Imperial College London
Alternate

DrPeterPetrov

Faculty of Engineering, Department of Materials

Principal Research Scientist
 
 
 
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Contact

 

+44 (0)20 7594 8156p.petrov

 
 
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Location

 

2.03DRoyal School of MinesSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Ramadan:2021:10.1021/acsami.0c18293,
author = {Ramadan, S and Lobo, R and Zhang, Y and Xu, L and Shaforost, O and Tsang, DKH and Feng, J and Yin, T and Qiao, M and Rajeshirke, A and Jiao, LR and Petrov, PK and Dunlop, IE and Titirici, M-M and Klein, N},
doi = {10.1021/acsami.0c18293},
journal = {ACS Applied Materials and Interfaces},
pages = {7854--7864},
title = {Carbon-dot-enhanced graphene field-effect transistors for uitrasensitive detection of exosomes},
url = {http://dx.doi.org/10.1021/acsami.0c18293},
volume = {13},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Graphene field-effect transistors (GFETs) are suitable building blocks for high-performance electrical biosensors, because graphene inherently exhibits a strong response to charged biomolecules on its surface. However, achieving ultralow limit-of-detection (LoD) is limited by sensor response time and screening effect. Herein, we demonstrate that the detection limit of GFET biosensors can be improved significantly by decorating the uncovered graphene sensor area with carbon dots (CDs). The developed CDs-GFET biosensors used for exosome detection exhibited higher sensitivity, faster response, and three orders of magnitude improvements in the LoD compared with nondecorated GFET biosensors. A LoD down to 100 particles/μL was achieved with CDs-GFET sensor for exosome detection with the capability for further improvements. The results were further supported by atomic force microscopy (AFM) and fluorescent microscopy measurements. The high-performance CDs-GFET biosensors will aid the development of an ultrahigh sensitivity biosensing platform based on graphene for rapid and early diagnosis of diseases.
AU  - Ramadan,S
AU  - Lobo,R
AU  - Zhang,Y
AU  - Xu,L
AU  - Shaforost,O
AU  - Tsang,DKH
AU  - Feng,J
AU  - Yin,T
AU  - Qiao,M
AU  - Rajeshirke,A
AU  - Jiao,LR
AU  - Petrov,PK
AU  - Dunlop,IE
AU  - Titirici,M-M
AU  - Klein,N
DO  - 10.1021/acsami.0c18293
EP  - 7864
PY  - 2021///
SN  - 1944-8244
SP  - 7854
TI  - Carbon-dot-enhanced graphene field-effect transistors for uitrasensitive detection of exosomes
T2  - ACS Applied Materials and Interfaces
UR  - http://dx.doi.org/10.1021/acsami.0c18293
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000623228500003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://pubs.acs.org/doi/10.1021/acsami.0c18293
UR  - http://hdl.handle.net/10044/1/87368
VL  - 13
ER  -
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