Publications
245 results found
Vassiliou V, Heng EL, Sharma P, et al., 2015, Reproducibility of T1 mapping 11-heart beat MOLLI Sequence, Journal of Cardiovascular Magnetic Resonance, Pages: 1-3, ISSN: 1097-6647
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- Citations: 2
Wage R, Patel H, Smith GC, et al., 2015, The utility of magnetic resonance imaging in a trial to assess the effect of renal denervation in heart failure with preserved ejection fraction, Journal of Cardiovascular Magnetic Resonance, Pages: 1-2, ISSN: 1097-6647
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- Citations: 1
Fair M, Gatehouse P, Firmin D, 2015, Through-plane dark-rim artefacts in 3D first-pass myocardial perfusion, Journal of Cardiovascular Magnetic Resonance, Vol: 17, ISSN: 1532-429X
The dark-rim artefact (DRA) is well known in 2D first-pass perfusion (FPP). The in-plane features of DRA are understood, but DRA has not been examined along the second phase-encoding (partition) direction for 3D FPP. The Gibbs contribution to DRAs in 2D FPP is minimised by finer resolution, but low through-plane resolutions of 3D FPP imply risk of partition axis DRAs. We investigated these new partition DRAs ("PDRAs") and partial volume effects due to coarse resolution of this direction.
Vassiliou V, Heng EL, Donovan J, et al., 2015, Longitudinal stability of gel T1 MRI Phantoms for quality assurance of T1 mapping, Journal of Cardiovascular Magnetic Resonance, Vol: 17, ISSN: 1532-429X
Raphael CE, Hsu LY, Greve AM, et al., 2015, Wave intensity analysis and assessment of myocardial perfusion abnormalities in patients with hypertrophic cardiomyopathy, Journal of Cardiovascular Magnetic Resonance, Vol: 17, ISSN: 1097-6647
Heng EL, Kellman P, Gatzoulis MA, et al., 2015, Pilot data of right ventricular myocardial T1 quantification by free-breathing fat-water separated dark blood saturation-recovery imaging, Journal of Cardiovascular Magnetic Resonance, Pages: 1-2, ISSN: 1097-6647
Kellman P, Xue H, Spottiswoode BS, et al., 2015, Free-breathing T2*mapping using respiratory motion corrected averaging, JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE, Vol: 17, ISSN: 1097-6647
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- Citations: 26
Keegan J, Gatehouse PD, Haldar S, et al., 2015, Dynamic Inversion Time for Improved 3D Late Gadolinium Enhancement Imaging in Patients with Atrial Fibrillation, Magnetic Resonance in Medicine, Vol: 73, Pages: 646-654, ISSN: 1522-2594
Purpose—High resolution 3D late gadolinium enhancement (LGE) imaging is performed withsingle R-wave gating to minimise lengthy acquisition durations. In patients with atrial fibrillation(AF), heart rate variability results in variable magnetisation recovery between sequence repeatsand image quality is often poor. In this study, we implemented and tested a dynamic inversiontime scheme designed to reduce sequence sensitivity to heart rate variations.Methods—An inversion-prepared 3D segmented gradient echo sequence was modified so thatthe inversion time (TI) varied automatically from beat-to-beat (dynamic-TI) based on the timesince the last sequence repeat. 3D LGE acquisitions were performed in 17 patients prior to RFablation of persistent AF both with and without dynamic-TI. Qualitative image quality scores,blood signal-to-ghosting ratios (SGRs) and blood-myocardium contrast-to-ghosting ratios (CGRs)were compared.Results—Image quality scores were higher with dynamic-TI than without (2.2 +/− 0.9 versus 1.8+/− 1.1, p = 0.008) as were blood-myocardium CGRs (13.8 +/− 7.6 versus 8.3 +/− 6.1, p = 0.003)and blood SGRs (19.6 +/− 8.5 versus 13.1 +/− 8.0, p = 0.003).Conclusions—The dynamic-TI algorithm improves image quality of 3D LGE imaging in thisdifficult patient population by reducing the sequence sensitivity to RR interval variations.
Fair M, Gatehouse P, Firmin D, 2015, Through-plane dark-rim artefacts in 3D first-pass myocardial perfusion, Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, Vol: 17, ISSN: 1097-6647
Scott AD, Ferreira PFADC, Nielles-Vallespin S, et al., 2015, Optimal diffusion weighting for in vivo cardiac diffusion tensor imaging, Magnetic resonance in medicine, Vol: 74, Pages: 420-430
McGill L-A, Scott AD, Ferreira PF, et al., 2015, Heterogeneity of fractional anisotropy and mean diffusivity measurements by in vivo diffusion tensor imaging in normal human hearts, PloS one, Vol: 10, Pages: e0132360-e0132360
Ferreira PF, Kilner PJ, McGill L-A, et al., 2014, In vivo cardiovascular magnetic resonance diffusion tensor imaging shows evidence of abnormal myocardial laminar orientations and mobility in hypertrophic cardiomyopathy, Journal of Cardiovascular Magnetic Resonance, Vol: 16, Pages: 1-16, ISSN: 1097-6647
BackgroundCardiac diffusion tensor imaging (cDTI) measures the magnitudes and directions of intramyocardial water diffusion. Assuming the cross-myocyte components to be constrained by the laminar microstructures of myocardium, we hypothesized that cDTI at two cardiac phases might identify any abnormalities of laminar orientation and mobility in hypertrophic cardiomyopathy (HCM).MethodsWe performed cDTI in vivo at 3 Tesla at end-systole and late diastole in 11 healthy controls and 11 patients with HCM, as well as late gadolinium enhancement (LGE) for detection of regional fibrosis.ResultsVoxel-wise analysis of diffusion tensors relative to left ventricular coordinates showed expected transmural changes of myocardial helix-angle, with no significant differences between phases or between HCM and control groups. In controls, the angle of the second eigenvector of diffusion (E2A) relative to the local wall tangent plane was larger in systole than diastole, in accord with previously reported changes of laminar orientation. HCM hearts showed higher than normal global E2A in systole (63.9° vs 56.4° controls, p =0.026) and markedly raised E2A in diastole (46.8° vs 24.0° controls, p < 0.001). In hypertrophic regions, E2A retained a high, systole-like angulation even in diastole, independent of LGE, while regions of normal wall thickness did not (LGE present 57.8°, p =0.0028, LGE absent 54.8°, p =0.0022 vs normal thickness 38.1°).ConclusionsIn healthy controls, the angles of cross-myocyte components of diffusion were consistent with previously reported transmural orientations of laminar microstructures and their changes with contraction. In HCM, especially in hypertrophic regions, they were consistent with hypercontraction in systole and failure of relaxation in diastole. Further investigation of this finding is required as previously postulated effects of strain might be a confounding factor.
Ambrose N, Pierce IT, Gatehouse PD, et al., 2014, Magnetic resonance imaging of vein wall thickness in patients with Behcet's syndrome, CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, Vol: 32, Pages: S99-S102, ISSN: 0392-856X
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- Citations: 24
Simpson R, Keegan J, Gatehouse P, et al., 2014, Spiral Tissue Phase Velocity Mapping in a Breath-Hold with Non-Cartesian SENSE, MAGNETIC RESONANCE IN MEDICINE, Vol: 72, Pages: 659-668, ISSN: 0740-3194
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- Citations: 14
Nielles-Vallespin S, Mekkaoui C, Gatehouse P, et al., 2014, In Vivo Diffusion Tensor MRI of the Human Heart: Reproducibility of Breath-Hold and Navigator Based Approaches (vol 70, pg 454, 2013), MAGNETIC RESONANCE IN MEDICINE, Vol: 72, Pages: 599-599, ISSN: 0740-3194
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- Citations: 5
Simpson R, Keegan J, Gatehouse P, et al., 2014, Accelerating spiral tissue phase velocity mapping without affecting peak velocity measurements, Journal of Cardiovascular Magnetic Resonance, Vol: 16, ISSN: 1097-6647
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- Citations: 1
Ali A, Hsu LY, Gulati A, et al., 2014, The association between ECV and microcirculation perfusion abnormalities in non-ischemic dilated cardiomyopathy, Journal of Cardiovascular Magnetic Resonance, Vol: 16, ISSN: 1097-6647
Heng EL, Vassiliou V, Gatehouse P, et al., 2014, Temporal stability of gel relaxation-time phantoms for quality control of T1 and extracellular volume fraction measurements, Journal of Cardiovascular Magnetic Resonance, Vol: 16, Pages: P60-P60, ISSN: 1097-6647
Keegan J, Gatehouse P, Haldar S, et al., 2014, Improved 3D late gadolinium enhancement (LGE) imaging with dynamic-TI in patients with persistent atrial fibrillation, Journal of Cardiovascular Magnetic Resonance, Vol: 16, Pages: P6-P6, ISSN: 1097-6647
Simpson R, Keegan J, Gatehouse P, et al., 2014, Breath-hold spiral tissue phase velocity mapping (TPVM) with non-Cartesian SENSE, Journal of Cardiovascular Magnetic Resonance, Vol: 16, Pages: P40-P40, ISSN: 1097-6647
Fair M, Gatehouse P, Drivas P, et al., 2014, Method for correcting respiratory artefacts in parallel-accelerated first-pass myocardial perfusion imaging, Journal of Cardiovascular Magnetic Resonance, Vol: 16, Pages: P58-P58, ISSN: 1097-6647
Ismail TF, Hsu L-Y, Greve AM, et al., 2014, Coronary microvascular ischemia in hypertrophic cardiomyopathy-a pixel-wise quantitative cardiovascular magnetic resonance perfusion study, Journal of Cardiovascular Magnetic Resonance, Vol: 16, Pages: 49-49
Ferreira P, Kilner PJ, McGill L-A, et al., 2014, Aberrant myocardial sheetlet mobility in hypertrophic cardiomyopathy detected using in vivo cardiovascular magnetic resonance diffusion tensor imaging, Journal of Cardiovascular Magnetic Resonance, Vol: 16, Pages: P338-P338
Feng Y, He T, Gatehouse PD, et al., 2013, Improved MRI <i>R</i><sub>2</sub>* Relaxometry of Iron-Loaded Liver with Noise Correction, MAGNETIC RESONANCE IN MEDICINE, Vol: 70, Pages: 1765-1774, ISSN: 0740-3194
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- Citations: 52
Moon JC, Messroghli DR, Kellman P, et al., 2013, Myocardial T1 mapping and extracellular volume quantification: a Society for Cardiovascular Magnetic Resonance (SCMR) and CMR Working Group of the European Society of Cardiology consensus statement, JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE, Vol: 15, ISSN: 1097-6647
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- Citations: 750
Feng Y, He T, Carpenter J-P, et al., 2013, In vivo comparison of myocardial T1 with T2 and T2*in thalassaemia major, JOURNAL OF MAGNETIC RESONANCE IMAGING, Vol: 38, Pages: 588-593, ISSN: 1053-1807
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- Citations: 55
McGill L-A, Ismail T, Nielles-Vallespin S, et al., 2013, reproducibility of in-vivo diffusion tensor cardiovascular magnetic resonance in hypertrophic cardiomyopathy (vol 14, pg 86, 2012), JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE, Vol: 15, ISSN: 1097-6647
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- Citations: 2
Fair M, Gatehouse PD, Greiser A, et al., 2013, A novel approach to phase-contrast velocity offset correction by in vivo high-SNR acquisitions, Society for Cardiovascular Magnetic Resonance, Publisher: BioMed Central, ISSN: 1532-429X
Baseline offset errors on phase-contrast velocity imagescan be corrected using stationary tissue, for example sub-tracting fitted corrections from the image (1). Althoughcorrections are often curved over the FOV, 1st order(linear) fitting is typical. This may partly be due to lowSNR of static tissue making higher-order fitting unreli-able (2). Aim: To evaluate a new method acquiring addi-tional high SNR velocity images specifically to improveoffset correction.
Mekkaoui C, Nielles-Vallespin S, Jackowski MP, et al., 2013, Improving the accuracy of multi breath-hold diffusion tensor MRI tractography of the heart using dynamic motioncorrection, Journal of Cardiovascular Magnetic Resonance, Vol: 15, ISSN: 1097-6647
Ismail TF, Jabbour A, Gulati A, et al., 2013, Role of T1 and T2-mapping in assessing the myocardial interstitium in hypertrophic cardiomyopathy: a cardiovascular magnetic resonance study, Journal of Cardiovascular Magnetic Resonance, Vol: 15, ISSN: 1097-6647
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- Citations: 1
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