Imperial College London
Alternate

ProfessorPeterEllaway

Faculty of Medicine, Department of Brain Sciences

Emeritus Professor of Physiology
 
 
 
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Contact

 

+44 (0)20 8398 6639p.ellaway

 
 
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Location

 

Lab BlockCharing Cross Campus

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Summary

 

Publications

Publication Type
Year
to

185 results found

Ellaway PH, Davey NJ, Ljubisavljevic MJ, Anissimova NPet al., 1995, Regulation of the dynamic and static sensitivity of gastrocnemius-soleus muscle spindle afferents by joint and cutaneous afferents in the cat, Symposium on Alpha and Gamma Motor Systems, Publisher: PLENUM PRESS DIV PLENUM PUBLISHING CORP, Pages: 151-156

Conference paper

ELLAWAY PH, 1995, FUSIMOTOR REFLEXES FROM JOINT AND CUTANEOUS AFFERENTS, 32nd Congress of the International-Union-of-Physiological-Sciences, Publisher: PLENUM PRESS DIV PLENUM PUBLISHING CORP, Pages: 89-96

Conference paper

Davey NJ, Ellaway PH, Maskill DW, Anissimova NPet al., 1995, The basis of variability in magnitude of the response of muscles to transcranial magnetic stimulation of the motor cortex in man, Symposium on Alpha and Gamma Motor Systems, Publisher: PLENUM PRESS DIV PLENUM PUBLISHING CORP, Pages: 387-389

Conference paper

ELLAWAY PH, DAVEY NJ, LUBJSAVLIJEVIC M, ANISSIMOVA NPet al., 1994, TONIC SUPRASPINAL REGULATION OF THE ACTION OF JOINT AND CUTANEOUS AFFERENTS ON THE DYNAMIC AND STATIC SENSITIVITY OF SPINDLE AFFERENTS IN THE CAT, JOURNAL OF PHYSIOLOGY-LONDON, Vol: 479P, Pages: P30-P30, ISSN: 0022-3751

Journal article

Davey NJ, Romaiguère P, Maskill DW, Ellaway PHet al., 1994, Suppression of voluntary motor activity revealed using transcranial magnetic stimulation of the motor cortex in man., J Physiol, Vol: 477, Pages: 223-235, ISSN: 0022-3751

1. Suppression of voluntary muscle activity of hand and arm muscles in response to transcranial magnetic stimulation (TMS) of the motor cortex has been investigated in man. 2. Suppression could be elicited by low levels of TMS without any prior excitatory response. The latency of the suppression was 3-8 ms longer than the excitation observed at a higher stimulus intensity. The duration of the suppression ranged from 8 to 26 ms. 3. A circular stimulating coil was used to determine threshold intensity for excitation and suppression of contraction of thenar muscles in response to TMS at different locations over the motor cortex. The locations for lowest threshold excitation coincided with those for lowest threshold suppression. Suppression was elicited at a lower threshold than excitation at all locations. 4. A figure-of-eight stimulating coil was positioned over the left motor cortex at the lowest threshold point for excitation of the right thenar muscles. The orientation for the lowest threshold excitatory and inhibitory responses was the same for all subjects. That orientation induced a stimulating current travelling in an antero-medial direction. Suppression was invariably elicited at lower thresholds than excitation. 5. When antagonistic muscles (second and third dorsal interosseus) were co-contracted, TMS evoked coincident suppression of voluntary EMG in the two muscles without prior excitation of either muscle. This suggests that the suppression is not mediated via corticospinal activation of spinal interneurones. 6. Test responses to electrical stimulation of the cervical spinal cord were evoked in both relaxed and activated thenar muscles. In the relaxed muscle, prior TMS at an intensity that would suppress voluntary activity failed to influence the test responses, suggesting absence of inhibition at a spinal level. However, in the activated muscle, prior TMS could reduce the test response. This may be explained by disfacilitation of motoneurones due to inhibi

Journal article

DAVEY NJ, ROMAIGUERE P, MASKILL DW, ELLAWAY PHet al., 1994, SUPPRESSION OF VOLUNTARY MOTOR-ACTIVITY REVEALED USING TRANSCRANIAL MAGNETIC STIMULATION OF THE MOTOR CORTEX IN MAN, JOURNAL OF PHYSIOLOGY-LONDON, Vol: 477, Pages: 223-235, ISSN: 0022-3751

Journal article

DAVEY NJ, ELLAWAY PH, MASKILL DW, ANISSIMOVA NP, RAWLINSON SR, THOMAS HSet al., 1994, VARIABILITY IN THE AMPLITUDE OF SKELETAL-MUSCLE RESPONSES TO BILATERAL TRANSCRANIAL MAGNETIC STIMULATION IN MAN, JOURNAL OF PHYSIOLOGY-LONDON, Vol: 476P, Pages: P33-P33, ISSN: 0022-3751

Journal article

ELLAWAY PH, DAVEY NJ, MASKILL DW, 1994, INHIBITION OF MOTOR UNIT DISCHARGE IN HUMANS EVOKED BY TRANSCRANIAL STIMULATION (VOL 56, PG 834, 1993), JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol: 57, Pages: 126-126, ISSN: 0022-3050

Journal article

DAVEY NJ, ELLAWAY PH, BAKER JR, FRIEDLAND CLet al., 1993, RHYTHMICITY ASSOCIATED WITH A HIGH-DEGREE OF SHORT-TERM SYNCHRONY OF MOTOR UNIT DISCHARGE IN MAN, EXPERIMENTAL PHYSIOLOGY, Vol: 78, Pages: 649-661, ISSN: 0958-0670

Journal article

ELLAWAY PH, DAVEY NJ, MASKILL DW, 1993, INHIBITION OF MOTOR UNIT DISCHARGE IN HUMANS EVOKED BY TRANSCRANIAL STIMULATION, JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol: 56, Pages: 833-834, ISSN: 0022-3050

Journal article

DAVEY NJ, MURPHY K, MASKILL DW, GUZ A, ELLAWAY PHet al., 1993, EVIDENCE CONCERNING THE SITE OF FACILITATION OF PHRENIC MOTONEURON OUTPUT IN RESPONSE TO VOLITIONAL INSPIRATION IN MAN, JOURNAL OF PHYSIOLOGY-LONDON, Vol: 473, Pages: P61-P61, ISSN: 0022-3751

Journal article

POPE AJ, REDMAN AGO, LEWIS MM, DAVEY NJ, ELLAWAY PHet al., 1993, THE EFFECT OF WRIST ANGLE ON THE RESPONSE OF A WRIST EXTENSOR MUSCLE TO TRANSCRANIAL MAGNETIC STIMULATION IN MAN, JOURNAL OF PHYSIOLOGY-LONDON, Vol: 459, Pages: P470-P470, ISSN: 0022-3751

Journal article

DAVEY NJ, ROMAIGUERE P, MASKILL DW, ELLAWAY PHet al., 1993, IS THE INHIBITION OF VOLUNTARY CONTRACTION EVOKED BY TRANSCRANIAL MAGNETIC STIMULATION IN MAN OCCURRING AT THE LEVEL OF THE CEREBRAL-CORTEX, JOURNAL OF PHYSIOLOGY-LONDON, Vol: 459, Pages: P150-P150, ISSN: 0022-3751

Journal article

DAVEY NJ, ROMAIGUERE P, MASKILL DW, ELLAWAY PHet al., 1993, MAPPING OF MOTOR INHIBITION EVOKED BY TRANSCRANIAL MAGNETIC STIMULATION DURING VOLUNTARY CONTRACTION IN MAN, JOURNAL OF PHYSIOLOGY-LONDON, Vol: 459, Pages: P66-P66, ISSN: 0022-3751

Journal article

WELLS E, ROMAIGUERE P, ELLAWAY PH, 1993, MOTOR UNIT TWITCH CONTRACTION TIMES ARE SIMILAR IN NORMAL SUBJECTS AND IN MOTOR-NEURON DISEASE, JOURNAL OF PHYSIOLOGY-LONDON, Vol: 459, Pages: P71-P71, ISSN: 0022-3751

Journal article

BAKER JR, DAVEY NJ, ELLAWAY PH, FRIEDLAND CLet al., 1992, SHORT-TERM SYNCHRONY OF MOTOR UNIT DISCHARGE DURING WEAK ISOMETRIC CONTRACTION IN PARKINSONS-DISEASE, BRAIN, Vol: 115, Pages: 137-154, ISSN: 0006-8950

Journal article

Baker JR, Davey NJ, Ellaway PH, Friedland CLet al., 1992, Short-term synchrony of motor unit discharge during weak isometric contraction in Parkinson's disease., Brain, Vol: 115 Pt 1, Pages: 137-154, ISSN: 0006-8950

Short-term synchrony between the discharges of motor units has been assessed in Parkinson's disease (PD) and normal man. The discharges of single motor units were recorded in the extensor digitorum communis (EDC) muscle of the forearm or the tibialis anterior (TA) muscle of the leg during weak, voluntary isometric contraction. Short-term synchrony was defined as a narrow peak (total width less than 25 ms) in cross-correlograms constructed from the discharges of pairs of motor units. There was no difference in the incidence of short-term synchrony between PD and normal age-matched subjects for either the EDC or TA muscle. On average, 60% of pairs of motor units exhibited synchrony, but this varied between 0% and 100% for both groups. The amount of short-term synchrony was assessed as the probability (above chance) of discharge of one motor unit with respect to the other. In TA, but not EDC, this index was greater for PD than for normal subjects. The high indices of synchrony in TA in PD were not related to lower discharge rates of motor units. Parkinson's disease subjects, but not normal subjects, also showed broad correlations that were invariably associated with periodic discharges in the range 4-6 Hz. In some instances, a peak of short-term synchrony was observed superimposed on the broad correlation. The periodic correlograms were often associated with overt tremor which accompanied the contraction. Motor units occasionally discharged paired impulses (doublet discharges) with short interspike intervals of 5-15 ms (normal and PD) or, as a more persistent feature in PD, longer interspike doublets (20-60 ms) associated with periodic synchrony (4-6 Hz). The abnormal discharge characteristics of motor units are discussed in relation to the bulbospinal control of presynaptic drive to motor neurons in PD.

Journal article

BAXENDALE RH, DAVEY NJ, ELLAWAY PH, FERRELL WRet al., 1992, THE INTERACTION BETWEEN JOINT AND CUTANEOUS AFFERENT INPUT IN THE REGULATION OF FUSIMOTOR NEURON DISCHARGE, IBRO SYMP ON MUSCLE AFFERENTS AND SPINAL CONTROL OF MOVEMENT, TO HONOUR PROFESSOR YVES LAPORTE, Publisher: PERGAMON PRESS LTD, Pages: 95-104

Conference paper

DAVEY NJ, ROMAIGUERE P, MASKILL DW, ELLAWAY PHet al., 1992, INHIBITION OF VOLUNTARY CONTRACTION BY TRANSCRANIAL MAGNETIC STIMULATION OF THE BRAIN SUBTHRESHOLD FOR EXCITATION IN MAN, JOURNAL OF PHYSIOLOGY-LONDON, Vol: 446, Pages: P447-P447, ISSN: 0022-3751

Journal article

ELLAWAY PH, HAGUE HR, HARRISON F, TANSEY EMet al., 1991, JANUARY 1891 - THE PHYSIOLOGICAL-SOCIETY AT CHARING CROSS, JOURNAL OF PHYSIOLOGY-LONDON, Vol: 438, Pages: P6-P6, ISSN: 0022-3751

Journal article

BAKER JR, DAVEY NJ, ELLAWAY PH, FRIEDLAND CLet al., 1991, DELAYED MOTOR UNIT DISCHARGES ASSOCIATED WITH A HIGH DEGREE OF SHORT-TERM SYNCHRONY IN ISOMETRIC CONTRACTIONS IN MAN, JOURNAL OF PHYSIOLOGY-LONDON, Vol: 438, Pages: P40-P40, ISSN: 0022-3751

Journal article

DAVEY NJ, DICK JPR, ELLAWAY PH, MASKILL DWet al., 1991, RAISED MOTOR CORTICAL THRESHOLD ASSOCIATED WITH BRADYKINESIA AS REVEALED BY TRANSCRANIAL MAGNETIC STIMULATION IN NORMAL MAN AND PARKINSONS-DISEASE, JOURNAL OF PHYSIOLOGY-LONDON, Vol: 438, Pages: P35-P35, ISSN: 0022-3751

Journal article

DAVEY NJ, ELLAWAY PH, MASKILL DW, 1991, FACILITATION BY MECHANICAL CUTANEOUS STIMULATION OF MUSCLE RESPONSES TO TRANSCRANIAL MAGNETIC STIMULATION IN MAN, JOURNAL OF PHYSIOLOGY-LONDON, Vol: 438, Pages: P7-P7, ISSN: 0022-3751

Journal article

BAKER JR, CATLEY MC, DAVEY NJ, ELLAWAY PHet al., 1991, INFLUENCE OF THE PONTINE AND MEDULLARY RETICULAR-FORMATION ON SYNCHRONY OF GAMMA MOTONEURON DISCHARGE IN THE CAT, EXPERIMENTAL BRAIN RESEARCH, Vol: 87, Pages: 604-614, ISSN: 0014-4819

Journal article

ELLAWAY PH, GARTSIDE IB, ROMAIGUERE P, RAWLINSON SR, WELLS Eet al., 1991, METHOD FOR MEASURING THE TIME COURSE OF TWITCH TENSION FROM A SINGLE MOTOR UNIT IN MAN, JOURNAL OF PHYSIOLOGY-LONDON, Vol: 438, Pages: P8-P8, ISSN: 0022-3751

Journal article

DAVEY NJ, ELLAWAY PH, HALLIDAY DM, ROSENBERG JRet al., 1990, ASSOCIATION BETWEEN THE DISCHARGES OF GAMMA-MOTONEURONS DURING CUTANEOUS STIMULATION REVEALED BY COHERENCE ANALYSIS IN THE CAT, JOURNAL OF PHYSIOLOGY-LONDON, Vol: 429, Pages: P35-P35, ISSN: 0022-3751

Journal article

BAXENDALE RH, DAVEY NJ, ELLAWAY PH, FERRELL WRet al., 1990, THE INFLUENCE OF CUTANEOUS RECEPTORS ON THE REFLEX PATHWAYS FROM KNEE-JOINT AFFERENTS TO GAMMA-MOTONEURONS IN THE DECEREBRATED, LOW-SPINAL CAT, JOURNAL OF PHYSIOLOGY-LONDON, Vol: 429, Pages: P34-P34, ISSN: 0022-3751

Journal article

DAVEY NJ, ELLAWAY PH, FRIEDLAND CL, SHORT DJet al., 1990, MOTOR UNIT DISCHARGE CHARACTERISTICS AND SHORT-TERM SYNCHRONY IN PARAPLEGIC HUMANS, JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol: 53, Pages: 764-769, ISSN: 0022-3050

Journal article

ELLAWAY PH, DAVEY NJ, CATLEY MC, BAKER JRet al., 1990, ORIGIN OF A BULBOSPINAL PATHWAY THAT SUPPRESSES SYNCHRONY OF GAMMA-MOTONEURON DISCHARGE IN THE DECEREBRATED CAT, JOURNAL OF PHYSIOLOGY-LONDON, Vol: 425, Pages: P81-P81, ISSN: 0022-3751

Journal article

ELLAWAY PH, 1990, IDENTIFYING TRENDS, NATURE, Vol: 344, Pages: 698-698, ISSN: 0028-0836

Journal article

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