Imperial College London

ProfessorPatrickSerruys

Faculty of MedicineNational Heart & Lung Institute

Visiting Professor
 
 
 
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Contact

 

p.serruys

 
 
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Location

 

c/o Prof Kim FoxGuy Scadding BuildingRoyal Brompton Campus

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Summary

 

Publications

Publication Type
Year
to

926 results found

Grundeken MJ, Ishibashi Y, Ramcharitar S, Tuinenburg JC, Reiber JHC, Tu S, Aben J-P, Girasis C, Wykrzykowska JJ, Onuma Y, Serruys PWet al., 2015, The need for dedicated bifurcation quantitative coronary angiography (QCA) software algorithms to evaluate bifurcation lesions., EuroIntervention, Vol: 11 Suppl V, Pages: V44-V49

Single-vessel quantitative coronary angiography (QCA) software is inaccurate when used in bifurcation lesions due to the specific anatomical characteristics of bifurcations, including the natural step-down in diameters after every bifurcation. Dedicated bifurcation QCA software has been developed to overcome the limitations of single-vessel QCA in bifurcations. A phantom validation study has shown the superior accuracy of these bifurcation QCA algorithms compared to the single-vessel QCA software. These QCA software algorithms are currently highly recommended to assess bifurcation lesions.

Journal article

Kraak RP, Grundeken MJ, Onuma Y, Tu S, Wykrzykowska JJ, Chevalier B, Ormiston J, Serruys PWet al., 2015, The future of BRS in bifurcations., EuroIntervention, Vol: 11 Suppl V, Pages: V188-V192

Bioresorbable scaffolds (BRS) provide a new tool for percutaneous treatment of coronary stenosis. Initially, relatively simple coronary artery lesions were treated with this novel technology; nowadays, we have gained more experience with a wide variety of lesions, including bifurcation lesions. Data are limited in terms of the use of BRS in coronary bifurcation lesions, although it has been demonstrated that over time the bioresorbable struts are replaced by a tissue bridge resembling a "neo-carina". Furthermore, data are emerging about the endothelial shear stress (ESS) alterations and blood flow patterns after scaffold implantation. It is likely that ESS and blood flow determinations will guide correct future bifurcation techniques. In the future, BRS with thinner struts and more resistant to fracture are likely to improve bifurcation treatment with BRS.

Journal article

Battes LC, Akkerhuis KM, Cheng JM, Garcia-Garcia HM, Oemrawsingh RM, de Boer SPM, Regar E, van Geuns R-J, Serruys PW, Boersma E, Kardys Iet al., 2014, Circulating acute phase proteins in relation to extent and composition of coronary atherosclerosis and cardiovascular outcome: Results from the ATHEROREMO-IVUS study, INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol: 177, Pages: 847-853, ISSN: 0167-5273

Journal article

Oemrawsingh RM, Cheng JM, Garcia-Garcia HM, van Geuns R-J, de Boer SPM, Simsek C, Kardys I, Lenzen MJ, van Domburg RT, Regar E, Serruys PW, Akkerhuis KM, Boersma Eet al., 2014, Near-Infrared Spectroscopy Predicts Cardiovascular Outcome in Patients With Coronary Artery Disease, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 64, Pages: 2510-2518, ISSN: 0735-1097

Journal article

Karanasos A, Simsek C, Gnanadesigan M, van Ditzhuijzen NS, Freire R, Dijkstra J, Tu S, Van Mieghem N, van Soest G, de Jaegere P, Serruys PW, Zijlstra F, van Geuns R-J, Regar Eet al., 2014, OCT Assessment of the Long-Term Vascular Healing Response 5 Years After Everolimus-Eluting Bioresorbable Vascular Scaffold, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 64, Pages: 2343-2356, ISSN: 0735-1097

Journal article

de Boer SPM, Cheng JM, Garcia-Garcia HM, Oemrawsingh RM, van Geuns R-J, Regar E, Zijlstra F, Laaksonen R, Halperin E, Kleber ME, Koenig W, Boersma E, Serruys PWet al., 2014, Relation of genetic profile and novel circulating biomarkers with coronary plaque phenotype as determined by intravascular ultrasound: rationale and design of the ATHEROREMO-IVUS study, EUROINTERVENTION, Vol: 10, Pages: 953-960, ISSN: 1774-024X

Journal article

Ferenc M, Kornowski R, Belardi J, Serruys P, Silber S, Widimsky P, Windecker S, Neumann F-Jet al., 2014, Three-Year Outcomes of Percutaneous Coronary Intervention With Next-Generation Zotarolimus-Eluting Stents for De Novo Coronary Bifurcation Lesions, JOURNAL OF INVASIVE CARDIOLOGY, Vol: 26, Pages: 630-+, ISSN: 1042-3931

Journal article

Okamura T, Onuma Y, Yamada J, Iqbal J, Tateishi H, Nao T, Oda T, Maeda T, Nakamura T, Miura T, Yano M, Serruys PWet al., 2014, 3D optical coherence tomography: new insights into the process of optimal rewiring of side branches during bifurcational stenting, EUROINTERVENTION, Vol: 10, Pages: 907-915, ISSN: 1774-024X

Journal article

Zhang Y-J, Iqbal J, Nakatani S, Bourantas CV, Campos CM, Ishibashi Y, Cho Y-K, Veldhof S, Wang J, Onuma Y, Garcia-Garcia HM, Dudek D, van Geuns R-J, Serruys PWet al., 2014, Scaffold and Edge Vascular Response Following Implantation of Everolimus-Eluting Bioresorbable Vascular Scaffold A 3-Year Serial Optical Coherence Tomography Study, JACC-CARDIOVASCULAR INTERVENTIONS, Vol: 7, Pages: 1361-1369, ISSN: 1936-8798

Journal article

Cassese S, De Luca G, Ribichini F, Cernigliaro C, Sansa M, Versaci F, Proietti I, Stankovic G, Stojkovic S, Fernandez-Pereira C, Tomai F, Vassanelli C, Antoniucci D, Serruys PW, Kastrati A, Rodriguez AEet al., 2014, ORA1 iMmunosuppressive therapy to prevent in-Stent rEstenosiS (RAMSES) cooperation: A patient-level meta-analysis of randomized trials, ATHEROSCLEROSIS, Vol: 237, Pages: 410-417, ISSN: 0021-9150

Journal article

Onuma Y, Serruys PW, Muramatsu T, Nakatani S, van Geuns R-J, de Bruyne B, Dudek D, Christiansen E, Smits PC, Chevalier B, McClean D, Koolen J, Windecker S, Whitbourn R, Meredith I, Garcia-Garcia HM, Veldhof S, Rapoza R, Ormiston JAet al., 2014, Incidence and Imaging Outcomes of Acute Scaffold Disruption and Late Structural Discontinuity After Implantation of the Absorb Everolimus-Eluting Fully Bioresorbable Vascular Scaffold Optical Coherence Tomography Assessment in the ABSORB Cohort B Trial (A Clinical Evaluation of the Bioabsorbable Everolimus Eluting Coronary Stent System in the Treatment of Patients With De Novo Native Coronary Artery Lesions), JACC-CARDIOVASCULAR INTERVENTIONS, Vol: 7, Pages: 1400-1411, ISSN: 1936-8798

Journal article

Cheng JM, Oemrawsingh RM, Garcia-Garcia HM, Akkerhuis KM, Kardys I, de Boer SPM, Langstraat JS, Regar E, van Geuns R-J, Serruys PW, Boersma Eet al., 2014, Relation of C-Reactive Protein to Coronary Plaque Characteristics on Grayscale, Radiofrequency Intravascular Ultrasound, and Cardiovascular Outcome in Patients With Acute Coronary Syndrome or Stable Angina Pectoris (from the ATHEROREMO-IVUS Study), AMERICAN JOURNAL OF CARDIOLOGY, Vol: 114, Pages: 1497-1503, ISSN: 0002-9149

Journal article

Valgimigli M, Sabate M, Kaiser C, Brugaletta S, de la Torre Hernandez JM, Galatius S, Cequier A, Eberli F, de Belder A, Serruys PW, Ferrante Get al., 2014, Effects of cobalt-chromium everolimus eluting stents or bare metal stent on fatal and non-fatal cardiovascular events: patient level meta-analysis, BMJ-BRITISH MEDICAL JOURNAL, Vol: 349, ISSN: 1756-1833

Journal article

Garcia-Garcia HM, Serruys PW, Campos CM, Muramatsu T, Nakatani S, Zhang Y-J, Onuma Y, Stone GWet al., 2014, Assessing Bioresorbable Coronary Devices Methods and Parameters, JACC-CARDIOVASCULAR IMAGING, Vol: 7, Pages: 1130-1148, ISSN: 1936-878X

Journal article

Serruys PW, 2014, The acute ischaemic stroke team: one great step forward, EUROINTERVENTION, Vol: 10, Pages: 773-773, ISSN: 1774-024X

Journal article

Cheng JM, Oemrawsingh RM, Akkerhuis KM, Garcia-Garcia HM, de Boer SPM, Battes LC, Buljubasic N, Lenzen MJ, de Jaegere PPT, van Geuns R-J, Serruys PW, Kardys I, Boersma Eet al., 2014, Circulating chemokines in relation to coronary plaque characteristics on radiofrequency intravascular ultrasound and cardiovascular outcome, BIOMARKERS, Vol: 19, Pages: 611-619, ISSN: 1354-750X

Journal article

Echavarria-Pinto M, van de Hoef TP, Serruys PW, Piek JJ, Escaned Jet al., 2014, Facing the complexity of ischaemic heart disease with intracoronary pressure and flow measurements: beyond fractional flow reserve interrogation of the coronary circulation, CURRENT OPINION IN CARDIOLOGY, Vol: 29, Pages: 564-570, ISSN: 0268-4705

Journal article

de Boer SPM, Cheng JM, Range H, Garcia-Garcia HM, Heo JH, Akkerhuis KM, Meilhac O, Cosler G, Pussinen PJ, van Geuns R-J, Serruys PW, Boersma E, Kardys Iet al., 2014, Antibodies to periodontal pathogens are associated with coronary plaque remodeling but not with vulnerability or burden, ATHEROSCLEROSIS, Vol: 237, Pages: 84-91, ISSN: 0021-9150

Journal article

Mariani J, Guedes C, Soares P, Zalc S, Campos CM, Lopes AC, Spadaro AG, Perin MA, Esteves Filho A, Takimura CK, Ribeiro E, Kalil-Filho R, Edelman ER, Serruys PW, Lemos PAet al., 2014, Intravascular Ultrasound Guidance to Minimize the Use of Iodine Contrast in Percutaneous Coronary Intervention The MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) Randomized Controlled Trial, JACC-CARDIOVASCULAR INTERVENTIONS, Vol: 7, Pages: 1287-1293, ISSN: 1936-8798

Journal article

Head SJ, Davierwala PM, Serruys PW, Redwood SR, Colombo A, Mack MJ, Morice M-C, Holmes DR, Feldman TE, Stahle E, Underwood P, Dawkins KD, Kappetein AP, Mohr FWet al., 2014, Coronary artery bypass grafting vs. percutaneous coronary intervention for patients with three-vessel disease: final five-year follow-up of the SYNTAX trial, EUROPEAN HEART JOURNAL, Vol: 35, Pages: 2821-+, ISSN: 0195-668X

Journal article

Bax JJ, Delgado V, Bapat V, Baumgartner H, Collet JP, Erbel R, Hamm C, Kappetein AP, Leipsic J, Leon MB, MacCarthy P, Piazza N, Pibarot P, Roberts WC, Rodes-Cabau J, Serruys P, Thomas M, Vahanian A, Webb J, Zamorano JL, Windecker Set al., 2014, Open issues in transcatheter aortic valve implantation. Part 2: procedural issues and outcomes after transcatheter aortic valve implantation, EUROPEAN HEART JOURNAL, Vol: 35, Pages: 2639-+, ISSN: 0195-668X

Journal article

Bax JJ, Delgado V, Bapat V, Baumgartner H, Collet JP, Erbel R, Hamm C, Kappetein AP, Leipsic J, Leon MB, MacCarthy P, Piazza N, Pibarot P, Roberts WC, Rodes-Cabau J, Serruys PW, Thomas M, Vahanian A, Webb J, Luis Zamorano J, Windecker Set al., 2014, Open issues in transcatheter aortic valve implantation. Part 1: patient selection and treatment strategy for transcatheter aortic valve implantation, EUROPEAN HEART JOURNAL, Vol: 35, Pages: 2627-+, ISSN: 0195-668X

Journal article

Garcia-Garcia HM, Campos CM, Serruys PW, 2014, Women Are From SATURN and Men Are From an ASTEROID Deciphering the REVERSAL of Coronary Atheroma, JACC-CARDIOVASCULAR IMAGING, Vol: 7, Pages: 1023-1024, ISSN: 1936-878X

Journal article

Iqbal J, Serruys PW, 2014, Revascularization strategies for patients with stable coronary artery disease, JOURNAL OF INTERNAL MEDICINE, Vol: 276, Pages: 336-351, ISSN: 0954-6820

Journal article

Wang A, Nakatani S, Eggermont J, Onuma Y, Garcia-Garcia HM, Serruys PW, Reiber JHC, Dijkstra Jet al., 2014, Automatic detection of bioresorbable vascular scaffold struts in intravascular optical coherence tomography pullback runs, BIOMEDICAL OPTICS EXPRESS, Vol: 5, Pages: 3589-3602, ISSN: 2156-7085

Journal article

Serruys PW, 2014, The annual ESC Congress: a fixed point in a changing age., EuroIntervention, Vol: 10

Journal article

Zhang Y-J, Bourantas CV, Muramatsu T, Iqbal J, Farooq V, Diletti R, Campos CAM, Onuma Y, Garcia-Garcia HM, Serruys PWet al., 2014, Comparison of acute gain and late lumen loss after PCI with bioresorbable vascular scaffolds versus everolimus-eluting stents: an exploratory observational study prior to a randomised trial., EuroIntervention, Vol: 10, Pages: 672-680

AIMS: The study sought to compare the acute gain and two-year follow-up late lumen loss (LLL) between the Absorb bioresorbable vascular scaffold (BVS) and the analogous everolimus-eluting metallic stent (EES). The current analysis included all the patients recruited in the ABSORB Cohort B and SPIRIT II trials implanted with a single 3.0×18 mm device (Absorb BVS or EES) who underwent serial angiographic examinations at baseline and at two-year follow-up. The acute gain was defined as the difference between post- and preprocedural minimal lumen diameter (MLD). The in-stent/scaffold LLL was calculated as the difference in stent/scaffold segment between the post-procedural MLD and follow-up MLD. Thirty-three patients (33 lesions) implanted with the Absorb BVS, and 26 patients (28 lesions) implanted with the EES were studied. The acute gain was similar in the Absorb BVS group (1.23±0.38 mm) compared to the EES group (1.32±0.26 mm, p=0.29). The in-stent/scaffold LLL at two-year follow-up in the Absorb BVS group (0.26±0.19 mm) was also similar compared to the EES group (0.22±0.22 mm, p=0.29). Although the two groups had similar two-year clinical outcomes (major adverse cardiac events: Absorb BVS: 6.1% vs. EES: 0.0%), patients treated with the Absorb BVS exhibited a significantly lower two-year in-stent/scaffold MLD compared to the EES (2.02±0.26 mm vs. 2.22±0.34 mm, p=0.01). Although BVS and EES demonstrated similar two-year clinical outcomes, patients treated with the Absorb BVS exhibited a significantly lower two-year in-stent/scaffold MLD compared to patients treated with the EES. Appropriately powered randomised trials are necessary to confirm these exploratory results and evaluate their prognostic and clinical significance.

Journal article

Cohen DJ, Osnabrugge RL, Magnuson EA, Wang K, Li H, Chinnakondepalli K, Pinto D, Abdallah MS, Vilain KA, Morice M-C, Dawkins KD, Kappetein AP, Mohr FW, Serruys PWet al., 2014, Cost-Effectiveness of Percutaneous Coronary Intervention With Drug-Eluting Stents Versus Bypass Surgery for Patients With 3-Vessel or Left Main Coronary Artery Disease Final Results From the Synergy Between Percutaneous Coronary Intervention With TAXUS and Cardiac Surgery (SYNTAX) Trial, CIRCULATION, Vol: 130, Pages: 1146-1157, ISSN: 0009-7322

Journal article

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