Imperial College London
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DrPaulStrutton

Faculty of Medicine, Department of Surgery & Cancer

Reader in Human Neurophysiology
 
 
 
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Contact

 

+44 (0)20 7594 3239p.strutton

 
 
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Location

 

205Sir Michael Uren HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Mullington:2018:10.1111/anae.14454,
author = {Mullington, CJ and Low, DA and Strutton, PH and Malhotra, S},
doi = {10.1111/anae.14454},
journal = {Anaesthesia},
pages = {1500--1506},
title = {Body temperature, cutaneous heat loss and skin blood flow during epidural anaesthesia for emergency caesarean section},
url = {http://dx.doi.org/10.1111/anae.14454},
volume = {73},
year = {2018}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - It is not clear how converting epidural analgesia for labour to epidural anaesthesia for emergency caesarean section affects either cutaneous vasomotor tone or mean body temperature. We hypothesised that topping up a labour epidural blocks active cutaneous vasodilation (cutaneous heat loss and skin blood flow decrease), and that as a result mean body temperature increases. Twenty women in established labour had body temperature, cutaneous heat loss and skin blood flow recorded before and after epidural topup for emergency caesarean section. Changes over time were analysed with repeated measures ANOVA. Mean (SD) mean body temperature was 36.8 (0.5)°C at epidural topup and 36.9 (0.6)°C at delivery. Between epidural topup and delivery, the mean (SD) rate of increase in mean body temperature was 0.5 (0.5) °C.h−1. Following epidural topup, chest (p < 0.001) and forearm (p = 0.004) heat loss decreased, but head (p = 0.05), thigh (p = 0.79) and calf (p = 1.00) heat loss did not change. The mean (SD) decrease in heat loss was 15 (19) % (p < 0.001). Neither arm (p = 0.06) nor thigh (p = 0.10) skin blood flow changed following epidural topup. Despite the lack of change in skin blood flow, the most plausible explanation for the reduction in heat loss and the increase in mean body temperature is blockade of active cutaneous vasodilation. It is possible that a similar mechanism is responsible for the hyperthermia associated with labour epidural analgesia.
AU  - Mullington,CJ
AU  - Low,DA
AU  - Strutton,PH
AU  - Malhotra,S
DO  - 10.1111/anae.14454
EP  - 1506
PY  - 2018///
SN  - 0003-2409
SP  - 1500
TI  - Body temperature, cutaneous heat loss and skin blood flow during epidural anaesthesia for emergency caesarean section
T2  - Anaesthesia
UR  - http://dx.doi.org/10.1111/anae.14454
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000449669200008&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://onlinelibrary.wiley.com/doi/full/10.1111/anae.14454
UR  - http://hdl.handle.net/10044/1/79792
VL  - 73
ER  -
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