Summary
Poh-Choo is a visiting researcher at the Biopolymer Mass Spectrometry group under Professor Anne Dell and Dr Stuart Haslam doing research on glycobiology.
BIOGRAPHY
When Poh-Choo was a full-time Post-doctorate Research Associate at Department of Life Sciences, she worked with Professor Anne Dell and Dr Stuart Haslam. During her time as a postdoc, she did research, teaching, and training on structural glycobiology (glycomics, glycoproteomics, and proteomics) using mass spectrometry to study cell-to-cell recognition in reproduction and immune systems in order to understand how structural sugars on the cell surfaces are involved in human/animal health and disease. She had been a regular Outreach Scientist to communicate her research to the public at events organised by the Royal Society, BBSRC, Wellcome Trust and London International Youth Forum. In addition, she has been a mass spectrometer instrument manager and a health and safety officer for the Dell/Haslam Lab. Poh-Choo is also a qualified first aider.
As a postdoc, she also worked closely with Department of Life Sciences Postdoc Committee and the Postdoc and Fellows Development Centre. As a postdoc representative for the department, she helped organise postdoc symposiums, career development training workshops, and networking events. Also, she facilitated communication between postdocs and College upper-level management to influence and enable strategic decision-making for various College policies.
Poh-Choo completed her Imperial College funded Ph.D. in Structural Glycobiology from the Imperial College, and her research was on reproductive glycobiology. Using mass spectrometry, she carried out glycomic studies to elucidate glycomes of several systems (human and mammals) in reproductive biology.
She also holds a B.Sc. (First Class Honours) in Genetics and Molecular Biology from University of Malaya. Her final year research was on isolation and characterisation of Vibriophages from the environment to search for drug alternatives to antibiotics for the treatment and prevention of pathogenic bacteria infections (supervised by Professor Chong-Lek Koh and Dr Kok-Gan Chan).
Fun fact: she enjoys running/cycling around the parks, baking for friends and absolutely loves jazz.
Selected Publications
Journal Articles
Pham ND, Pang P-C, Krishnamurthy S, et al., 2017, Effects of altered sialic acid biosynthesis on N-linked glycan branching and cell surface interactions, Journal of Biological Chemistry, Vol:292, ISSN:0021-9258, Pages:9637-9651
Lété C, Markine-Goriaynoff N, Machiels B, et al., 2016, Bovine Herpesvirus 4 Modulates Its β-1,6-N-Acetylglucosaminyltransferase Activity through Alternative Splicing, Journal of Virology, Vol:90, Pages:2039-2051
Pang P-C, Haslam SM, Dell A, et al., 2016, The human fetoembryonic defense system hypothesis: Twenty years on, Molecular Aspects of Medicine, Vol:51, ISSN:0098-2997, Pages:71-88
Chen Q, Pang P-C, Cohen ME, et al., 2016, Evidence for Differential Glycosylation of Trophoblast Cell Types, Molecular & Cellular Proteomics, Vol:15, Pages:1857-1866
Stansell A, 2015, Gp120 on HIV-1 Virions Lacks O-Linked Carbohydrate, Plos One, Vol:10, Pages:1-15
Nataraj A, 2015, MKAN27435 Is Required for the Biosynthesis of Higher Subclasses of Lipooligosaccharides in Mycobacterium kansasii, PLOS One, Vol:10, ISSN:1932-6203
Chen Q, Müller JS, Pang P-C, et al., 2015, Global N-linked Glycosylation is Not Significantly Impaired in Myoblasts in Congenital Myasthenic Syndromes Caused by Defective Glutamine-Fructose-6-Phosphate Transaminase 1 (GFPT1), Biomolecules, Vol:5, ISSN:2218-273X, Pages:2758-2781
Pang P, Chiu PCN, Lee C, et al., 2011, Human Sperm Binding Is Mediated by the Sialyl-Lewisx Oligosaccharide on the Zona Pellucida, Science, Vol:333, Pages:1761-1764
Pang P, Tissot B, Drobnis EZ, et al., 2007, Expression of Bisecting Type and Lewisx/Lewisy Terminated N-Glycans on Human Sperm, Journal of Biological Chemistry, Vol:282, Pages:36593-36602