Publications
756 results found
Matthews PM, 2004, Commentary on “freud’s theory of mind and functional imaging experiments”, Neuropsychoanalysis, Vol: 6, Pages: 144-149, ISSN: 1529-4145
Matthews PM, Jezzard P, 2004, Functional magnetic resonance imaging, JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol: 75, Pages: 6-12, ISSN: 0022-3050
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- Citations: 129
Cifelli A, Arnold DL, Matthews PM, 2004, MRI Visualization of Multiple Sclerosis, Myelin Biology and Disorders, Pages: 763-790, ISBN: 9780124395107
This chapter outlines the basic principles of magnetic resonance imaging (MRI) and related techniques. MRI techniques define pathology on the basis of changes in biophysical parameters of tissue. With an understanding of these biophysical parameters, it can be appreciated that they have variably specific relations with pathological features as defined using traditional methods. This visualization of pathological changes in vivo has had a profound impact on the clinical management of patients with multiple sclerosis (MS), and on the understanding of the disease and its treatment. The chapter also reviews several contributions of MRI and related techniques to the understanding of multiple sclerosis (MS) and to pathology. MR and related techniques have been important particularly in emphasizing that much pathological change is subclinical, the diffuse nature of pathology, the prominence of gray matter involvement, and the role of neurodegeneration, even in the early stages of disease evolution. Together, these observations provide a remarkably comprehensive view of key features essential for understanding the way MS progresses. © 2004 Elsevier Inc. All rights reserved.
Matthews PM, 2004, Finding landmarks for understanding white matter stroke, STROKE, Vol: 35, Pages: 92-93, ISSN: 0039-2499
Matthews PM, Johansen-Berg H, Reddy H, 2004, Non-invasive mapping of brain functions and brain recovery: Applying lessons from cognitive neuroscience to neurorehabilitation, RESTORATIVE NEUROLOGY AND NEUROSCIENCE, Vol: 22, Pages: 245-260, ISSN: 0922-6028
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- Citations: 57
Smith SM, Jenkinson M, Woolrich MW, et al., 2004, Advances in functional and structural MR image analysis and implementation as FSL, NEUROIMAGE, Vol: 23, Pages: S208-S219, ISSN: 1053-8119
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- Citations: 9362
Devlin JT, Raley J, Tunbridge E, et al., 2003, Functional asymmetry for auditory processing in human primary auditory cortex, JOURNAL OF NEUROSCIENCE, Vol: 23, Pages: 11516-11522, ISSN: 0270-6474
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- Citations: 100
Bridge H, Clare S, Jezzard P, et al., 2003, A comparison of structurally and functionally defined human primary visual cortex, Journal of Vision, Vol: 3, ISSN: 1534-7362
Early visual areas can be defined using fMRI on the basis of their retinotopic organisation. Recently, very high-resolution images of the human brain in vivo have identified areas of myelination within the grey matter, corresponding to the striate cortex (Barbier et al. 2002; Clare et al. 2002). This myelination has traditionally been understood to correspond to the human primary visual cortex (V1). To test this correspondence, we compared the location of visually identified striate in high resolution images with the location of functionally defined V1. For imaging the myeloarchitecture, a magnetisation prepared 3D FLASH sequence was used as described in Clare et al. (2002). The resulting images had a resolution of 0.3×0.3×1.5 mm. Functional MRI was performed at a lower resolution of 3×3×1.5 mm using single shot EPI at the same 16 slice locations as the structural scan. Retinotopy data were collected using expanding ring and rotating wedge stimuli. The data were transformed onto a segmented (mrGray) and flattened (mrFlatMesh) T1-weighted scan (1×1×1mm). V1 was defined by locating the upper and lower field V1/V2 borders from the rotating wedge phase map. From the high-resolution myeloarchitecture images, striate cortex was conservatively determined as those regions where a stripe was identified within the grey matter. These observer drawn maps of striate cortex were then transformed into flattened space to allow comparison with the functional data. A good level of correspondence was found between the striate cortex determined in the structural MRI and V1 determined by fMRI. While the striate cortex was not identified as a continuous band, it is hoped that more striate will be revealed by using multiple slice orientations in the same subjects. In the future these very high-resolution structural images will offer the opportunity to combine the study of myeloarchitecture with functional architecture in the living human cortex.
Parry AMM, Scott RB, Palace J, et al., 2003, Potentially adaptive functional changes in cognitive processing for patients with multiple sclerosis and their acute modulation by rivastigmine, BRAIN, Vol: 126, Pages: 2750-2760, ISSN: 0006-8950
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- Citations: 124
Narain C, Scott SK, Wise RJS, et al., 2003, Defining a left-lateralized response specific to intelligible speech using fMRI, CEREBRAL CORTEX, Vol: 13, Pages: 1362-1368, ISSN: 1047-3211
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- Citations: 196
Johansen-Berg H, Dawes H, Guy C, et al., 2003, Correlation between motor improvements and altered fMRI activity after rehabilitative therapy. (vol 125, pg 2731, 2002), BRAIN, Vol: 126, Pages: 2569-2569, ISSN: 0006-8950
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- Citations: 2
Behrens TEJ, Woolrich MW, Jenkinson M, et al., 2003, Characterization and propagation of uncertainty in diffusion-weighted MR imaging, MAGNETIC RESONANCE IN MEDICINE, Vol: 50, Pages: 1077-1088, ISSN: 0740-3194
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- Citations: 2212
Wikström MA, Matthews P, Roberts D, et al., 2003, Parallel kinase cascades are involved in the induction of LTP at hippocampal CA1 synapses, NEUROPHARMACOLOGY, Vol: 45, Pages: 828-836, ISSN: 0028-3908
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- Citations: 40
Abu-Omar Y, Balacumaraswami L, Pigott DW, et al., 2003, Solid and gaseous cerebral microembolisation during off-pump, on-pump and open cardiac surgery, 76th Annual Scientific Session of the American-Heart-Association, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 549-549, ISSN: 0009-7322
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- Citations: 1
Abu-Omar Y, Matthews PM, Cifelli A, et al., 2003, Defining cerebral dysfunction related to microembolism during cardiac surgery with functional magnetic resonance imaging, 76th Annual Scientific Session of the American-Heart-Association, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 512-512, ISSN: 0009-7322
Parry A, Matthews PM, 2003, Roles for Imaging in Understanding the Pathophysiology, Clinical Evaluation, and Management of Patients with Mitochondrial Disease, Journal of Neuroimaging, Vol: 13, Pages: 293-302, ISSN: 1051-2284
Parry A, Matthews PM, 2003, Roles for imaging in understanding the pathophysiology, clinical evaluation, and management of patients with mitochondrial disease, JOURNAL OF NEUROIMAGING, Vol: 13, Pages: 293-302, ISSN: 1051-2284
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- Citations: 8
Bhagwagar Z, Wylezinska M, Taylor M, et al., 2003, Acute administration of a selective serotonin re-uptake inhibitor increases brain GABA concentrations, Summer Meeting of the British-Association-for-Psychopharmacology, Publisher: SAGE PUBLICATIONS LTD, Pages: A14-A14, ISSN: 0269-8811
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- Citations: 1
Völlm BA, de Araujo IET, Kringelbach ML, et al., 2003, Neural correlates of the subjective effects of i.v. amphetamine:: an fMRI study in healthy volunteers, Summer Meeting of the British-Association-for-Psychopharmacology, Publisher: SAGE PUBLICATIONS LTD, Pages: A73-A73, ISSN: 0269-8811
Cifelli AI, Wylezinska M, Jezzard P, et al., 2003, Thalamic neurodegeneration in relapsing: Remitting multiple sclerosis, Joint Congress of the Association-of-British-Neurologists/Neurological-Association-of-South-Africa, Publisher: BRITISH MED JOURNAL PUBL GROUP, Pages: 1177-1177, ISSN: 0022-3050
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- Citations: 1
Wegner C, Matthews PM, 2003, A new view of the cortex, new insights into multiple sclerosis, BRAIN, Vol: 126, Pages: 1719-1721, ISSN: 0006-8950
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- Citations: 11
Palace J, Parry A, Clare S, et al., 2003, T1 changes detect the progression of pathology in the white matter and cortex of MS patients, Joint Congress of the Association-of-British-Neurologists/Neurological-Association-of-South-Africa, Publisher: BRITISH MED JOURNAL PUBL GROUP, Pages: 1179-1179, ISSN: 0022-3050
Parry A, Clare S, Jenkinson M, et al., 2003, MRI Brain T1 Relaxation Time Changes in MS Patients Increase Over Time in Both the White Matter and the Cortex, Journal of Neuroimaging, Vol: 13, Pages: 234-239, ISSN: 1051-2284
Behrens TEJ, Johansen-Berg H, Woolrich MW, et al., 2003, Non-invasive mapping of connections between human thalamus and cortex using diffusion imaging, NATURE NEUROSCIENCE, Vol: 6, Pages: 750-757, ISSN: 1097-6256
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- Citations: 1812
Parry A, Clare S, Jenkinson M, et al., 2003, MRI brain T1 relaxation time changes in MS patients increase over time in both the white matter and the cortex, JOURNAL OF NEUROIMAGING, Vol: 13, Pages: 234-239, ISSN: 1051-2284
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- Citations: 36
Wylezinska M, Cifelli A, Jezzard P, et al., 2003, Thalamic neurodegeneration in relapsing-remitting multiple sclerosis, NEUROLOGY, Vol: 60, Pages: 1949-1954, ISSN: 0028-3878
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- Citations: 146
Austin VC, Blamire AM, Grieve SM, et al., 2003, Differences in the BOLD fMRI response to direct and indirect cortical stimulation in the rat, MAGNETIC RESONANCE IN MEDICINE, Vol: 49, Pages: 838-847, ISSN: 0740-3194
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- Citations: 39
Vollm BA, Araujo I, Kringelbach M, et al., 2003, Neural correlates of the subjective effects of IV amphetamine: An fMRI study in healthy volunteers, 58th Annual Convention and Scientific Program of the Society-of-Biological-Psychiatry, Publisher: ELSEVIER SCIENCE INC, Pages: 216S-216S, ISSN: 0006-3223
De Stefano N, Matthews PM, Filippi M, et al., 2003, Evidence of early cortical atrophy in MS relevance to white matter changes and disability, 54th Annual Meeting of the American-Academy-of-Neurology, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 1157-1162, ISSN: 0028-3878
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- Citations: 393
Matthews PM, Adcock J, Chen Y, et al., 2003, Towards understanding language organisation in the brain using fMRI, HUMAN BRAIN MAPPING, Vol: 18, Pages: 239-247, ISSN: 1065-9471
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- Citations: 35
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