year = {2019}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BACKGROUND: The EuroPrevall study showed that prevalence of self-reported food allergy (FA) in adults across Europe ranged from 2-37% for any food and 1-19% for 24 selected foods. OBJECTIVE: To determine prevalence of probable FA (symptoms plus sIgE-sensitisation) and challenge-confirmed FA in European adults, along with symptoms and causative foods. METHODS: In phase I of the EuroPrevall project, a screening questionnaire was sent to a random sample of the general adult population in eight European centres. Phase II consisted of an extensive questionnaire on reactions to 24 pre-selected commonly implicated foods, and measurement of sIgE. Multiple imputation was performed performed to estimate missing symptom and serology information for non-responders. In the final phase, subjects with probable FA were invited for double-blind placebo-controlled food challenge. RESULTS: Prevalence of probable FA in adults in Athens, Reykjavik, Utrecht, Lodz, Madrid and Zurich was respectively 0.3%, 1.4%, 2.1%, 2.8%, 3.3% and 5.6%. Oral allergy symptoms were reported most frequently (81.6%), followed by skin symptoms (38.2%) and rhino-conjunctivitis (29.5%). Hazelnut, peach and apple were the most common causative foods in Lodz, Utrecht and Zurich. Peach was also among the top three causative foods in Athens and Madrid. Shrimp and fish allergies were relatively common in Madrid and Reykjavik. Of the 55 food challenges performed, 72.8% was classified as positive. CONCLUSION: Food allergy shows substantial geographical variation in prevalence and causative foods across Europe. Although probable FA is less common than self-reported FA, prevalence still reaches 6% in parts of Europe.
AU  - Lyons,SA
AU  - Burney,PGJ
AU  - Ballmer-Weber,BK
AU  - Fernandez-Rivas,M
AU  - Barreales,L
AU  - Clausen,M
AU  - Dubakiene,R
AU  - Fernandez-Perez,C
AU  - Fritsche,P
AU  - Jedrzejczak-Czechowicz,M
AU  - Kowalski,ML
AU  - Kralimarkova,T
AU  - Kummeling,I
AU  - Mustakov,TB
AU  - Lebens,AFM
AU  - van,Os-Medendorp H
AU  - Papadopoulos,NG
AU  - Popov,TA
AU  - Sakellariou,A
AU  - Welsing,PMJ
AU  - Potts,J
AU  - Mills,ENC
AU  - van,Ree R
AU  - Knulst,AC
AU  - Le,T-M
DO  - 10.1016/j.jaip.2019.02.044
EP  - 1928
PY  - 2019///
SN  - 2213-2198
SP  - 1920
TI  - Food allergy in adults: substantial variation in prevalence and causative foods across Europe
T2  - Journal of Allergy and Clinical Immunology: In Practice
UR  - http://dx.doi.org/10.1016/j.jaip.2019.02.044
UR  - https://www.ncbi.nlm.nih.gov/pubmed/30898689
UR  - http://hdl.handle.net/10044/1/68696
VL  - 7
ER  -
Download