Imperial College London

Professor Paul M. Matthews

Faculty of MedicineDepartment of Brain Sciences

Edmond and Lily Safra Chair, Head of Department
 
 
 
//

Contact

 

+44 (0)20 7594 2855p.matthews

 
 
//

Assistant

 

Ms Siobhan Dillon +44 (0)20 7594 2855

 
//

Location

 

E502Burlington DanesHammersmith Campus

//

Summary

 

Publications

Publication Type
Year
to

608 results found

Motallebzadeh R, Jahangiri M, 2005, Distinguishing solid from gaseous emboli during cardiac surgery, JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, Vol: 129, Pages: 1194-1194, ISSN: 0022-5223

Journal article

Abu-Omar Y, Matthews PM, Taggart DP, 2005, Distinguishing solid from gaseous emboli during cardiac surgery - Reply, JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, Vol: 129, Pages: 1194-1195, ISSN: 0022-5223

Journal article

Zarei M, Johansen-Berg J, Ramnani N, Matthews PMet al., 2005, In vivo mapping of cortical connections in the human internal capsule and its implication in functional recovery after stroke, Sino-British Joint Conference on Neurology, Publisher: B M J PUBLISHING GROUP, Pages: 605-605, ISSN: 0022-3050

Conference paper

Voets NL, Matthews PM, 2005, Clinical applications of functional magnetic resonance imaging, Imaging Decisions MRI, Vol: 9, Pages: 16-22, ISSN: 1433-3317

Blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) provides a new tool for neuroradiology. The BOLD fMRI allows functional changes to be distinguished, even in the absence of structural changes in the brain. Up until now, routine clinical applications largely have been limited to localizing eloquent brain regions in pre-surgical planning. However, in exploratory applications, the method has allowed new insights into mechanisms of brain plasticity, helping clinicians better appreciate its importance in recovery after brain injury. Several new areas of application may be anticipated based on current research work, including for pre-symptomatic disease detection, testing drug dose-activity relationships, and the diagnosis and characterization of somatization disorders. A major direction of methodological research is towards integration of fMRI with other techniques, particularly electrophysiological methods. The emphasis that these new approaches to imaging will place on understanding functional changes associated with disease challenges current neuroradiological training and service delivery models. They emphasize the need to develop closer relationship between neuroradiology and the traditional clinical neurosciences.

Journal article

Smith SM, Beckmann CF, Ramnani N, Woolrich MW, Bannister PR, Jenkinson M, Matthews PM, McGonigle DJet al., 2005, Variability in fMRI: A re-examination of inter-session differences, HUMAN BRAIN MAPPING, Vol: 24, Pages: 248-257, ISSN: 1065-9471

Journal article

Johansen-Berg H, Behrens TEJ, Sillery E, Ciccarelli O, Thompson AJ, Smith SM, Matthews PMet al., 2005, Functional-anatomical validation and individual variation of diffusion tractography-based segmentation of the human thalamus, CEREBRAL CORTEX, Vol: 15, Pages: 31-39, ISSN: 1047-3211

Journal article

Pomeroy IM, Esiri MM, Matthews PM, Palace Jet al., 2005, Typical cortical lesions in an animal model of MS, Autumn Meeting of the Association-of-British-Neurologists, Publisher: B M J PUBLISHING GROUP, Pages: 152-152, ISSN: 0022-3050

Conference paper

Wegner C, Esiri MM, Palace J, Matthews PMet al., 2005, Synaptic loss and impaired synaptic plasticity in cortical lesions of multiple sclerosis, Autumn Meeting of the Association-of-British-Neurologists, Publisher: B M J PUBLISHING GROUP, Pages: 152-152, ISSN: 0022-3050

Conference paper

Olivers CNL, Smith S, Matthews P, Humphreys GWet al., 2005, Prioritizing new over old: An fMRI study of the preview search task, HUMAN BRAIN MAPPING, Vol: 24, Pages: 69-78, ISSN: 1065-9471

Journal article

Devlin JT, Rushworth MFS, Matthews PM, 2005, Category-related activation for written words in the posterior fusiform is task specific, NEUROPSYCHOLOGIA, Vol: 43, Pages: 69-74, ISSN: 0028-3932

Journal article

Bridge H, Clare S, Jenkinson M, Jezzard P, Parker AJ, Matthews PMet al., 2005, Independent anatomical and functional measures of the V1/V2 boundary in human visual cortex, JOURNAL OF VISION, Vol: 5, Pages: 93-102, ISSN: 1534-7362

Journal article

Austin VC, Blamire AM, Allers KA, Sharp T, Styles P, Matthews PM, Sibson NRet al., 2005, Confounding effects of anesthesia on functional activation in rodent brain: a study of halothane and alpha-chloralose anesthesia, NEUROIMAGE, Vol: 24, Pages: 92-100, ISSN: 1053-8119

Journal article

Devlin JT, Watkins KE, Sillery EL, Behrens TEJ, Johansen-Berg H, Nunes RG, Clare S, Matthews PMet al., 2005, Distinct fronto-temporal pathways mediate semantic and phonological processing, 12th Annnual Meeting of the Cognitive-Neuroscience-Society, Publisher: M I T PRESS, Pages: 43-43, ISSN: 0898-929X

Conference paper

Matthews PM, Johansen-Berg H, Reddy H, 2004, Non-invasive mapping of brain functions and brain recovery: Applying lessons from cognitive neuroscience to neurorehabilitation, Restorative Neurology and Neuroscience, Vol: 22, Pages: 245-260, ISSN: 0922-6028

Modern cognitive neuroscience provides a powerful framework in which biological models of recovery and neurorehabilitation can be constructed and tested. The widespread availability, relatively low cost and informativeness of functional magnetic resonance imaging (fMRI) has made it the most popular of the techniques available to help with this task. Here, on the basis of functional imaging studies of stroke, diffuse microvascular disease and multiple sclerosis, we argue that processes of motor control and learning in the healthy brain share common mechanisms with those for adaptive functional reorganisation during spontaneous recovery after brain injury or with neurorehabilitation. Relatively stringent criteria can be met to confirm that adaptive functional reorganisation limits disability even in the adult brain: functional brain changes are related to disease burden, can be found in patients with demonstrable pathology but no clinical deficits and can be defined (in motor cortex) even in the absence of volitional recruitment. Initial studies of neurorehabilitation responses using fMRI and transcranial magnetic stimulation demonstrate that adaptive reorganisation can be manipulated directly with both pharmacological and behavioural interventions. The combination of strategies based on a strong biological rational with monitoring their effects using highly informative functional brain imaging methods heralds a new era of scientifically-founded neurorehabilitation.

Journal article

Luthi A, Wikstrom MA, Palmer MJ, Matthews P, Benke TA, Isaac JTR, Collingridge GLet al., 2004, Bi-directional modulation of AMPA receptor unitary conductance by synaptic activity, BMC NEUROSCIENCE, Vol: 5, ISSN: 1471-2202

Journal article

Chen JT, Narayanan S, Collins DL, Smith SM, Matthews PM, Arnold DLet al., 2004, Relating neocortical pathology to disability progression in multiple sclerosis using MRI, NEUROIMAGE, Vol: 23, Pages: 1168-1175, ISSN: 1053-8119

Journal article

Ramnani N, Behrens TEJ, Penny W, Matthews PMet al., 2004, New approaches for exploring anatomical and functional connectivity in the human brain, BIOLOGICAL PSYCHIATRY, Vol: 56, Pages: 613-619, ISSN: 0006-3223

Journal article

Cardillo ER, Aydelott J, Matthews PM, Devlin JTet al., 2004, Left inferior prefrontal cortex activity reflects inhibitory rather than facilitatory priming, JOURNAL OF COGNITIVE NEUROSCIENCE, Vol: 16, Pages: 1552-1561, ISSN: 0898-929X

Journal article

Abu-Omar Y, Cader MZ, Balacumaraswami L, Matthews PM, Taggart DPet al., 2004, Cerebral injury following on-pump and off-pump cardiac surgery defined by functional magnetic resonance imaging, 77th Scientific Meeting of the American-Heart-Association, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 547-547, ISSN: 0009-7322

Conference paper

Devlin JT, Jamison HL, Matthews PM, Gonnerman LMet al., 2004, Morphology and the internal structure of words, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 101, Pages: 14984-14988, ISSN: 0027-8424

Journal article

Floyer-Lea A, Matthews PM, 2004, Changing brain networks for visuomotor control with increased movement automaticity, JOURNAL OF NEUROPHYSIOLOGY, Vol: 92, Pages: 2405-2412, ISSN: 0022-3077

Journal article

Bannerman DM, Matthews P, Deacon RMJ, Rawlins JNPet al., 2004, Medial septal lesions mimic effects of both selective dorsal and ventral hippocampal lesions, BEHAVIORAL NEUROSCIENCE, Vol: 118, Pages: 1033-1041, ISSN: 0735-7044

Journal article

Johansen-Berg H, Behrens TEJ, Robson MD, Drobnjak I, Rushworth MFS, Brady JM, Smith SM, Higham DJ, Matthews PMet al., 2004, Changes in connectivity profiles define functionally distinct regions in human medial frontal cortex, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 101, Pages: 13335-13340, ISSN: 0027-8424

Journal article

Abu-Omar Y, Cifelli A, Matthews PM, Taggart DPet al., 2004, The role of microembolisation in cerebral injury as defined by functional magnetic resonance imaging, EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, Vol: 26, Pages: 586-590, ISSN: 1010-7940

Journal article

Vollm BA, de Araujo IE, Cowen PJ, Rolls ET, Kringelbach ML, Smith KA, Jezzard P, Heal RJ, Matthews PMet al., 2004, Methamphetamine activates reward circuitry in drug naive human subjects, NEUROPSYCHOPHARMACOLOGY, Vol: 29, Pages: 1715-1722, ISSN: 0893-133X

Journal article

Matthews PM, 2004, Primary progressive multiple sclerosis takes centre stage, JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol: 75, Pages: 1232-1233, ISSN: 0022-3050

Journal article

Cader MZ, Cifelli A, Abu-Omar Y, Palace J, Matthews PMet al., 2004, A verbal working memory task reveals new differences in the activation pattern of multiple sclerosis patients compared with healthy controls, 20th Congress of the European-Committee-for-Treatment-and-Research-in-Multiple- Sclerosis/9th Annual Meeting of Rehabilitation in MS, Publisher: ARNOLD, HODDER HEADLINE PLC, Pages: S102-S103, ISSN: 1352-4585

Conference paper

Miller DH, Filippi M, Fazekas F, Frederiksen JL, Matthews PM, Montalban X, Polman CHet al., 2004, Role of magnetic resonance imaging within diagnostic criteria for multiple sclerosis, ANNALS OF NEUROLOGY, Vol: 56, Pages: 273-278, ISSN: 0364-5134

Journal article

Matthews PM, 2004, An update on neuroimaging of multiple sclerosis, CURRENT OPINION IN NEUROLOGY, Vol: 17, Pages: 453-458, ISSN: 1350-7540

Journal article

Arthurs OJ, Johansen-Berg H, Matthews PM, Boniface SJet al., 2004, Attention differentially modulates the coupling of fMRI BOLD and evoked potential signal amplitudes in the human somatosensory cortex, EXPERIMENTAL BRAIN RESEARCH, Vol: 157, Pages: 269-274, ISSN: 0014-4819

Journal article

This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.

Request URL: http://wlsprd.imperial.ac.uk:80/respub/WEB-INF/jsp/search-html.jsp Request URI: /respub/WEB-INF/jsp/search-html.jsp Query String: id=00501273&limit=30&person=true&page=13&respub-action=search.html