Imperial College London
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ProfessorPhilipMolyneaux

Faculty of Medicine, National Heart & Lung Institute

Professor of Interstitial Lung Disease
 
 
 
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Contact

 

p.molyneaux

 
 
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Location

 

Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Carney:2020:10.1165/rcmb.2019-0273TR,
author = {Carney, SM and Clemente, JC and Cox, MJ and Dickson, RP and Huang, YJ and Kitsios, GD and Kloepfer, KM and Leung, JM and LeVan, TD and Molyneaux, PL and Moore, BB and O'Dwyer, DN and Segal, LN and Garantziotis, S and ATS, Allergy and Immunology, and Inflammation Assembly Working Group on Microbiome in Lung Disease},
doi = {10.1165/rcmb.2019-0273TR},
journal = {American Journal of Respiratory Cell and Molecular Biology},
pages = {283--299},
title = {Methods in lung microbiome research.},
url = {http://dx.doi.org/10.1165/rcmb.2019-0273TR},
volume = {62},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The lung microbiome is associated with host immune response and health outcomes in experimental models and patient cohorts. Lung microbiome research is increasing in volume and scope; however, there are no established guidelines for study design, conduct and reporting of lung microbiome studies. Standardized approaches to yield reliable and reproducible data that can be synthesized across studies, will ultimately improve the scientific rigor and impact of published work and greatly benefit microbiome research. In this review, we identify and address several key elements of microbiome research: conceptual modeling and hypothesis framing, study design, experimental methodology and pitfalls, data analysis and reporting considerations. Finally, we explore possible future directions and research opportunities. Our goal is to aid investigators who are interested in this burgeoning research area and will hopefully provide the foundation for formulating consensus approaches in lung microbiome research.
AU  - Carney,SM
AU  - Clemente,JC
AU  - Cox,MJ
AU  - Dickson,RP
AU  - Huang,YJ
AU  - Kitsios,GD
AU  - Kloepfer,KM
AU  - Leung,JM
AU  - LeVan,TD
AU  - Molyneaux,PL
AU  - Moore,BB
AU  - O'Dwyer,DN
AU  - Segal,LN
AU  - Garantziotis,S
AU  - ATS,Allergy
AU  - Immunology,and Inflammation Assembly Working Group on Microbiome in Lung Disease
DO  - 10.1165/rcmb.2019-0273TR
EP  - 299
PY  - 2020///
SN  - 1044-1549
SP  - 283
TI  - Methods in lung microbiome research.
T2  - American Journal of Respiratory Cell and Molecular Biology
UR  - http://dx.doi.org/10.1165/rcmb.2019-0273TR
UR  - https://www.ncbi.nlm.nih.gov/pubmed/31661299
UR  - https://www.atsjournals.org/doi/10.1165/rcmb.2019-0273TR
UR  - http://hdl.handle.net/10044/1/74655
VL  - 62
ER  -
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