Imperial College London
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Peter Openshaw - Professor of Experimental Medicine

Faculty of Medicine, National Heart & Lung Institute

Proconsul, Professor of Experimental Medicine
 
 
 
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Contact

 

+44 (0)20 7594 3854p.openshaw Website CV

 
 
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Assistant

 

Ms Gale Lewis +44 (0)20 7594 0944

 
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Location

 

353Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Schwarze:2018:10.1111/all.13333,
author = {Schwarze, J and Openshaw, P and Jha, A and Del, Giacco SR and Firinu, D and Tsilochristou, O and Roberts, G and Selby, A and Akdis, C and Agache, I and Custovic, A and Heffler, E and Pinna, G and Khaitov, M and Nikonova, A and Papadopoulos, N and Akhlaq, A and Nurmatov, U and Renz, H and Sheikh, A and Skevaki, C},
doi = {10.1111/all.13333},
journal = {Allergy},
pages = {1151--1181},
title = {Influenza burden, prevention and treatment in asthma - a scoping review by the EAACI Influenza in Asthma Task Force},
url = {http://dx.doi.org/10.1111/all.13333},
volume = {73},
year = {2018}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - To address uncertainties in the prevention and management of influenza in people with asthma, we performed a scoping review of the published literature on influenza burden; current vaccine recommendations; vaccination coverage; immunogenicity, efficacy, effectiveness and safety of influenza vaccines; and the benefits of antiviral drugs in people with asthma. We found significant variation in the reported rates of influenza detection in individuals with acute asthma exacerbations making it unclear to what degree influenza causes exacerbations of underlying asthma. The strongest evidence of an association was seen in studies of children. Countries in the European Union currently recommend influenza vaccination of adults with asthma; however, coverage varied between regions. Coverage was lower among children with asthma. Limited data suggest that good seroprotection and seroconversion can be achieved in both children and adults with asthma and that vaccination confers a degree of protection against influenza illness and asthma related morbidity to children with asthma. There were insufficient data to determine efficacy in adults. Overall, influenza vaccines appeared to be safe for people with asthma. We identify knowledge gaps and make recommendations on future research needs in relation to influenza in patients with asthma. This article is protected by copyright. All rights reserved.
AU  - Schwarze,J
AU  - Openshaw,P
AU  - Jha,A
AU  - Del,Giacco SR
AU  - Firinu,D
AU  - Tsilochristou,O
AU  - Roberts,G
AU  - Selby,A
AU  - Akdis,C
AU  - Agache,I
AU  - Custovic,A
AU  - Heffler,E
AU  - Pinna,G
AU  - Khaitov,M
AU  - Nikonova,A
AU  - Papadopoulos,N
AU  - Akhlaq,A
AU  - Nurmatov,U
AU  - Renz,H
AU  - Sheikh,A
AU  - Skevaki,C
DO  - 10.1111/all.13333
EP  - 1181
PY  - 2018///
SN  - 0105-4538
SP  - 1151
TI  - Influenza burden, prevention and treatment in asthma - a scoping review by the EAACI Influenza in Asthma Task Force
T2  - Allergy
UR  - http://dx.doi.org/10.1111/all.13333
UR  - https://www.ncbi.nlm.nih.gov/pubmed/29105786
UR  - http://hdl.handle.net/10044/1/54810
VL  - 73
ER  -
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