Imperial College London
Portrait Picture

ProfessorPhilipMolyneaux

Faculty of Medicine, National Heart & Lung Institute

Professor of Interstitial Lung Disease
 
 
 
//

Contact

 

p.molyneaux

 
 
//

Location

 

Sir Alexander Fleming BuildingSouth Kensington Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Invernizzi:2019:10.1183/16000617.0045-2019,
author = {Invernizzi, R and Molyneaux, PL},
doi = {10.1183/16000617.0045-2019},
journal = {European Respiratory Review},
title = {The contribution of infection and the respiratory microbiome in acute exacerbations of idiopathic pulmonary fibrosis},
url = {http://dx.doi.org/10.1183/16000617.0045-2019},
volume = {28},
year = {2019}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Idiopathic pulmonary fibrosis (IPF) arises in genetically susceptible individuals as a result of an aberrant wound-healing response following repetitive alveolar injury. The clinical course of the disease remains both variable and unpredictable with periods of more rapid decline, termed acute exacerbation of IPF (AE-IPF), often punctuating the disease trajectory. Exacerbations carry a significant morbidity and mortality, and their exact pathogenesis remains unclear. Given the emerging evidence that disruption and alteration in the lung microbiome plays a role in the pathogenesis and progression of IPF, this review discusses the current knowledge of the contribution of infection and the respiratory microbiome to AE-IPF.
AU  - Invernizzi,R
AU  - Molyneaux,PL
DO  - 10.1183/16000617.0045-2019
PY  - 2019///
SN  - 0905-9180
TI  - The contribution of infection and the respiratory microbiome in acute exacerbations of idiopathic pulmonary fibrosis
T2  - European Respiratory Review
UR  - http://dx.doi.org/10.1183/16000617.0045-2019
UR  - https://www.ncbi.nlm.nih.gov/pubmed/31285290
UR  - http://hdl.handle.net/10044/1/72274
VL  - 28
ER  -
Download