Publications
296 results found
Attaran S, Punjabi PP, Anderson J, 2012, Postoperative Atrial Fibrillation: Year 2011 Review of Predictive and Preventative Factors of Atrial Fibrillation Post Cardiac Surgery., J Atr Fibrillation, Vol: 5, ISSN: 1941-6911
Background: Post cardiac surgery atrial fibrillation is common after cardiac surgery. Despite the advances in medical and surgical treatment, its incidence remains high and unchanged for decades. The aim of this review was to summarize studies published in 2011 on identifying factors, prevention strategies, treatment and effect of post operative atrial fibrillation (POAF) on the outcome after cardiac surgery. Methods: A review was performed on Medline, Embase and Chocrane on all of the English-language, peer-reviewed published clinical studies on POAF; studies investigating the mechanism of developing POAF, prevention, treatment and outcome were all included and analyzed. Case reports, studies on persistent/preoperative atrial fibrillation (AF), POAF after cardiac transplant, congenital cases and nonclinical studies were all excluded. We have also valuated these studies based on the type of the study, their originality, impact factor of the journal and their limitations. Results: Overall 62 studies were reviewed and analyzed; 26 on POAF predictive factors, 31 on preventative strategies and 6 on the outcome of POAF. Of these studies only two were original and the remaining were either performed in AF in general population (n=10) or had been studied and reported several times before in cardiac surgery (n=50). The average impact factor of the journals that POAF was published in was only 2.8 ranging between 0.5 and 14.5. Conclusion: Post cardiac surgery atrial fibrillation is a multi-factorial and complex condition. Cardiac surgery may be a risk factor for developing POAF in patients already susceptible to this condition and may not be a complication of cardiac surgery. Future studies should mainly focus on histological changes in the conductive tissue of atrium and related treatment strategies rather than predictive factors of POAF and more funding should be made available to study this condition from new and entirely different perspectives.
Zakkar M, Punjabi PP, 2012, Myocardial preservation techniques for mini-bypass, MINIMIZED CARDIOPULMONARY BYPASS TECHNIQUES AND TECHNOLOGIES, Pages: 141-153
Grapsa J, Dawson D, Jakaj G, et al., 2011, Strain Rate of Mitral Papillary Muscles: a New Imaging Prognostic Tool for Mitral Valve Repair, CIRCULATION, Vol: 124, ISSN: 0009-7322
Grapsa J, Jakaj G, Dawson D, et al., 2011, Longitudinal Strain of Mitral Papillary Muscles: Correlation with Mitral Regurgitation, CIRCULATION, Vol: 124, ISSN: 0009-7322
Punjabi PP, 2011, Perfusion - What is in a name?, PERFUSION-UK, Vol: 26, Pages: 457-458, ISSN: 0267-6591
Nawaz MA, Patni R, Chan KMJ, et al., 2011, Hyperinflation of lungs during redo-sternotomy, a safer technique, Heart Lung and Circulation, Vol: 20, Pages: 722-723
Harling L, Punjabi PP, Athanasiou T, 2011, Miniaturized extracorporeal circulation vs. off-pump coronary artery bypass grafting: what the evidence shows?, PERFUSION-UK, Vol: 26, Pages: 40-47, ISSN: 0267-6591
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- Citations: 12
Punjabi PP, 2011, "Silver Lining", PERFUSION-UK, Vol: 26, Pages: 5-5, ISSN: 0267-6591
Pandis D, Grapsa J, Athanasiou T, et al., 2011, Left ventricular remodeling and mitral valve surgery: Prospective study with real-time 3-dimensionale chocardiography and speckle tracking, JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, Vol: 142, Pages: 641-649, ISSN: 0022-5223
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- Citations: 24
Jarral OA, Jarral RA, Chan KMJ, et al., 2011, Use of a purse string suture in proximal coronary anastomosis to reduce size mismatch between conduit and aortotomy, Annals of the Royal College of Surgeons of England, Vol: 93, Pages: 415-416
Grapsa J, Dawson D, Athanasiou T, et al., 2011, Right ventricular remodelling post mitral valve surgery: study with real time 3D echocardiography, EUROPEAN HEART JOURNAL, Vol: 32, Pages: 443-443, ISSN: 0195-668X
Punjabi PP, 2011, Changing Constantly and Constant Change, PERFUSION-UK, Vol: 26, Pages: 261-261, ISSN: 0267-6591
Jarral OA, Jarral RA, Chan KMJ, et al., 2011, Use of a purse string suture in proximal coronary anastomosis to reduce size mismatch between conduit and aortotomy, ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND, Vol: 93, Pages: 415-416, ISSN: 0035-8843
Facer P, Punjabi PP, Abrari A, et al., 2011, Localisation of SCN10A Gene Product Na<sub>v</sub>1.8 and Novel Pain-Related Ion Channels in Human Heart, INTERNATIONAL HEART JOURNAL, Vol: 52, Pages: 146-152, ISSN: 1349-2365
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- Citations: 52
Nawaz MA, Curry P, Patni R, et al., 2011, An Audit of a Steriod Withdrawal Regimen in Cardiac Transplantation Patients, TRANSPLANTATION PROCEEDINGS, Vol: 43, Pages: 623-628, ISSN: 0041-1345
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- Citations: 2
Punjabi PP, 2011, Challenging the Conventional Wisdom, PERFUSION-UK, Vol: 26, Pages: 77-77, ISSN: 0267-6591
Zakkar M, Luong LA, Chaudhury H, et al., 2011, Dexamethasone Arterializes Venous Endothelial Cells by Inducing Mitogen-Activated Protein Kinase Phosphatase-1 A Novel Antiinflammatory Treatment for Vein Grafts?, CIRCULATION, Vol: 123, Pages: 524-U141, ISSN: 0009-7322
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- Citations: 27
Murphy MO, Rao C, Punjabi PP, et al., 2011, In patients undergoing mitral surgery for ischaemic mitral regurgitation is it preferable to repair or replace the mitral valve?, INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY, Vol: 12, Pages: 218-227, ISSN: 1569-9293
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- Citations: 10
Moscarelli M, Punjabi PP, 2011, Thoracotomy, Surgery, Vol: 29, Pages: 242-243, ISSN: 0263-9319
Thoracotomy is a surgical incision into the chest. It is performed to gain access to the thoracic organs. Several thoracotomy approaches are described in the literature, and the correct choice of approach will determine the exposure of the operative field and the success of the operation. The best approach must be balanced between the least aggressive and the safest exposure. Current approaches are reviewed here. © 2011 Elsevier Ltd. All rights reserved.
Facer P, Punjabi PP, Abrari A, et al., 2011, Localisation of SCN10A gene product Na(v)1.8 and novel pain-related ion channels in human heart., Int Heart J, Vol: 52, Pages: 146-152
We have shown that the gene SCN10A encoding the sodium channel Na(v)1.8 is a susceptibility factor for heart block and serious ventricular arrhythmia. Since Na(v)1.8 is known to be present in nerve fibres that mediate pain, it may be related to both cardiac pain and dysrhythmia. The localisation of Na(v)1.8 and other key nociceptive ion channels, including Na(v)1.7, Na(v)1.9, capsaicin receptor TRPV1, and purinergic receptor P2X(3), have not been reported in human heart. The aim of this study was to determine the distribution of Na(v)1.8, related sodium and other sensory channels in human cardiac tissue, and correlate their density with sympathetic nerves, regenerating nerves (GAP-43), and vascularity. Human heart atrial appendage tissues (n = 13) were collected during surgery for valve disease. Tissues were investigated by immunohistology using specific antibodies to Na(v)1.8 and other markers. Na(v)1.8 immunoreactivity was detected in nerve fibres and fascicles in the myocardium, often closely associated with small capillaries. Na(v)1.8 nerve fibres per mm(2) correlated significantly with vascular markers. Na(v)1.8-immunoreactivity was present also in cardiomyocytes with a similar distribution pattern to that seen with connexins, the specialised gap junction proteins of myocardial intercalated discs. Na(v)1.5-immunoreactivity was detected in cardiomyocytes but not in nerve fibres. Na(v)1.7, Na(v)1.9, TRPV1, P2X(3)/P2X(2), and GAP43 positive nerve fibres were relatively sparse, whereas sympathetic innervation and connexin43 were abundant. We conclude that sodium channel Na(v)1.8 is present in sensory nerves and cardiomyocytes of human heart. Na(v)1.8 and other pain channels provide new targets for the understanding and treatment of cardiac pain and dysrhythmia.
Punjabi PP, 2010, The Past, The Present and The Future, PERFUSION-UK, Vol: 25, Pages: 361-361, ISSN: 0267-6591
Stoica S, Goldsmith K, Demiris N, et al., 2010, Microsimulation and clinical outcomes analysis support a lower age threshold for use of biological valves, HEART, Vol: 96, Pages: 1730-1736, ISSN: 1355-6037
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- Citations: 27
Grapsa J, Dawson D, Nihoyannopoulos P, et al., 2010, Surgical management of valvular heart disease, Medicine, Vol: 38, Pages: 545-549, ISSN: 1357-3039
The term 'valvular heart disease' incorporates a wide range of conditions. The gold-standard diagnostic techniques, the natural history, and the interventional, as well as surgical, techniques which are available for treatment should be known by the clinician. The surgical management of valvular heart disease involves a series of operations and techniques. The aim of this review is to describe valvular pathology and the available surgical techniques. © 2010 Elsevier Ltd. All rights reserved.
Grapsa J, Gibbs JSR, Athanasiou T, et al., 2010, Morphologic and functional remodeling of the right ventricle in pulmonary hypertension: the role of real time three dimensional echocardiography, ESC Congress, Publisher: OXFORD UNIV PRESS, Pages: 751-752, ISSN: 0195-668X
Pandis D, Grapsa J, Stefanou D, et al., 2010, The return of mitral regurgitation: could we have seen it coming (following surgery)?, ESC Congress, Publisher: OXFORD UNIV PRESS, Pages: 473-473, ISSN: 0195-668X
Punjabi PP, 2010, Scientific Expertise, PERFUSION-UK, Vol: 25, Pages: 281-281, ISSN: 0267-6591
Jarral OA, Jarral RA, Khan MT, et al., 2010, A Simple Technique to Control Anastomotic Suture Line Bleeding, ANNALS OF THORACIC SURGERY, Vol: 90, Pages: 1030-1031, ISSN: 0003-4975
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- Citations: 1
Zakkar M, Punjabi P, Anderson J, et al., 2010, Dexamethasone arterializes venous endothelial cells by inducing MAP Kinase phosphatase-1 (MKP-1). A novel anti-inflammatory treatment for vein grafts., 45th Congress of the European-Society-for-Surgical-Research, Publisher: JOHN WILEY & SONS LTD, Pages: S12-S13, ISSN: 0007-1323
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- Citations: 1
Dubrey SW, Kohli SK, Grocott-Mason R, et al., 2010, Rheumatic mitral valve disease in pregnancy, BRITISH JOURNAL OF HOSPITAL MEDICINE, Vol: 71, Pages: 294-294, ISSN: 1750-8460
Punjabi PP, 2010, Responsibilities of the Editor, PERFUSION-UK, Vol: 25, Pages: 113-114, ISSN: 0267-6591
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