Imperial College London

Professor Paul M. Matthews

Faculty of MedicineDepartment of Medicine

Edmond and Lily Safra Chair and Head of Brain Sciences
 
 
 
//

Contact

 

+44 (0)20 7594 2855p.matthews

 
 
//

Assistant

 

Ms Siobhan Dillon +44 (0)20 7594 2855

 
//

Location

 

E502Burlington DanesHammersmith Campus

//

Summary

 

Publications

Publication Type
Year
to

582 results found

Zarei M, Patenaude B, Damoiseaux J, Morgese C, Smith S, Matthews PM, Barkhof F, Rombouts SARB, Sanz-Arigita E, Jenkinson Met al., 2010, Combining shape and connectivity analysis: An MRI study of thalamic degeneration in Alzheimer's disease (vol 49, pg 1, 2010), NEUROIMAGE, Vol: 51, Pages: 940-940, ISSN: 1053-8119

JOURNAL ARTICLE

Heinzen EL, Radtke RA, Urban TJ, Cavalleri GL, Depondt C, Need AC, Walley NM, Nicoletti P, Ge D, Catarino CB, Duncan JS, Kasperaviciute D, Tate SK, Caboclo LO, Sander JW, Clayton L, Linney KN, Shianna KV, Gumbs CE, Smith J, Cronin KD, Maia JM, Doherty CP, Pandolfo M, Leppert D, Middleton LT, Gibson RA, Johnson MR, Matthews PM, Hosford D, Kalviainen R, Eriksson K, Kantanen A-M, Dorn T, Hansen J, Kraemer G, Steinhoff BJ, Wieser H-G, Zumsteg D, Ortega M, Wood NW, Huxley-Jones J, Mikati M, Gallentine WB, Husain AM, Buckley PG, Stallings RL, Podgoreanu MV, Delanty N, Sisodiya SM, Goldstein DBet al., 2010, Rare Deletions at 16p13.11 Predispose to a Diverse Spectrum of Sporadic Epilepsy Syndromes, AMERICAN JOURNAL OF HUMAN GENETICS, Vol: 86, Pages: 707-718, ISSN: 0002-9297

JOURNAL ARTICLE

Pomeroy IM, Jordan EK, Frank JA, Matthews PM, Esiri MMet al., 2010, Focal and diffuse cortical degenerative changes in a marmoset model of multiple sclerosis, MULTIPLE SCLEROSIS JOURNAL, Vol: 16, Pages: 537-548, ISSN: 1352-4585

JOURNAL ARTICLE

Matthews PM, 2010, IMAGING FOR TRANSLATIONAL PHARMACOLOGY, IRISH JOURNAL OF MEDICAL SCIENCE, Vol: 179, Pages: S99-S100, ISSN: 0021-1265

JOURNAL ARTICLE

Zarei M, Patenaude B, Damoiseaux J, Morgese C, Smith S, Matthews PM, Barkhof F, Rombouts S, Sanz-Arigita E, Jenkinson Met al., 2010, Combining shape and connectivity analysis: An MRI study of thalamic degeneration in Alzheimer's disease, NEUROIMAGE, Vol: 49, Pages: 1-8, ISSN: 1053-8119

JOURNAL ARTICLE

Tzimopoulou S, Cunningham VJ, Nichols TE, Searle G, Bird NP, Mistry P, Dixon IJ, Hallett WA, Whitcher B, Brown AP, Zvartau-Hind M, Lotay N, Lai RYK, Castiglia M, Jeter B, Matthews JC, Chen K, Bandy D, Reiman EM, Gold M, Rabiner EA, Matthews PMet al., 2010, A Multi-Center Randomized Proof-of-Concept Clinical Trial Applying [F-18]FDG-PET for Evaluation of Metabolic Therapy with Rosiglitazone XR in Mild to Moderate Alzheimer's Disease, JOURNAL OF ALZHEIMERS DISEASE, Vol: 22, Pages: 1241-1256, ISSN: 1387-2877

JOURNAL ARTICLE

Antoniades A, Matthews PM, Pattichis CS, Galwey NWet al., 2010, A Computationally Fast Measure Of Epistasis For 2 SNPs And A Categorical Phenotype, 2010 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC), Pages: 6194-6197, ISSN: 1557-170X

JOURNAL ARTICLE

Giorgio A, Watkins KE, Chadwick M, James S, Winmill L, Douaud G, De Stefano N, Matthews PM, Smith SM, Johansen-Berg H, James ACet al., 2010, Longitudinal changes in grey and white matter during adolescence, NEUROIMAGE, Vol: 49, Pages: 94-103, ISSN: 1053-8119

JOURNAL ARTICLE

Nalbantian S, Matthews PM, McClelland JL, 2010, The Memory Process, Publisher: Mit Pr, ISBN: 9780262014571

The convergence of neuroscience, philosophy, art, music, and literature offers valuablenew insights into the study of memory.

BOOK

Voets NL, Adcock JE, Stacey R, Hart Y, Carpenter K, Matthews PM, Beckmann CFet al., 2009, Functional and Structural Changes in the Memory Network Associated with Left Temporal Lobe Epilepsy, HUMAN BRAIN MAPPING, Vol: 30, Pages: 4070-4081, ISSN: 1065-9471

JOURNAL ARTICLE

Tomassini V, Johansen-Berg H, Leonardi L, Palace J, Pozzilli C, Matthews PMet al., 2009, MOTOR SKILL LEARNING IN MULTIPLE SCLEROSIS, Joint Annual Meeting of the Association-of-British-Neurologists/Spanish-Society-of-Neurology, Publisher: BMJ PUBLISHING GROUP, ISSN: 0022-3050

CONFERENCE PAPER

Matthews PM, Comley R, 2009, Advances in the molecular imaging of multiple sclerosis, EXPERT REVIEW OF CLINICAL IMMUNOLOGY, Vol: 5, Pages: 765-777, ISSN: 1744-666X

JOURNAL ARTICLE

Matthews PM, 2009, Pharmacological applications of fMRI, ISBN: 9781603279185

Modern drug development presents new challenges by the unmet medical needs of chronic neurological and psychiatric disease. Imaging provides a potentially powerful tool for more efficiently translating pre-clinical and clinical studies and enhancing confidence in progression through early phase clinical development. Pharmacological MRI (phMRI) refers specifically to the applications of fMRI methods for direct or indirect measures of drug action. phMRI can be coupled to advanced structural methods to relate pharmacological effects and functional anatomy. Current and potential applications of phMRI to target stratification, patient validation, and pharmacodynamic studies are described. While great new opportunities could arise from extension of these methods as surrogate markers of clinical responses, this review highlights the substantial additional work that would need to be done to make this feasible. The review concludes that there is a strong rational for investment in phMRI for early phase clinical development, but that the short- to medium-term impact on late phase clinical development likely will be modest. © 2009 Humana Press.

BOOK

Zarei M, Menke RA, Scholz J, Miller K, Deoni S, Jbabdi S, Matthews PMet al., 2009, Multimodal MR imaging of substantia nigra in Parkinson's disease, 19th World Congress of Neurology, Publisher: ELSEVIER SCIENCE BV, Pages: S293-S293, ISSN: 0022-510X

CONFERENCE PAPER

Stagg CJ, O'Shea J, Kincses ZT, Woolrich M, Matthews PM, Johansen-Berg Het al., 2009, Modulation of movement-associated cortical activation by transcranial direct current stimulation, EUROPEAN JOURNAL OF NEUROSCIENCE, Vol: 30, Pages: 1412-1423, ISSN: 0953-816X

JOURNAL ARTICLE

Douaud G, Mackay C, Andersson J, James S, Quested D, Ray MK, Connell J, Roberts N, Crow TJ, Matthews PM, Smith S, James Aet al., 2009, Schizophrenia delays and alters maturation of the brain in adolescence, BRAIN, Vol: 132, Pages: 2437-2448, ISSN: 0006-8950

JOURNAL ARTICLE

Menke RA, Scholz J, Miller KL, Deoni S, Jbabdi S, Matthews PM, Zarei Met al., 2009, MRI characteristics of the substantia nigra in Parkinson's disease: A combined quantitative T1 and DTI study, NEUROIMAGE, Vol: 47, Pages: 435-441, ISSN: 1053-8119

JOURNAL ARTICLE

Stefansson H, Ophoff RA, Steinberg S, Andreassen OA, Cichon S, Rujescu D, Werge T, Pietilainen OPH, Mors O, Mortensen PB, Sigurdsson E, Gustafsson O, Nyegaard M, Tuulio-Henriksson A, Ingason A, Hansen T, Suvisaari J, Lonnqvist J, Paunio T, Borglum AD, Hartmann A, Fink-Jensen A, Nordentoft M, Hougaard D, Norgaard-Pedersen B, Bottcher Y, Olesen J, Breuer R, Moeller H-J, Giegling I, Rasmussen HB, Timm S, Mattheisen M, Bitter I, Rethelyi JM, Magnusdottir BB, Sigmundsson T, Olason P, Mason G, Gulcher JR, Haraldsson M, Fossdal R, Thorgeirsson TE, Thorsteinsdottir U, Ruggeri M, Tosato S, Franke B, Strengman E, Kiemeney LA, Melle I, Djurovic S, Abramova L, Kaleda V, Sanjuan J, de Frutos R, Bramon E, Vassos E, Fraser G, Ettinger U, Picchioni M, Walker N, Toulopoulou T, Need AC, Ge D, Yoon JL, Shianna KV, Freimer NB, Cantor RM, Murray R, Kong A, Golimbet V, Carracedo A, Arango C, Costas J, Joensson EG, Terenius L, Agartz I, Petursson H, Nothen MM, Rietschel M, Matthews PM, Muglia P, Peltonen L, St Clair D, Goldstein DB, Stefansson K, Collier DAet al., 2009, Common variants conferring risk of schizophrenia, NATURE, Vol: 460, Pages: 744-U99, ISSN: 0028-0836

JOURNAL ARTICLE

Rocca MA, Absinta M, Valsasina P, Ciccarelli O, Marino S, Rovira A, Gass A, Wegner C, Enzinger C, Korteweg T, Sormani MP, Mancini L, Thompson AJ, De Stefano N, Montalban X, Hirsch J, Kappos L, Ropele S, Palace J, Barkhof F, Matthews PM, Filippi Met al., 2009, Abnormal Connectivity of the Sensorimotor Network in Patients With MS: A MultiCenter fMRI Study, HUMAN BRAIN MAPPING, Vol: 30, Pages: 2412-2425, ISSN: 1065-9471

JOURNAL ARTICLE

Cader S, Palace J, Matthews PM, 2009, Cholinergic agonism alters cognitive processing and enhances brain functional connectivity in patients with multiple sclerosis, JOURNAL OF PSYCHOPHARMACOLOGY, Vol: 23, Pages: 686-696, ISSN: 0269-8811

JOURNAL ARTICLE

Inkster B, Nichols TE, Saemann PG, Auer DP, Holsboer F, Muglia P, Matthews PMet al., 2009, Association of GSK3 beta Polymorphisms With Brain Structural Changes in Major Depressive Disorder, ARCHIVES OF GENERAL PSYCHIATRY, Vol: 66, Pages: 721-728, ISSN: 0003-990X

JOURNAL ARTICLE

De Jager PL, Jia X, Wang J, de Bakker PIW, Ottoboni L, Aggarwal NT, Piccio L, Raychaudhuri S, Tran D, Aubin C, Briskin R, Romano S, Baranzini SE, McCauley JL, Pericak-Vance MA, Haines JL, Gibson RA, Naeglin Y, Uitdehaag B, Matthews PM, Kappos L, Polman C, McArdle WL, Strachan DP, Evans D, Cross AH, Daly MJ, Compston A, Sawcer SJ, Weiner HL, Hauser SL, Hafler DA, Oksenberg JRet al., 2009, Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci, NATURE GENETICS, Vol: 41, Pages: 776-U26, ISSN: 1061-4036

JOURNAL ARTICLE

Enzinger C, Dawes H, Johansen-Berg H, Wade D, Bogdanovic M, Collett J, Guy C, Kischka U, Ropele S, Fazekas F, Matthews PMet al., 2009, Brain Activity Changes Associated With Treadmill Training After Stroke, STROKE, Vol: 40, Pages: 2460-2467, ISSN: 0039-2499

JOURNAL ARTICLE

Stagg CJ, Wylezinska M, Matthews PM, Johansen-Berg H, Jezzard P, Rothwell JC, Bestmann Set al., 2009, Neurochemical Effects of Theta Burst Stimulation as Assessed by Magnetic Resonance Spectroscopy, JOURNAL OF NEUROPHYSIOLOGY, Vol: 101, Pages: 2872-2877, ISSN: 0022-3077

JOURNAL ARTICLE

Filippi M, Rocca MA, Absinta M, Valsasina P, Ciccarelli O, Marino S, Rovira A, Gass A, Wegner C, Enzinger C, Korteweg T, Mancini L, Thompson A, De Stefano N, Montalban X, Hirsch J, Kappos L, Ropele S, Palace J, Barkhof F, Yousry T, Matthews PMet al., 2009, Functional connectivity changes of the motor network in patients with multiple sclerosis: a multi-centre fMRI study, 19th Meeting of the European-Neurological-Society, Publisher: DR DIETRICH STEINKOPFF VERLAG, Pages: S47-S48, ISSN: 0340-5354

CONFERENCE PAPER

Baranzini SE, Galwey NW, Wang J, Khankhanian P, Lindberg R, Pelletier D, Wu W, Uitdehaag BMJ, Kappos L, Polman CH, Matthews PM, Hauser SL, Gibson RA, Oksenberg JR, Barnes MRet al., 2009, Pathway and network-based analysis of genome-wide association studies in multiple sclerosis, HUMAN MOLECULAR GENETICS, Vol: 18, Pages: 2078-2090, ISSN: 0964-6906

JOURNAL ARTICLE

Filippini N, MacIntosh BJ, Hough MG, Goodwin GM, Frisoni GB, Smith SM, Matthews PM, Beckmann CF, Mackay CEet al., 2009, Distinct patterns of brain activity in young carriers of the APOE-epsilon 4 allele, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 106, Pages: 7209-7214, ISSN: 0027-8424

JOURNAL ARTICLE

Stagg CJ, Best JG, Stephenson MC, O'Shea J, Wylezinska M, Kincses ZT, Morris PG, Matthews PM, Johansen-Berg Het al., 2009, Polarity-Sensitive Modulation of Cortical Neurotransmitters by Transcranial Stimulation, JOURNAL OF NEUROSCIENCE, Vol: 29, Pages: 5202-5206, ISSN: 0270-6474

JOURNAL ARTICLE

Mancini L, Ciccarelli O, Manfredonia F, Thornton JS, Agosta F, Barkhof F, Beckmann C, De Stefano N, Enzinger C, Fazekas F, Filippi M, Gass A, Hirsch JG, Johansen-Berg H, Kappos L, Korteweg T, Manson SC, Marino S, Matthews PM, Montalban X, Palace J, Polman C, Rocca M, Ropele S, Rovira A, Wegner C, Friston KJ, Thompson A, Yousry Tet al., 2009, Short-term adaptation to a simple motor task: A physiological process preserved in multiple sclerosis, NEUROIMAGE, Vol: 45, Pages: 500-511, ISSN: 1053-8119

JOURNAL ARTICLE

Lin X, Song K, Lim N, Yuan X, Johnson T, Abderrahmani A, Vollenweider P, Stirnadel H, Sundseth SS, Lai E, Burns DK, Middleton LT, Roses AD, Matthews PM, Waeber G, Cardon L, Waterworth DM, Mooser Vet al., 2009, Risk prediction of prevalent diabetes in a Swiss population using a weighted genetic score-the CoLaus Study, DIABETOLOGIA, Vol: 52, Pages: 600-608, ISSN: 0012-186X

JOURNAL ARTICLE

This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.

Request URL: http://wlsprd.imperial.ac.uk:80/respub/WEB-INF/jsp/search-html.jsp Request URI: /respub/WEB-INF/jsp/search-html.jsp Query String: id=00501273&limit=30&person=true&page=8&respub-action=search.html