Imperial College London


Faculty of MedicineNational Heart & Lung Institute

Visiting Professor







c/o Prof Kim FoxGuy Scadding BuildingRoyal Brompton Campus






BibTex format

author = {Campos, CM and Christiansen, EH and Stone, GW and Serruys, PW},
doi = {10.4244/EIJV11SVA26},
journal = {EuroIntervention},
pages = {V115--V119},
title = {The EXCEL and NOBLE trials: similarities, contrasts and future perspectives for left main revascularisation.},
url = {},
volume = {11 Suppl V},
year = {2015}

RIS format (EndNote, RefMan)

AB - Unprotected left main coronary artery (ULMCA) stenosis has relatively high prevalence and exposes patients to a high risk for adverse cardiovascular events. The optimal revascularisation strategy (coronary artery bypass surgery [CABG] or percutaneous coronary intervention [PCI]) for patients with complex coronary artery disease is a topic of continuing debate. The introduction of the newer-generation drug-eluting stents (DES) -with documented improvements in both safety and efficacy- has prompted the interventional community to design two new dedicated randomised trials comparing CABG and PCI: the NOBLE (Coronary Artery Bypass Grafting Vs Drug Eluting Stent Percutaneous Coronary Angioplasty in the Treatment of Unprotected Left Main Stenosis) and EXCEL (Evaluation of XIENCE Everolimus Eluting Stent Versus Coronary Artery Bypass Surgery for Effectiveness of Left Main Revascularization) trials. The aims of the present review are to describe the similarities and contrasts between these two trials as well to explore their future implications in ULMCA treatment.
AU - Campos,CM
AU - Christiansen,EH
AU - Stone,GW
AU - Serruys,PW
DO - 10.4244/EIJV11SVA26
EP - 119
PY - 2015///
SP - 115
TI - The EXCEL and NOBLE trials: similarities, contrasts and future perspectives for left main revascularisation.
T2 - EuroIntervention
UR -
UR -
VL - 11 Suppl V
ER -