Imperial College London

DrPeterGatehouse

Faculty of MedicineNational Heart & Lung Institute

Honorary Senior Lecturer
 
 
 
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Contact

 

+44 (0)20 7351 8807p.gatehouse

 
 
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Location

 

MRISydney StreetRoyal Brompton Campus

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Summary

 

Summary


Thanks for looking. Current interests flow imaging and respiratory motion handling. The text below is obsolete but I left it there for the history of this field, as most people who built and used the old machinery have sadly now retired and that expertise no longer exists in clinical CMR centres like this.

I began in cardiac MRI around 1990 when it had an almost comically random quality if it hadn’t been so serious for some patients. It’s improved a bit since. I can’t honestly say that had anything to do with me. A strength of the Royal Brompton Hospital cardiac MRI centre is that it does only cardiac MRI, whereas many centres try a few cardiac scans a week and so they don't build up enough expertise among the clinical staff needed. The leadership of Professor Longmore who established this centre was inspiring. Another strength was essential in the earlier days: we modified the MRI scanners to improve their speed and flexibility for cardiac uses. This led to a dedicated cardiac MRI lab built in an old double-decker coach (avoiding planning permission for a new building).

The physics of MRI is amazingly flexible (even beautiful) if the electronics and software of the scanner is sufficiently open to modifications. On modern MRI systems we re-program how the images are acquired, to detect a range of different tissue properties. I remain most interested in the crazier forms of cardiac MRI (echo-planar imaging (EPI), spirals, locally selective imaging, hyperpolarized imaging) even if most busy clinicians understandably have no time for them. Otherwise I work on blood flow imaging. This is now a standard SIemens CMR site although we are very fortunate to have limited access to the scanner software under a research agreement with Erlangen, Germany.

 Unfortunately the drive to higher main field (3T) makes long-k-space paths more difficult and may limit interesting methods. Some centres are developing low-field magnets with fast gradient performance (a bit like our old 1992 "bus" CMR machine) and these are a very interesting topic for a young physicist - go find one of those (NIH Bethesda in USA mainly).  This department contains many other projects for example in imaging the structure of myocardial muscle using diffusion tensor imaging but is largely a busy routine clinical cardiac MRI service.

We always seek interested students. Even if it is just for vacation or gap-year work, please contact the appropriate head of section (Physics Dr Sonia Nielles-Vallespin or Medicine Prof Dudley Pennell).  If you receive no reply, thanks for applying and please accept our apologies, it's not you, it's often total overload (almost no placements in Summer 2021 for example).

 

Publications

Journals

Fair MJ, Gatehouse PD, Firmin DN, 2021, Minimisation of slab-selective radiofrequency excitation pulse durations constrained by an acceptable aliasing coefficient, Magnetic Resonance Imaging, Vol:81, ISSN:0730-725X, Pages:94-100

Bermejo IA, Bautista-Rodriguez C, Fraisse A, et al., 2021, Short-Term sequelae of Multisystem Inflammatory Syndrome in Children Assessed by CMR, Jacc-cardiovascular Imaging, Vol:14, ISSN:1936-878X, Pages:1666-1667

Raphael C, Mitchell F, Kanaganayagam G, et al., 2021, Cardiovascular magnetic resonance predictors of heart failure in hypertrophic cardiomyopathy: the role of myocardial replacement fibrosis and the microcirculation, Journal of Cardiovascular Magnetic Resonance, Vol:26, ISSN:1097-6647

Wu Y, Hatipoglu S, Alonso-Álvarez D, et al., 2021, Fast and automated segmentation for the three-directional multi-slice cine myocardial velocity mapping, Diagnostics, Vol:11, ISSN:2075-4418

Conference

Kuang M, Wu Y, Alonso-Álvarez D, et al., 2021, Three-dimensional embedded attentive RNN (3D-EAR) segmentor for leftventricle delineation from myocardial velocity mapping, arXiv

More Publications