Imperial College London

DrPeterGatehouse

Faculty of MedicineNational Heart & Lung Institute

Honorary Clinical Senior Lecturer
 
 
 
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Contact

 

+44 (0)20 7351 8807p.gatehouse

 
 
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Location

 

MRISydney StreetRoyal Brompton Campus

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Summary

 

Publications

Publication Type
Year
to

245 results found

Kindler HE, Reyes E, Baksi AJ, Natarajan A, Alam H, Carpenter JP, Mohiaddin R, Gatehouse PD, Pennell Det al., 2013, Cardiac magnetic resonance perfusion imaging and the effects of single intravenous cannulation with the Octopus bionector, Journal of Cardiovascular Magnetic Resonance, Vol: 15, ISSN: 1097-6647

Journal article

Ali A, Gulati A, Ismail TF, Krishnathansan K, Ismail N, Nyktari E, Chahal N, Raphael CE, Wage R, He T, Gatehouse PD, Firmin D, Kellman P, Pennell D, Arai AE, Prasad SKet al., 2013, Quantitative assessment of myocardial extracellular volume fraction in non-ischemic dilated cardiomyopathy and its relation to systolic dysfunction, Journal of Cardiovascular Magnetic Resonance, Vol: 15, ISSN: 1097-6647

Journal article

McGill LA, Ismail T, Nielles-Vallespin S, Ferreira P, Scott AD, Roughton M, Kilner PJ, Ho SY, McCarthy KP, Gatehouse PD, de Silva R, Speier P, Feiweier T, Mekkaoui C, Sosnovik DE, Prasad SK, Firmin DN, Pennell DJet al., 2013, Correction: reproducibility of in-vivo diffusion tensor cardiovascular magnetic resonance in hypertrophic cardiomyopathy., J Cardiovasc Magn Reson, Vol: 15

Journal article

Fair M, Gatehouse PD, Greiser A, Drivas P, Firmin DNet al., 2013, A novel approach to phase-contrast velocity offset correction by in vivo high-SNR acquisitions, Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, Vol: 15, Pages: P56-P56, ISSN: 1097-6647

Journal article

Pierce I, Keegan J, Drivas P, Gatehouse PD, Firmin DNet al., 2013, Late gadolinium enhancement imaging using spiral readouts at 3T, Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, Vol: 15, Pages: E8-E8, ISSN: 1097-6647

Journal article

Ferreira PF, Nielles-Vallespin S, Gatehouse PD, de Silva R, Keegan J, Speier P, Feiweier T, Reese TG, Ismail TF, Scott A, otherset al., 2013, Improved navigator based diffusion tensor MRI of the human heart in vivo, Journal of Cardiovascular Magnetic Resonance, Vol: 15, Pages: W25-W25

Journal article

Ferreira PF, Nielles-Vallespin S, Gatehouse PD, de Silva R, Keegan J, Speier P, Feiweier T, Reese TG, Ismail TF, Scott A, otherset al., 2013, Cardiac diffusion tensor imaging: helix angle (HA) healthy statistical average technique for HA quantification in vivo, Journal of Cardiovascular Magnetic Resonance, Vol: 15, Pages: W7-W7

Journal article

Nielles-Vallespin S, Mekkaoui C, Gatehouse P, Reese TG, Keegan J, Ferreira PF, Collins S, Speier P, Feiweier T, Silva R, otherset al., 2013, In vivo diffusion tensor MRI of the human heart: Reproducibility of breath-hold and navigator-based approaches, Magnetic resonance in medicine, Vol: 70, Pages: 454-465

Journal article

Ferreira PF, Gatehouse PD, Mohiaddin RH, Firmin DNet al., 2013, Cardiovascular magnetic resonance artefacts, Journal of Cardiovascular Magnetic Resonance, Vol: 15, Pages: 41-41

Journal article

McGill L-A, Ismail TF, Nielles-Vallespin S, Ferreira P, Scott AD, Roughton M, Kilner PJ, Ho SY, McCarthy KP, Gatehouse PD, otherset al., 2012, Reproducibility of in-vivo diffusion tensor cardiovascular magnetic resonance in hypertrophic cardiomyopathy, Journal of Cardiovascular Magnetic Resonance, Vol: 14, Pages: 86-86, ISSN: 1097-6647

Background: Myocardial disarray is an important histological feature of hypertrophic cardiomyopathy (HCM) whichhas been studied post-mortem, but its in-vivo prevalence and extent is unknown. Cardiac Diffusion Tensor Imaging(cDTI) provides information on mean intravoxel myocyte orientation and potentially myocardial disarray. Recenttechnical advances have improved in-vivo cDTI, and the aim of this study was to assess the interstudyreproducibility of quantitative in-vivo cDTI in patients with HCM.Methods and results: A stimulated-echo single-shot-EPI sequence with zonal excitation and parallel imaging wasimplemented. Ten patients with HCM were each scanned on 2 different days. For each scan 3 short axismid-ventricular slices were acquired with cDTI at end systole. Fractional anisotropy (FA), mean diffusivity (MD), andhelix angle (HA) maps were created using a cDTI post-processing platform developed in-house. The mean ± SDglobal FA was 0.613 ± 0.044, MD was 0.750 ± 0.154 × 10-3 mm2/s and HA was epicardium −34.3 ± 7.6°,mesocardium 3.5 ± 6.9° and endocardium 38.9 ± 8.1°. Comparison of initial and repeat studies showed globalinterstudy reproducibility for FA (SD = ± 0.045, Coefficient of Variation (CoV) = 7.2%), MD (SD = ± 0.135 × 10-3 mm2/s,CoV = 18.6%) and HA (epicardium SD = ± 4.8°; mesocardium SD = ± 3.4°; endocardium SD = ± 2.9°). Reproducibilityof FA was superior to MD (p = 0.003). Global MD was significantly higher in the septum than the reference lateralwall (0.784 ± 0.188 vs 0.750 ± 0.154 x10-3 mm2/s, p < 0.001). Septal HA was significantly lower than the referencelateral wall in all 3 transmural layers (from −8.3° to −10.4°, all p < 0.001).Conclusions: To the best of our knowledge, this is the first study to assess the interstudy reproducibility of DTI inthe human HCM heart in-vivo and the largest cDTI stu

Journal article

Gatehouse PD, Rolf MP, Bloch KM, Kilner PJ, Graves MJ, Firmin DN, Hofman MBet al., 2012, A multi-center inter-manufacturer study of the temporal stability of phase-contrast velocity mapping background offset errors, Journal of Cardiovascular Magnetic Resonance, Vol: 14

Journal article

Nielles-Vallespin S, Mekkaoui C, Gatehouse PD, Reese TG, Keegan J, Collins S, Speier P, Feiweier T, Jackowski MP, Sosnovik DE, Firmin DNet al., 2012, Diffusion tensor MRI of the human heart In Vivo with a navigator based free breathing approach, Journal of Cardiovascular Magnetic Resonance, Vol: 14

Journal article

Keegan J, Gatehouse PD, Babu-Naryanan SV, Wage R, Firmin DNet al., 2012, Dynamic TI for late gadolinium enhancement imaging in atrial fibrillation, Journal of Cardiovascular Magnetic Resonance, Vol: 14

Journal article

Simpson R, Keegan J, Gatehouse PD, Firmin DNet al., 2012, Retrogated spiral 3-directional myocardial phase velocity mapping in a single breath-hold, Journal of Cardiovascular Magnetic Resonance, Vol: 14

Journal article

Gatehouse PD, Rolf MP, Bloch KM, Graves MJ, Kilner PJ, Firmin DN, Hofman MBMet al., 2012, A multi-center inter-manufacturer study of the temporal stability of phase-contrast velocity mapping background offset errors, JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE, Vol: 14, ISSN: 1097-6647

Journal article

Ferreira PF, Gatehouse PD, Firmin DN, 2012, Myocardial first-pass perfusion imaging with hybrid-EPI: frequency-offsets and potential artefacts, Journal of Cardiovascular Magnetic Resonance, Vol: 14, Pages: 44-44, ISSN: 1097-6647

BackgroundFirst-pass myocardial perfusion is often imaged with a tailored hybrid centric interleaved echo-planar-imaging sequence, providing rapid image acquisition with good contrast enhancement. The centric interleaved phase-encode order minimises the effective time-of-echo but it is sensitive to frequency-offsets. This short article aims to show possible artefacts that might originate with this sequence, in the context of first-pass perfusion imaging, when frequency-offsets are present. Non-uniform magnitude modulation effects were also analysed.MethodsNumerical and phantom simulations were used to illustrate the effects of frequency-offsets and non-uniform magnitude modulation with this sequence in a typical perfusion protocol. In vivo data was post-processed to analyse the h-EPI’s sensitivity to the frequency-offsets.ResultsThe centric phase-order was shown to be highly sensitive to frequency-offsets due to its symmetrical phase slope. Resulting artefacts include blurring, and splitting of the image into two identical copies along the phase-encode direction. It was also shown that frequency-offsets can introduce signal loss and ghosting of the right ventricle signal into the myocardium. The in vivo results were confirmed by numerical and phantom simulations. Magnitude modulation effects were found to be small.ConclusionsImaging first-pass myocardial perfusion with an hybrid centric echo-planar-imaging sequence can be corrupted with ghosting and splitting of the image due to frequency-offsets.

Journal article

Feng Y, Gatehouse PD, Liu P, Carpenter JP, Pennell DJ, Firmin DN, Chen W, He Tet al., 2012, On optimal liver T2* measurement: Region of interest or pixel-wise?, Journal of Cardiovascular Magnetic Resonance, Vol: 14, ISSN: 1097-6647

Journal article

Mekkaoui C, Nielles-Vallespin S, Gatehouse PD, Jackowski MP, Firmin DN, Sosnovik DEet al., 2012, Diffusion MRI tractography of the human heart In Vivo at end-diastole and end-systole, Journal of Cardiovascular Magnetic Resonance, Vol: 14, ISSN: 1097-6647

Journal article

Gatehouse PD, Greiser A, Firmin DN, 2012, Effects from RF spoiling disequilibrium in the background offsets of phase-contrast velocity imaging, Journal of Cardiovascular Magnetic Resonance, Vol: 14, ISSN: 1097-6647

Journal article

Gatehouse PD, Firmin DN, 2012, Field-of-view zoom during a single-shot short-axis image for cardiac contraction correction, Journal of Cardiovascular Magnetic Resonance, Vol: 14, ISSN: 1097-6647

Journal article

Pierce IT, Gatehouse PD, Firmin DN, 2012, In-vivo distortion of through-plane flow by spiral phase-contrast imaging, Journal of Cardiovascular Magnetic Resonance, Vol: 14, ISSN: 1097-6647

Journal article

Simpson R, Keegan J, Gatehouse PD, Firmin DNet al., 2012, Retrogated spiral 3-directional myocardial phase velocity mapping in a single breath-hold, Journal of Cardiovascular Magnetic Resonance, Vol: 14, ISSN: 1097-6647

Journal article

Wang Y, Pierce I, Gatehouse P, Wood N, Firmin D, Xu XYet al., 2012, Analysis of flow and wall shear stress in the peroneal veins under external compression based on real-time MR images, MEDICAL ENGINEERING & PHYSICS, Vol: 34, Pages: 17-27, ISSN: 1350-4533

Journal article

Pierce IT, Gatehouse PD, Kalodiki E, Lattimer C, Geroulakos G, Xu XY, Firmin DNet al., 2012, Magnetic resonance venous velocity mapping during intermittent pneumatic compression of the calf and foot, Phlebology, Vol: 27, Pages: 352-359

Journal article

De Luca A, Warboys CM, Amini N, Ferreira P, Gatehouse P, Firmin D, Mason J, Sherwin S, Evans PCet al., 2012, IMAGE-BASED COMPUTATIONAL HEMODYNAMICS AND MICROARRAY ANALYSIS OF THE PORCINE AORTIC ARCH REVEALS A CORRELATION BETWEEN SHEAR STRESS AND ENDOTHELIAL CELL APOPTOSIS, PROCEEDINGS OF THE ASME SUMMER BIOENGINEERING CONFERENCE, PTS A AND B, Pages: 923-924

Journal article

Pierce IT, Gatehouse PD, Xu XY, Firmin DNet al., 2011, MR Phase-Contrast Velocity Mapping Methods for Measuring Venous Blood Velocity in the Deep Veins of the Calf, JOURNAL OF MAGNETIC RESONANCE IMAGING, Vol: 34, Pages: 634-644, ISSN: 1053-1807

Journal article

Rolf MP, Hofman MBM, Gatehouse PD, Markenroth-Bloch K, Heymans MW, Ebbers T, Graves MJ, Totman JJ, Werner B, van Rossum AC, Kilner PJ, Heethaar RMet al., 2011, Sequence optimization to reduce velocity offsets in cardiovascular magnetic resonance volume flow quantification - A multi-vendor study, JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE, Vol: 13, ISSN: 1097-6647

Journal article

Hsu LY, Kellman P, Gatehouse P, Zuehlsdorff S, Glielmi CB, Groves DW, Aletras AH, Bandettini PW, Arai AEet al., 2011, Comparison of arterial input function measured from dual-bolus and dual-sequence dynamic contrast-enhanced cardiac magnetic resonance imaging, Journal of Cardiovascular Magnetic Resonance, Vol: 13, ISSN: 1097-6647

Journal article

, 2010, Eleventh Meeting of the European Venous Forum: Antwerp, Belgium, 24-26 June 2010, PHLEBOLOGY, Vol: 25, Pages: 296-311, ISSN: 0268-3555

Journal article

Bucciarelli-Ducci C, Locca D, O'hanlon R, Grasso A, Petryka J, Wright C, Symmonds K, Gatehouse P, Di Mario C, Pennell DJet al., 2010, Recanalization of coronary chronic total occlusion guided by cardiovascular magnetic resonance imaging and its relation with health outcome measures, ESC Congress, Publisher: OXFORD UNIV PRESS, Pages: 983-983, ISSN: 0195-668X

Conference paper

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