Imperial College London


Faculty of MedicineNational Heart & Lung Institute

Visiting Professor







c/o Prof Kim FoxGuy Scadding BuildingRoyal Brompton Campus






BibTex format

author = {García-García, HM and Gonzalo, N and Granada, JF and Regar, E and Serruys, PW},
doi = {10.1586/14779072.6.2.209},
journal = {Expert Rev Cardiovasc Ther},
pages = {209--222},
title = {Diagnosis and treatment of coronary vulnerable plaques.},
url = {},
volume = {6},
year = {2008}

RIS format (EndNote, RefMan)

AB - Thin-capped fibroatheroma is the morphology that most resembles plaque rupture. Detection of these vulnerable plaques in vivo is essential to being able to study their natural history and evaluate potential treatment modalities and, therefore, may ultimately have an important impact on the prevention of acute myocardial infarction and death. Currently, conventional grayscale intravascular ultrasound, virtual histology and palpography data are being collected with the same catheter during the same pullback. A combination of this catheter with either thermography capability or additional imaging, such as optical coherence tomography or spectroscopy, would be an exciting development. Intravascular magnetic resonance imaging also holds much promise. To date, none of the techniques described above have been sufficiently validated and, most importantly, their predictive value for adverse cardiac events remains elusive. Very rigorous and well-designed studies are compelling for defining the role of each diagnostic modality. Until we are able to detect in vivo vulnerable plaques accurately, no specific treatment is warranted.
AU - García-García,HM
AU - Gonzalo,N
AU - Granada,JF
AU - Regar,E
AU - Serruys,PW
DO - 10.1586/14779072.6.2.209
EP - 222
PY - 2008///
SP - 209
TI - Diagnosis and treatment of coronary vulnerable plaques.
T2 - Expert Rev Cardiovasc Ther
UR -
UR -
VL - 6
ER -