Imperial College London

ProfessorPaoloMuraro

Faculty of MedicineDepartment of Brain Sciences

Professor of Neurology - Neuroimmunology and Immunotherapy
 
 
 
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Contact

 

p.muraro Website

 
 
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Assistant

 

Mrs Gearoidin Beazley +44 (0)20 7594 7047

 
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Location

 

E415Burlington DanesHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Arrambide:2020:10.1177/1352458520924595,
author = {Arrambide, G and Iacobaeus, E and Amato, MP and Derfuss, T and Vukusic, S and Hemmer, B and Brundin, L and Tintore, M and 2018, ECTRIMS Focused Workshop Group},
doi = {10.1177/1352458520924595},
journal = {Multiple Sclerosis Journal},
pages = {1045--1063},
title = {Aggressive multiple sclerosis (2): Treatment.},
url = {http://dx.doi.org/10.1177/1352458520924595},
volume = {26},
year = {2020}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - The natural history of multiple sclerosis (MS) is highly heterogeneous. A subgroup of patients has what might be termed aggressive MS. These patients may have frequent, severe relapses with incomplete recovery and are at risk of developing greater and permanent disability at the earlier stages of the disease. Their therapeutic window of opportunity may be narrow, and while it is generally considered that they will benefit from starting early with a highly efficacious treatment, a unified definition of aggressive MS does not exist and data on its treatment are largely lacking. Based on discussions at an international focused workshop sponsored by the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), we review our current knowledge about treatment of individuals with aggressive MS. We analyse the available evidence, identify gaps in knowledge and suggest future research needed to fill those gaps. A companion paper details the difficulties in developing a consensus about what defines aggressive MS.
AU - Arrambide,G
AU - Iacobaeus,E
AU - Amato,MP
AU - Derfuss,T
AU - Vukusic,S
AU - Hemmer,B
AU - Brundin,L
AU - Tintore,M
AU - 2018,ECTRIMS Focused Workshop Group
DO - 10.1177/1352458520924595
EP - 1063
PY - 2020///
SN - 1352-4585
SP - 1045
TI - Aggressive multiple sclerosis (2): Treatment.
T2 - Multiple Sclerosis Journal
UR - http://dx.doi.org/10.1177/1352458520924595
UR - https://www.ncbi.nlm.nih.gov/pubmed/32530366
UR - https://journals.sagepub.com/doi/10.1177/1352458520924595
UR - http://hdl.handle.net/10044/1/90753
VL - 26
ER -