Imperial College London

ProfessorPaulElliott

Faculty of MedicineSchool of Public Health

Chair in Epidemiology and Public Health Medicine
 
 
 
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Contact

 

+44 (0)20 7594 3328p.elliott Website

 
 
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Assistant

 

Miss Jennifer Wells +44 (0)20 7594 3328

 
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Location

 

154Norfolk PlaceSt Mary's Campus

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Summary

 

Summary

Professor Paul Elliott, MBBS, PhD, FMedSci, trained in clinical medicine and epidemiology as a Wellcome Trust Clinical Fellow at St Mary's Hospital London and the London School of Hygiene & Tropical Medicine. He studied for his PhD in Epidemiology on the INTERSALT Study under the mentorship of Professor Geoffrey Rose. He remained at the London School working as a lecturer, and subsequently as senior lecturer and reader in epidemiology before being appointed as Head of the Environmental Epidemiology Unit at LSHTM 1990. In 1995 he was appointed to the Chair in Epidemiology and Public Health Medicine at Imperial College London. Since then he has managed the transformation of the Department of Public Health into the present Department of Epidemiology and Biostatistics in the School of Public Health. The Department has expanded significantly during recent years to encompass a wide-ranging programme of health research and extensive collaborations with national and international research groups and hosting both honorary and visiting staff. Paul Elliott is also Director of the MRC-PHE Centre for Environment and Health, which was launched in 2009 as a joint collaboration with King's College London and forms a major part of the Department and includes the Small Area Health Statistics Unit (SAHSU). He is also an honorary consultant in public health medicine in the Directorate of Primary Care and Public Health of the Imperial College Healthcare NHS Trust and the academic lead for the Informatics & Biobanking research theme of the Imperial NIHR Biomedical Research Centre. He is the current Director of Information Governance for the Imperial College Academic Health Sciences Centre.

Leadership roles :
Head of Department of Epidemiology and Biostatistics
Director of MRC-PHE Centre for Environment and Health
Director of Small Area Health Statistics Unit (SAHSU)
Co-Director of MRC-NIHR National Phenome Centre
Deputy Director of HPRU on the Health Impact of Environmental Hazards
Emeritus NIHR Senior Investigator
Visiting Professor Nanyang Technological University Lee Kong Chian School of Medicine (since 2016)
ACCEA platinum award holder (original award 2008)
ISI Highly cited researcher in genomics 2014&2015
H-index 94

Key Research Interests:
Environmental epidemiology and small area health statistics
Genetic and molecular epidemiology, gene-environment interactions
Nutritional epidemiology - focus on diet, high blood pressure and cardiovascular disease
Population cohort studies and biobankiing
Non-ionising radiation and health

Key Research projects:

  • The MRC-PHE Centre for Environment and Health was created in 2009 and has established a centre for excellence in research and postgraduate training in the field of environment and health. Research themes include Exposome and Health; Air Pollution, Noise and Health; Small Area Health Studies of Environment and Health. The Centre hosts postgraduate students and fellows funded by its PhD studentship and early career fellowship schemes. Outputs of the research are fed into national and international environmental health policy through the Centre’s Risk  Assessment and Policy Evaluation research translation programme.
    MRC-PHE Centre for Environment and Health
    The Centre includes the Small Area Health Statistics Unit (SAHSU), which has expertise to assess the risk to the health of the population from environmental factors by using routinely collected health and population data at a small-area scale. Small Area Health Statistics Unit
  • AIRWAVE health monitoring study - occupational cohort study of long-term health in relation to the use of the TETRA communication system by police force personnel. Funding: Home Office, 2003-2018. The baseline survey took place between 2004-2015, with extensive data collection by a computerised questionnaire, a range of physical measurements, and collection of a 50ml non-fasting blood sample. A programme of follow-up health-screens is currently open to participants at selected locations across the country. The MRC is funding follow-up in Scotland and Wales commencing in autumn 2018. Airwave is now part of the national DPUK initiative.
    Airwave study
  • UK COSMOS - International cohort study of mobile phones and health with data on >100,000 UK mobile phone users, part of a major long-term cohort study with approx. 300,000 participants taking part across Europe - recruited in Denmark, Sweden & Finland. Baseline data collection was in 2010-2012. In 2017 the first phase of follow-up was carried out with collection of data on participant health, mobile phone use and lifestyle. Funding: Department of Health.
    UK COSMOS
  •  SCAMP Study - cohort study which which is following several thousand secondary school pupils in 39 schools across London from year 7 through to year 9. The aim of this study is to investigate whether children’s use of mobile phones and/or other technologies that use radio waves e.g. portable landline phones and wireless internet, affects their cognitive and behavioural development. The first round of follow-up data collection ended in July 2018.
    SCAMP study 
  •  AIRLESS study - NERC-funded project on the Effects of air pollution on cardiopulmonary disease in urban and peri-urban residents in Beijing. Project led by Prof Frank Kelly (King's College London).  
    AIRLESS
  •  UKDRI Imperial College Dementia Research Institute Foundation Award. Director Prof Paul Matthews. Funding from the MRC Alzheimer's Society and Alzheimer's Research UK. The new Centre is being set up with the primary aim of bringing novel approaches and research tools to the study of dementia to discover new disease mechanisms and therapeutic targets. Lead for programme on linking genetic, epidemiology and metabolic phenotyping in dementia in the context of aging, environment and lifestyle.
    Imperial College Dementia Research Institute
  • NIHR Health Protection Research Unit on Health Impacts of Environmental Hazards. Director Prof Frank Kelly, King's College London. The Unit is investigating the impact of exposure to exogenous environmental chemicals and other pollutants, to gain improved understanding of the mechanism of their interaction with human systems in order to generate new knowledge on health risks to the human population.  PI for Theme 2 Modes of Toxicity -Biochemical pathways from toxin to disease.
    NIHR HPRU Health Impacts of Environmental Hazards
  •  INTERMAP international Collaborative study of dietary macro-and micro-nutrients and blood pressure  and health. Blood pressure, dietary and urinary, anthropometric and questionnaire data were collected from 4680 men and women (40-59 years of age) recruited from 17 populations across 4 countries (Japan, China, U.K., U.S.A.) during 1997-1999. The INTERMAP data resource is currently being analysed for U.S. National Institutes of Health funded projects on: 1) Metabolomics measured urinary metabolites, diet and blood pressure and 2) Metabolic pathways underlying the contrasting sodium-blood pressure and DASH-OmniHeart-blood pressure relationships.
    INTERMAP study
  • U.S. National Institutes of Health funded project on Metabolomic signatures of coronary artery disease (CAD) associated genotypes in collaboration with Dr David Herrington (PI at Wake Forest University) and colleagues.
  • HELIOS study - epidemiological cohort study to better predict and prevent the development of chronic conditions in the Singapore population. PI Professor John Chambers (at NTU). A collaboration with Nanyang Technological University- Lee Kong Chian School of Medicine, and the National Healthcare Group Singapore.
  •  UK Biobank - PI of the UK Biobank Cardiometabolic Consortium and co-lead (with Prof Mark Caulfield) of the UK CMC blood pressure working group.


    Resource Development
  • Imperial National Phenome Centre - a national facility that provides world-leading capacity in large-scale metabolic phenotyping for academic researchers and advanced training in metabolic phenotyping technologies. Funded by MRC and NIHR. Role: Co-Director.
    Imperial National Phenome Centre
  •  UK MED-BIO Medical Bioinformatics partnership: aggregation, integration, visualisation and analysis of large, complex data. MRC-funded initiative to build high performance computing and IT resource to support the integration, processing and storage of large scale biomedical ("big") data. Role: PI.
    UK MED-BIO
  • Imperial College London Biomedical Research Centre Informatics & Biobanking research theme. The theme aims to provide world-leading health analytics and patient, tissue and population resources, linked to deep phenotypic information, omics and clinical outcomes, forming the basis for recruitment into experimental medicine studies, prognostic research and biomarker discovery, validation and qualification across the BRC.
    Through the NIHR Health Informatics Collaboration (NHIC) there is a move towards using routinely-collected electronic clinical data to provide insights into diseases and their clinical management. Role: BRC theme lead.

    NIHR Imperial College Biomedical Research Centre
  • EU HORIZON 2020 PhenoMeNal project is developing a comprehensive and standardised e-infrastructure that supports the data processing and analysis pipelines for molecular phenotype data generated by metabolomics applications.
    PhenoMeNal
  • Health Data Research UK (HDR-UK) London substantive site. Director: Professor Harry Hemingway (UCL). Part of an exciting new national initiative to develop novel, trans-disciplinary approaches to advance data science and develop scientific and computational capacity to answer important population health questions. Major themes on Actionable Analytics, Precision Medicine, Clinical Trials and Public Health. Role: associate director and co-investigator on the precision medicine theme.
    HDR-UK London
  •   UK Biobank. Roles: Founding member of the Steering Committee of UK Biobank and Chair of the Enhancements Working Group.
    UK Biobank

Research collaboration

AIRLESS - Prof Rod Jones (Cambridge), Prof Tong Zhu (Peking University), Prof Junfeng Zhang (Duke University), Prof Meiping Zhao and Yangfeng Wu (Peking University)

AIRWAVE - Prof Kate Hunt and Dr Evangelia Demou (University of Glasgow), Prof M van Tongeren (University of Manchester), Prof A McIntosh (University of Edinburgh), Prof R Lyons (Swansea University)

COMBI-BIO - D Herrington (Wake Forest University), P Greenland (Northwestern University), R Tracy (University of Vermont), E Evangelou (Ioannina University), C Gieger (Helmholtz Munich), A Deghan (Erasmus)

DPUK - Prof J Gallacher

International Consortium on Blood Pressure (ICBP) consortium M Caulfield, P Munroe, Helen Warren, Michael Barnes (QMUL), L Wain (Leicester University)

INTERMAP International collaborative study of dietary macro-and micro-nutrients and blood pressure. J Stamler, A Dyer, L van Horn (Northwestern University), M Daviglus (University of Illinois), J Molitor (University of Oregon), J Nicholson, E Holmes (Imperial College London)

LOLIPOP (London Life Sciences Prospective Population Cohort) Study - PI: J Kooner (Imperial College London) and J Chambers (NTU Singapore). http://www.lolipopstudy.org/

Northern Finland Birth Cohorts - PI: Prof M-R Jarvelin

MRC-PHE Centre for Environment and Health - Prof Frank Kelly (King's College London)

UK MED-BIO - J Griffin (MRC Cambridge), R Lyons (CIPHER Swansea)

Teaching and Supervision:

Joint course coordinator for new Masters in Health Data Analytics and Machine Learning (led by Dr Marc Chadeau-Hyam) - first student intake autumn 2018 
MSc in Health Data Analytics and Machine Learning

Contributor to new online Global Masters in Public Health commencing autumn 2019 Global Masters in Public Health

Recent lectures contributed to these courses and modules at Imperial:

Module lectures for:

BSc in Global Health
MBBS Epidemiology in Practice
MSc in Epidemiology Principles of Global Epidemiology module and Social Epidemiology module and Disease Masterclass
Masters in Public Health
Masters in Preventive Cardiology: Nutrition and Weight Management module
MReS in Clinical Research: Human Nutrition module
Masters in Health Data Analytics and Machine Learning

Short courses including : International Nutritional Epidemiology (course director: Prof Elio Riboli); Global Health (course director Dr Daniela Fecht); Stat XP (course director Dr Marc Chadeau-Hyam).

Postgraduate PhD Student Supervision:

Goncalo de Santos Correia Novel computational and chemometric methods for modelling cardiovascular metabolic phenotypic data. Joint supervisors: Prof Elaine Holmes, Paul Elliott

Robbie Parks Forecasting seasonal mortality and estimating the effect of various climate change scenarios ISSF funded studentship. Joint supervision: Prof Majid Ezzati, Ralph Toumi, Paul Elliott.

Javiera Farrido Unified approaches to cross-omic profiling. Joint supervision: Dr Marc Chadeau, Paul Elliott.

Elzbieta Lauzikaite Development and application of novel analytical methods for metabolite structure elucidation. Joint supervision: Dr Toby Athersuch, Dr Isabel Garcia-Perez , Paul Elliott, Ioanna Tzoulaki

Arinbjorn Kolbeinsson Using deep learning to predict health outcomes based on MR imaging and other high dimensional data Joint supervision: Dr Ioanna Tzoulaki, Dr Korbinian Strimmer, Paul Elliott

Jennifer Griffin Joint supervision: Prof Gary Frost.

Anwar Al Baloul Joint supervision: Prof Gary Frost

Post-doctoral fellows under supervision:

Antonio Berlanga-Taylor, PhD MRC Intermediate Research Fellowship in Computational Biology award working on GWAS and post-GWAS characterisation of inflammation and disease: integrative analysis of genomes and phenomes in large epidemiological studies. Appointed October 2015.

Oliver Robinson, PhD MRC-PHE Centre for Environment and Health Early Career Research Fellowship working on Assessing the impact of the early life exposome on child growth and adiposity. Appointed April 2016. Primary supervisor Prof Paolo Vineis.

Deborah Schneider-Luftman, PhD UK MED-BIO Intermediate Research Fellowship award working on Multi-omics and epidemiologic data integration for disease mechanism research. Appointed June 2017.

Dr Xie Wuxiang Newton International Research Fellowship working on project on Dose–response relationship between air pollution and cardiovascular disease in Beijing. 1 Mar, 2016 – 28 Feb 2018.

Assessor for Wellcome Trust clinical PhD 4i programme at Imperial
Wellcome Trust clinical PhD 4i programme

Mentoring: academic mentor for the Academy of Medical Sciences mentorship scheme since 2012. Currently providing advice to 4 mid-career clinical scientists. 

Selected Publications

Journal Articles

Elliott P, Posma JM, Chan Q, et al., 2015, Urinary metabolic signatures of human adiposity, Science Translational Medicine, Vol:7, ISSN:1946-6234

More Publications