Imperial College London
Alternate

ProfessorPaulLangford

Faculty of Medicine, Department of Infectious Disease

Professor of Paediatric Infectious Diseases
 
 
 
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Contact

 

+44 (0)20 7594 3359p.langford Website

 
 
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Location

 

236Wright Fleming WingSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Langford:2021:10.1017/S1466252321000074,
author = {Langford, P and Stringer, O and Li, Y and Bosse, J},
doi = {10.1017/S1466252321000074},
journal = {Animal Health Research Reviews},
pages = {120--135},
title = {Application of the MISTEACHING(S) disease susceptibility framework to Actinobacillus pleuropneumoniae to identify research gaps: an exemplar of a veterinary pathogen},
url = {http://dx.doi.org/10.1017/S1466252321000074},
volume = {22},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Historically, the MISTEACHING (microbiome, immunity, sex, temperature, environment, age, chance, history, inoculum, nutrition, genetics) framework to describe the outcome of host-pathogen interaction, has been applied to human pathogens. Here, weshow, using Actinobacillus pleuropneumoniaeas an exemplar, that the MISTEACHING framework can be applied to a strict veterinary pathogen enabling the identification of major research gaps, and the formulation of hypotheses whose study will lead to a greater understanding of pathogenic mechanisms, and/or improved prevention/therapeutic measures. We also suggest that the MISTEACHING framework should be extended with the inclusion of a “strain” category, to become MISTEACHINGS. We conclude that the MISTEACHINGS framework can be applied to veterinary pathogens, whether they be bacteria, viruses, or parasites, and hope to stimulate others to use it to identify research gaps and to formulate hypotheses worthy of study with their own pathogens.
AU  - Langford,P
AU  - Stringer,O
AU  - Li,Y
AU  - Bosse,J
DO  - 10.1017/S1466252321000074
EP  - 135
PY  - 2021///
SN  - 1466-2523
SP  - 120
TI  - Application of the MISTEACHING(S) disease susceptibility framework to Actinobacillus pleuropneumoniae to identify research gaps: an exemplar of a veterinary pathogen
T2  - Animal Health Research Reviews
UR  - http://dx.doi.org/10.1017/S1466252321000074
UR  - http://hdl.handle.net/10044/1/90118
VL  - 22
ER  -
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