Imperial College London
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Dr Paul Turner

Faculty of Medicine, National Heart & Lung Institute

Reader in Paediatric Allergy & Clinical Immunology
 
 
 
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Contact

 

+44 (0)20 3312 7754p.turner

 
 
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Location

 

Children's Clinical Research FacilityCambridge WingSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Dodd:2021:10.1016/j.resuscitation.2021.04.010,
author = {Dodd, A and Hughes, A and Sargant, N and Whyte, AF and Soar, J and Turner, P},
doi = {10.1016/j.resuscitation.2021.04.010},
journal = {Resuscitation},
pages = {86--96},
title = {Evidence update for the treatment of anaphylaxis},
url = {http://dx.doi.org/10.1016/j.resuscitation.2021.04.010},
volume = {163},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The Resuscitation Council UK has updated its Guideline for healthcare providers on the Emergency treatment of anaphylaxis. As part of this process, an evidence review was undertaken by the Guideline Working Group, using an internationally-accepted approach for adoption, adaptation, and de novo guideline development based on the Grading of Recommendations Assessment, Development and Evaluation (GRADE) evidence to decision (EtD) framework, referred to as GRADE-ADOLOPMENT. A number of significant changes have been made, which will be reflected in the updated Guideline. These include: emphasis on repeating intramuscular adrenaline doses after 5min if symptoms of anaphylaxis do not resolve; corticosteroids (e.g. hydrocortisone) no longer being routinely recommended for the emergency treatment of anaphylaxis; interventions for reactions which are refractory to initial treatment with adrenaline; a recommendation against the use of antihistamines for the acute management of anaphylaxis; and guidance relating to the duration of observation following anaphylaxis, and timing of discharge.
AU  - Dodd,A
AU  - Hughes,A
AU  - Sargant,N
AU  - Whyte,AF
AU  - Soar,J
AU  - Turner,P
DO  - 10.1016/j.resuscitation.2021.04.010
EP  - 96
PY  - 2021///
SN  - 0300-9572
SP  - 86
TI  - Evidence update for the treatment of anaphylaxis
T2  - Resuscitation
UR  - http://dx.doi.org/10.1016/j.resuscitation.2021.04.010
UR  - http://hdl.handle.net/10044/1/89524
VL  - 163
ER  -
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