Imperial College London

Professor Paul M. Matthews

Faculty of MedicineDepartment of Brain Sciences

Edmond and Lily Safra Chair, Head of Department



+44 (0)20 7594 2855p.matthews




Ms Siobhan Dillon +44 (0)20 7594 2855




E502Burlington DanesHammersmith Campus






BibTex format

author = {Miller, KL and Alfaro-Almagro, F and Bangerter, NK and Thomas, DL and Yacoub, E and Xu, J and Bartsch, AJ and Jbabdi, S and Sotiropoulos, SN and Andersson, JL and Griffanti, L and Douaud, G and Okell, TW and Weale, P and Dragonu, I and Garratt, S and Hudson, S and Collins, R and Jenkinson, M and Matthews, PM and Smith, SM},
doi = {10.1038/nn.4393},
journal = {Nature Neuroscience},
pages = {1523--1536},
title = {Multimodal population brain imaging in the UK Biobank prospective epidemiological study},
url = {},
volume = {19},
year = {2016}

RIS format (EndNote, RefMan)

AB - Medical imaging has enormous potential for early disease prediction, but is impeded by the difficulty and expense of acquiring data sets before symptom onset. UK Biobank aims to address this problem directly by acquiring high-quality, consistently acquired imaging data from 100,000 predominantly healthy participants, with health outcomes being tracked over the coming decades. The brain imaging includes structural, diffusion and functional modalities. Along with body and cardiac imaging, genetics, lifestyle measures, biological phenotyping and health records, this imaging is expected to enable discovery of imaging markers of a broad range of diseases at their earliest stages, as well as provide unique insight into disease mechanisms. We describe UK Biobank brain imaging and present results derived from the first 5,000 participants' data release. Although this covers just 5% of the ultimate cohort, it has already yielded a rich range of associations between brain imaging and other measures collected by UK Biobank.
AU - Miller,KL
AU - Alfaro-Almagro,F
AU - Bangerter,NK
AU - Thomas,DL
AU - Yacoub,E
AU - Xu,J
AU - Bartsch,AJ
AU - Jbabdi,S
AU - Sotiropoulos,SN
AU - Andersson,JL
AU - Griffanti,L
AU - Douaud,G
AU - Okell,TW
AU - Weale,P
AU - Dragonu,I
AU - Garratt,S
AU - Hudson,S
AU - Collins,R
AU - Jenkinson,M
AU - Matthews,PM
AU - Smith,SM
DO - 10.1038/nn.4393
EP - 1536
PY - 2016///
SN - 1546-1726
SP - 1523
TI - Multimodal population brain imaging in the UK Biobank prospective epidemiological study
T2 - Nature Neuroscience
UR -
UR -
VL - 19
ER -