Mr Prakash P Punjabi

Thurlerdar S, Puntmann VO, Punjabi P, Bogle Ret al., 2008, Rapid detection of acute renal dysfunction by serum and urinary neutrophil gelatinase-associated lipocalin (NGAL) after cardiopulmonary bypass., World Congress in Cardiology

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Cook SA, Khan MT, Mongillo M, Leccisotti L, Strickland N, Matsui T, Rosenzweig A, Punjabi P, Camici Pet al., 2007, Paradoxical activation of myocardial insulin signaling in type 2 diabetes mellitus and left ventricular dysfunction, Publisher: OXFORD UNIV PRESS, Pages: 551-551, ISSN: 0195-668X

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Cook S, Khan T, Mongillo M, Leccisotti L, Strickland N, Rosenzweig A, Punjabi P, Camici Pet al., 2007, Common abnormalities of insulin action in patients with diabetes and heart failure, Annual Scientific Conference of the British-Cardiovascular-Society, Publisher: B M J PUBLISHING GROUP, Pages: A40-A40, ISSN: 1355-6037

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Lu H, Punjabi P, Rahman F, Camici P, Aitman T, Cook Set al., 2007, Characterisation of microRNAs in the human heart, Annual Scientific Conference of the British-Cardiovascular-Society, Publisher: B M J PUBLISHING GROUP, Pages: A77-A77, ISSN: 1355-6037

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Reddy NS, Punjabi P, 2007, Heart valve surgery, Surgery, Vol: 25, Pages: 220-223, ISSN: 0263-9319

People with valvular heart disease are living longer, with less morbidity, than ever before; advances in surgical techniques and better understanding of the timing of surgery account for this increased survival. In general, patients with stenotic valvular lesions can be monitored clinically until symptoms appear. Patients with regurgitant valvular lesions require careful echocardiographic monitoring for left ventricular function and may require surgery even if symptoms are absent. Aside from antibiotic prophylaxis, very little medical therapy is available for patients with valvular heart disease. Surgery is the treatment for most symptomatic lesions. © 2007 Elsevier Ltd. All rights reserved.

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Punjabi P P, 2007, Novel Aortic Canula

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Tuladhar SM, Punjabi PP, 2006, Surgical reconstruction of the mitral valve, HEART, Vol: 92, Pages: 1373-1377, ISSN: 1355-6037

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• Citations: 13

Ajzan A, Modine T, Punjabi P, Ganeshalingam K, Philips G, Gourlay Tet al., 2006, Quantification of fat mobilization in patients undergoing coronary artery revascularization using off-pump and on-pump techniques., J Extra Corpor Technol, Vol: 38, Pages: 116-121, ISSN: 0022-1058

Fat mobilization during cardiopulmonary bypass (CPB) is a recognized risk of the procedure. Intravascular mobilization of fat emboli subsequent to CPB has been implicated in some of its recognized pathophysiologies, particularly with regard to cerebral embolic injury. The aim of this study was to investigate whether fat mobilization is still a real issue in modern perfusion practice and to determine whether off pump coronary artery bypass techniques minimize this risk. Thirty patients undergoing routine elective coronary artery bypass graft (CABG) surgery were divided into two groups. Group 1 patients underwent off pump coronary artery bypass (OPCAB) procedures, and group 2 underwent CABG supported with CPB. Blood samples were taken from the CPB patients at the beginning, middle, and end of the procedure, from the suction line, from the arterial line, and from the venous line for measurement of fat emboli present. Samples were taken at corresponding time-points from the OPCAB patients for similar measurements. Fat emboli were counted manually using Oil red O staining and light microscopy. The fat emboli were sized using calibrated microspheres as a visual size contrast. No fat emboli were observed in any of the blood samples taken from the OPCAB patients. There were fat emboli present in all samples taken during CPB from all sources. The count was highest in the suction system and lowest in the venous blood and tended to increase during CPB. There was an absence of large fat emboli in the venous blood, which tends to indicate that the larger fat emboli lodge in the microvasculature. OPCAB surgery eliminates the risk of fat embolization in patients undergoing coronary revascularization. The suction system is the major source of fat emboli during CPB, and despite the multiple filtration components of the CPB system, fat emboli of various and significant sizes do reach the patient. Fat embolization remains a risk in routine elective CABG surgery. Cardiotomy suction sho

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Bhatt DL, Steg PG, Ohman EM, Hirsch AT, Ikeda Y, Mas JL, Goto S, Liau CS, Richard AJ, Röther J, Wilson PWF, Andersen-Dalheim H, Anderson P, Anell B, Arber S, Armstrong K, Arnot D, Baldam A, Barratt I, Barresi S, Beder J, Benson M, Bergman F, Best J, Bhasim R, Bovell G, Bowman N, Brkic M, Bromberger D, Brown D, Brown J, Brownstein M, Bruce A, Buonopane J, Burns S, Butler A, Byrne D, Carson J, Cassimatis P, Chaffey G, Chambers D, Chan WJ, Chan B, Cheatham J, Chen R, Cheong B, Cheung C, Chin J, Chiu A, Choo E, Chow A, Chow AM, Chung D, Conos M, Cooke N, Cooper S, Coulton P, Cranswick M, Crichton G, Dabscheck A, Dalitz J, Danishar J, Darzins A, Davidson D, Davis P, Dawood N, de Clifford M, de Looze F, de Sousa A, Devi S, Dickman J, Donald H, Dowell B, Dowey K, Eizenberg P, Eizenberg C, Elberg L, Enten P, Erhardt A, Fagan R, Fairweather D, Ferguson N, Ferguson P, Fernando C, Ferres M, Foley P, Fong S, Francis P, Gaddie D, Gallagher B, Gan R, Garland J, Gault A, Gianarakis N, Gibson D, Gill I, Giltrap M, Gingold R, Gordon N, Graham M, Grave M, Grigg J, Hall L, Hall M, Hancock K, Harrison C, Harrison R, Hayden R, Heale J, Healy P, Herold E, Hirst E, Hodby S, Hogan C, Horsfall P, Hutchinson A, Irmgard C, Jain S, Jefferson D, John R, John T, Kay B, Kelly P, Kester D, Khury J, Kirmos J, Kloot S, Kolos D, Korner J, Kratzing C, Kubicek J, Kumar A, Lacey C, Lahanis C, Lajoie D, Lam L, Lancaster M, Law H, Lawlor-Smith C, Laycock R, Lee I, Leung C, Levitt L, Lewi L, Liew J, Liew S, Lleweslyn D, Loth P, Lyon E, Maclaren S, Maher C, Maldari F, Manderson J, Mann L, Mannan MA, Marano F, Marinucci D, Matthews A, Matthews C, McGowan R, McGrath L, McKenna J, McNaughton E, McNiff M, Meaney J, Menzies J, Michaelson A, Michail S, Mitchell G, Molenaar R, Molloy P, Monaco-Mugliston E, Mooney C, Moor M, Moylan B, Nanayakkara V, Nathan P, Naughton W, Ng R, Nicholson K, Nixon M, Nuendorf G, O'Brien C, O'Hanlon P, Olesen J, Ong A, Ong SG, O'Toole M, Page M, Pahuja P, Palmer H, Parker S, Partridgeet al., 2006, International prevalence, recognition, and treatment of cardiovascular risk factors in outpatients with atherothrombosis, JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, Vol: 295, Pages: 180-189, ISSN: 0098-7484

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• Citations: 1275

Khan MT, Punjabi P, Bouchareb Y, Kindler H, Rimoldi OE, Camici PGet al., 2005, Absolute quantification of subepicardial and subendocardial blood flow in human hibernating myocardium, 27th Congress of the European-Society-of-Cardiology, Publisher: OXFORD UNIV PRESS, Pages: 438-438, ISSN: 0195-668X

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Weerasinghe A, Athanasiou T, Al-Ruzzeh S, Casula R, Tekkis PP, Amrani M, Punjabi P, Taylor K, Stanbridge R, Glenville Bet al., 2005, Functional renal outcome in on-pump and off-pump coronary revascularization: A propensity-based analysis, ANNALS OF THORACIC SURGERY, Vol: 79, Pages: 1577-1583, ISSN: 0003-4975

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• Citations: 39

Punjabi P P, 2005, Manual Of Cardiothoracic Surgery

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Kapur A, Malik IS, Bagger JP, Anderson JR, Kooner JS, Thomas M, Punjabi P, Mayet J, Millane T, Goedicke J, Jamrozik K, de Belder MA, Hall RJ, Beatt KJet al., 2005, The coronary artery revascularisation in diabetes (CARDia) trial: Background, aims, and design, AMERICAN HEART JOURNAL, Vol: 149, Pages: 13-19, ISSN: 0002-8703

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• Citations: 56

Nadra I, Dawson D, Schmitz SA, Punjabi PP, Nihoyannopoulos Pet al., 2004, Lipomatous hypertrophy of the interatrial septum: a commonly misdiagnosed mass often leading to unnecessary cardiac surgery, HEART, Vol: 90, ISSN: 1355-6037

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• Citations: 43

Day JRS, Punjabi PP, Randi AM, Haskard DO, Landis RC, Taylor KMet al., 2004, Clinical inhibition of the seven-transmembrane thrombin receptor (PAR1) by intravenous aprotinin during cardiothoracic surgery, CIRCULATION, Vol: 110, Pages: 2597-2600, ISSN: 0009-7322

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• Citations: 52

Hagl S, Whitaker, Grimm M, Bonser R, Westaby S, Boonstra P, Punjabi P, Svennevig Jet al., 2004, SOHO firewalls for enterprise access - Conference discussion, EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, Vol: 25, Pages: 273-274, ISSN: 1010-7940

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Asimakopoulos G, Al-Ruzzeh S, Ambler G, Omar RZ, Punjabi P, Amrani M, Taylor KMet al., 2003, An evaluation of existing risk stratification models as a tool for comparison of surgical performances for coronary artery bypass grafting between institutions, EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, Vol: 23, Pages: 935-942, ISSN: 1010-7940

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• Citations: 40

Samankatiwat P, Samartzis I, Lertsithichai P, Stefanou D, Punjabi PP, Taylor KM, Gourlay Tet al., 2003, Leucocyte depletion in cardiopulmonary bypass: a comparison of four strategies, PERFUSION-UK, Vol: 18, Pages: 95-105, ISSN: 0267-6591

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• Citations: 14

Nair KS, Lawrence DR, Punjabi PP, Taylor KMet al., 2002, Indications for cardiopulmonary bypass in non-cardiac operations, PERFUSION-UK, Vol: 17, Pages: 161-166, ISSN: 0267-6591

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• Citations: 5

Poullis M, Punjabi P, 2001, Concomitant thymectomy and cardiac operation in a patient with pure red cell aplasia, ANNALS OF THORACIC SURGERY, Vol: 72, Pages: 621-623, ISSN: 0003-4975

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• Citations: 6

Punjabi PP, Wyse RK, Taylor KM, 2000, Role of aprotinin in the management of patients during and after cardiac surgery., Expert Opin Pharmacother, Vol: 1, Pages: 1353-1365, ISSN: 1465-6566

Management of patients undergoing cardiac surgery has evolved in recent years as more is understood about the physiological changes and responses that occur during and after cardiopulmonary bypass (CPB). In particular, our understanding of the mechanisms involved in haemostasis and in the inflammatory response to bypass surgery, has allowed significant refinements in patient management. Improvements in the pharmacological conservation of blood loss have been striking, particularly with the development of the serine protease inhibitor, aprotinin (Trasylol, Bayer). Aprotinin represents a significant improvement, especially for patients at high risk, since it reduces the need for allogeneic and (sometimes scarce) blood products. However, in view of its cost, making an appropriate selection of patients most at risk of serious blood loss is a major consideration in the use of aprotinin. While its mechanisms of action are not well understood, the use of aprotinin also appears to reduce inflammatory response to CPB.

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Viagappan GM, Punjabi P, 1999, Group C streptococcal endocarditis, JOURNAL OF INFECTION, Vol: 38, Pages: 57-58, ISSN: 0163-4453

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Punjabi P, Murday A, 1997, Successful surgical repair of a false aneurysm of the ascending aorta following orthotopic cardiac transplantation: A case report, EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, Vol: 11, Pages: 1174-1175, ISSN: 1010-7940

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• Citations: 7

Narang R, Pathania OP, Punjabi P, Tomar Set al., 1987, Unusual Maydl's hernia (a case report)., J Postgrad Med, Vol: 33, Pages: 137-139, ISSN: 0022-3859

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Punjabi PP, Novel Annuloplasty ring for Mitral Valve Repair, PCT/US/2007/011948

A Sizeless, sutureless Annuloplasty ring for implantation in Mitral and Tricuspid valve repair

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PunjabiPP, Complex Mitral Valve Repair, European Association of Cardiothoracic Surgery

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