Summary
Phil is the GSK/Asthma Lung UK Chair of Respiratory Research and Consultant in Interstitial lung disease at the Royal Brompton Hospital, where he is the director of the NIHR Clinical Research Facility.
Phil qualified from Guy's, King's and St Thomas' School of Medicine in 2004, where he completed an intercalated BSc. in Molecular Genetics. He undertook his SHO training at Guy’s and St Thomas’ and upon completion of the MRCP attained an NIHR Academic Clinical Fellow position in Respiratory medicine at Imperial College. He spent the next two years training at St Mary’s Hospital and working with Professors Cookson, Moffatt and Johnston studying the respiratory microbiome in COPD.
An Asmarley training fellowship allowed him to undertake a PhD examining the host response to the respiratory microbiome in Idiopathic Pulmonary Fibrosis as part of the Prospective Study of Fibrosis In the Lung Endpoints (PROFILE) study with Professor Maher.
Having completed his clinical training in Respiratory and Critical Care Medicine he returned to Imperial joining the Fibrosis Research Group as a Senior Clinical Lecturer. He was awarded the Action for Pulmonary Fibrosis Mike Bray Fellowship which enabled him to establish his research group studying the interaction between the respiratory tract microbiota and innate immunity in pulmonary fibrosis.
Publications
Journals
Wu Z, Spencer LG, Banya W, et al., 2024, Morphine for treatment of cough in idiopathic pulmonary fibrosis (PACIFY COUGH): a prospective, multicentre, randomised, double-blind, placebo-controlled, two-way crossover trial, The Lancet Respiratory Medicine, Vol:12, ISSN:2213-2600, Pages:273-280
Joulia RPG, Puttur F, Stölting H, et al., 2024, Mast cell activation disrupts interactions between endothelial cells and pericytes during early life allergic asthma, Journal of Clinical Investigation, ISSN:0021-9738
Thillai M, Oldham JM, Ruggiero A, et al., 2024, Deep Learning-based Segmentation of CT Scans Predicts Disease Progression and Mortality in IPF., Am J Respir Crit Care Med
Wu Z, Smith DJF, Yazbeck L, et al., 2024, Cough Severity Visual Analogue Scale Assesses Cough Burden and Predicts Survival in Idiopathic Pulmonary Fibrosis., Am J Respir Crit Care Med
Maher TM, Tudor VA, Saunders P, et al., 2024, Rituximab compared to intravenous cyclophosphamide in adults with connective tissue disease-associated interstitial lung disease: the RECITAL RCT, Efficacy and Mechanism Evaluation, ISSN:2050-4365, Pages:1-68